<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29179

Description Mediator complex subunit 24
SequenceMKVINLKQAILQAWKERWSDYQWAINIKKNFPKGATWDYPNLAEALMEQAMIGLSPNPLILYYLKYAVSSQMVSYSSVLTAISKFDDFSRDLCVKSLFEIMDMFCHHLSCHGKAEECVGLCRALLTVVTWLLQGCDWYCEKLREMGPSVSTETSLSACLDRLHTLMSSNKNRALVHIAWLEDQGAWNNVEQAVMKLTEGLDGVANQALRTKLEECLSLVKGIPTMLAVQCDQPVHALFPSVHAFIMLEGTMNLTGETQPLVEQLMMIKRMQKIPTALFVLKIWKACFTGLIESPEGTEELKWTAFTFLKVKYTLAHLEPSMDFMEDVNVAFQHLLKLTPLLDKADQRCNCDCLGMLLQECHKLGLLSEVNTSCLTAKRYKFREFAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHMVQTYGSEVILSDPSPSGETPFFETWLQTGMPEEGKTLNPDHPCFRPEPGKVESLVTLLNNSSEMKLVQVKWHEICHSIPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVSHVRMLGRDEREKPQTMIRQLVTPLYGEHTLQFYNERVIIMSSIMERMCADIFQQTGATLRPPMDGQESIPYRNLLPAKDPIHTSLSKQFQAVLSKGWVDSQALHLFDSLLNMGGVFWFTNNLIKELLKETRQEWANRVVELLYSIFCLDTQQITLTLLGTIVPNLLTDSAHWHSLTDPPGKALAKLCVWCALSSYSSHPKGSFSARQRKRHREDIEDYNSLFPLDDTQPSKLMRLLSSNEDEPAALSSPADRSMSSSLSASQLHTVNMREPLNRVLANLFLLISSIVGSKMAGPHTQFVQSFIEECVECLEQGSRGSILQFMPFTMVSELVKLPALAKPRVVLAITDLTLPLGRRVAAKAISAL
Length983
PositionTail
OrganismTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Tetraodontiformes> Tetradontoidea> Tetraodontidae> Tetraodon.
Aromaticity0.07
Grand average of hydropathy-0.012
Instability index43.92
Isoelectric point6.63
Molecular weight109991.85
Publications
PubMed=15496914

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
enteric nervous system development	GO:0048484	IEA:Ensembl
interstitial cell of Cajal differentiation	GO:0061453	IEA:Ensembl
retinal cone cell development	GO:0046549	IEA:Ensembl
thymus development	GO:0048538	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29179
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.96|      26|     115|     415|     440|       3
---------------------------------------------------------------------------
  415-  440 (45.57/26.88)	KTVDADHSK.SPE.GLLGVLGHMLSGKS
  531-  558 (38.40/21.57)	KTLNPDHPCfRPEpGKVESLVTLLNNSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.81|      31|     222|     113|     175|       4
---------------------------------------------------------------------------
  113-  149 (45.36/79.33)	KAEECVGLCRALLTVvtwLLQGCDwycEKLREMGPSV
  211-  241 (56.45/23.12)	KLEECLSLVKGIPTM...LAVQCD...QPVHALFPSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.03|      10|     481|     163|     202|       9
---------------------------------------------------------------------------
  171-  180 (18.75/27.37)	NRALVHIAWL
  608-  617 (19.28/17.55)	SMAICAVAWL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.82|      17|      23|     331|     348|      10
---------------------------------------------------------------------------
  331-  348 (25.37/25.75)	FQHLLKLTpLLDKADQRC
  357-  373 (30.45/23.64)	LQECHKLG.LLSEVNTSC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.68|      21|      21|     870|     890|      11
---------------------------------------------------------------------------
  870-  890 (33.60/21.19)	DRSMSS.SLSASQLHTVNMREP
  892-  913 (27.08/15.60)	NRVLANlFLLISSIVGSKMAGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29179 with Med24 domain of Kingdom Metazoa
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