<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29175

Description Mediator complex subunit 23
SequenceMEAQLQSIFEDVVKTEIIEEAFAGMFMDTPEDERTKLITCLGAFRQYWVTLPLESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETSLLPPRMVCAALISSDSLEWERTQLWALTFKLIRKIIGGVDYKGVRDLLKAVLDKIQTIPTTVSSSIVQQLLAAREVVEYILDRNACLLPAYFAVTEIRKLYPEGKLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPSTLHFPLKGMLPFDKELFEPQTGLLRYVLEQPYSREMVCNMLGLNKQQKQRCPVLEEQLVDLVVYAMERSESEEHFDADVGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLNKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDITKPQSTHSFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKTLGMSDYKIALLCNAYSTNSECFPLPMGALVETIYGNGTMRINLPGTNCMASAAVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSIALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKCHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHENNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMNYHKKYPEKLYFEGLAEQVSPPMQLQSQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGSLYKFHDRPVTYLYNTLHYYERQLRDRTNLKRKLVHAIMSSLKDNRSPGWCLSETYLKFGINPREDNVWIPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLVITALPEPYWIVLHDRIVSVISSPALTSETEWAGYPFALLDFTACHQSYSEMNCSYVLALAHAVWHHSSIGQLSLIPKFLSETLKPIVQTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSFMDPICDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRTAHIITH
Length1337
PositionTail
OrganismTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Tetraodontiformes> Tetradontoidea> Tetraodontidae> Tetraodon.
Aromaticity0.10
Grand average of hydropathy-0.009
Instability index44.49
Isoelectric point6.94
Molecular weight153244.40
Publications
PubMed=15496914

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29175
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.23|      38|     212|     171|     255|       1
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  174-  214 (62.15/124.13)	NACL..LPAY.FAVTEIRKLYPEGKLSHWLL...GSLISdFVDsfRP
  960- 1003 (55.08/14.88)	NVCLrfLPVFdIVIHRFLELLPVSKSLETLLdhlGSLYK.FHD..RP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     576.35|     219|     360|     641|     935|       2
---------------------------------------------------------------------------
  586-  858 (334.14/269.24)	FISQLL...PNVFKCHAWGIL..HTLLEMFSYRMHHIQPHYRVQLLSHLH...............................................................slaavpqtnqNQLHL....CVESTAL..RLITALGSS...EVQPQFTrfLSDPKTVLSAESEELNraliltlarathvtdFFTGSDSIhgtWCKDI...LQTIMNFTP.....HNW........ASHTLSCFPAPLQAFfkqnNVPQESRFNLKKNV.........EEEYRKWksMANENDIITHFsmqgSPPLflcllWKMLLEtdhinqigfRVLERIGARALVAHVR.TFADFLVYEFSTSAGGQQLNKC..IEILNDMVWK
  886-  935 ( 1.42/23.21)	FIIQLLllkPNDFRNRVNDFVkeNAPEHWLQSDWHNKHMNYHKKYPEKLY........................................................................................................................................................................................................................................................................................................................................
 1009- 1219 (240.79/131.92)	..................................................feglaeqvsppmqlqsqylpiyfgnvclrflpvfdivihrflellpvsksletlldhlgslykfhdrpvtylyNTLHYyerqLRDRTNLkrKLVHAIMSSlkdNRSPGWC..LSETYLKFGINPREDN...............VWIPDDTY...YCKLIgrlVDTMAGKSPgpfpnCDWrfnefpnpAAHALHVTCVELMAL....AVPGKDVGNALLNVvlksqplvpRENITAW..MNAIGLVITAL....PEPY.....WIVLHD.........RIVSVISSPALTSETEwAGYPFALLDFTACHQSYSEMNCsyVLALAHAVWH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.68|      28|      30|     470|     497|       3
---------------------------------------------------------------------------
  470-  497 (51.81/31.73)	GMSDYKIALLCNAYSTNSECFPLPMGAL
  503-  530 (50.86/31.01)	GNGTMRINLPGTNCMASAAVTPLPMNLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.63|      19|     292|     939|     957|       4
---------------------------------------------------------------------------
  939-  957 (34.97/22.13)	LAEQVSPPMQLQSQYLPIY
 1233- 1251 (32.66/20.17)	LSETLKPIVQTEFQLLYVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      35|     341|     350|       5
---------------------------------------------------------------------------
  341-  350 (18.69/12.42)	IFFVLFQFAS
  374-  383 (19.45/13.28)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.18|      13|      35|     411|     425|       6
---------------------------------------------------------------------------
  411-  425 (21.18/18.26)	IPVPDITKPQstHSF
  447-  459 (26.00/15.31)	IPIPHSLKLH..HEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.55|      20|      35|     262|     281|       7
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  262-  281 (35.36/25.03)	LFEPQTGLLRYVLEQPYSRE
  300-  319 (32.19/22.09)	LEEQLVDLVVYAMERSESEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.74|      10|      27|     135|     144|       9
---------------------------------------------------------------------------
  135-  144 (15.32/ 9.86)	RDLLKAVLDK
  164-  173 (16.41/11.12)	REVVEYILDR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29175 with Med23 domain of Kingdom Metazoa
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