<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29157

Description Mediator complex subunit 23
SequenceMALSMEAQLQSIFEDVVKTEIIEEAFAGMFMDTPEDERTKLITCLGAFRQYWVTLPLESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETSLLPPRMVCAALISSDSLEWERTQLWALTFKLIRKIIGGVDYKGVRDLLKAVLDKIQTIPTTVSSSIVQQLLAAREVVEYILDRNACLLPAYFAVTEIRKLYPEGKLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPSTLHFPLKGMLPFDKELFEPQTGLLRYVLEQPYSREMVCNMLGLNKQTLNIAQQKQRCPVLEEQLVDLVVYAMERSESEEHFDADVGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLNKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDITKPQSTHSFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKTLGMSDYKIALLCNAYSTNSECFPLPMGALVETIYGNGTMRINLPGTNCMASAAVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSIALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKCHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHENNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMNYHKKYPEKLYFEGLAEQVSPPMQLQSQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGSLYKFHDRPVTYLYNTLHYYERQLRDRTNLKRKLVHAIMSSLKDNRSPGWCLSETYLKFGINPREDNVWIPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLVITALPEPYWIVLHDRIVSVISSPALTSETEWAGYPFALLDFTACHQSYSEMNCSYVLALAHAVWHHSSIGQLSLIPKFLSETLKPIVQTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSFMDPICDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRTAHIITH
Length1347
PositionTail
OrganismTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Tetraodontiformes> Tetradontoidea> Tetraodontidae> Tetraodon.
Aromaticity0.10
Grand average of hydropathy-0.002
Instability index44.65
Isoelectric point6.94
Molecular weight154287.64
Publications
PubMed=15496914

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29157
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.68|      28|      30|     480|     507|       1
---------------------------------------------------------------------------
  480-  507 (51.81/32.34)	GMSDYKIALLCNAYSTNSECFPLPMGAL
  513-  540 (50.86/31.61)	GNGTMRINLPGTNCMASAAVTPLPMNLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     216.50|      58|     301|     949|    1024|       2
---------------------------------------------------------------------------
  178-  218 (37.20/12.50)	.........NACL..LPAY.FAVTEIRK........LYPEGK.....LSHwlLGSLISdFVDsfRP.........
  598-  654 (82.28/36.33)	SQLLPNVFKCHAWGIL.......HTLLEmfsyrmhhIQPHYRV..QLLSH..LHSLAA.V.....PQTN.QNQLH
  961- 1022 (97.03/84.90)	SQYLPIYFGNVCLRFLPVFdIVIHRFLE........LLPVSKSleTLLDH..LGSLYK.FHD..RPVTYlYNTLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      30|     351|     360|       3
---------------------------------------------------------------------------
  351-  360 (18.69/ 9.92)	IFFVLFQFAS
  384-  393 (19.45/10.61)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     630.19|     198|     364|     723|     945|       4
---------------------------------------------------------------------------
  723-  945 (322.56/307.07)	WCKDI...LQTI..............MNFTPhNWASHTLSCFPAPLQAFfkqnNVPQESRFNLKKNV.........EEEYRKWksMANENDIITHFsmqgSPPLflcllWKMLLEtdhinqigfRVLERIGARALVAHVR.TFADFLVYEFSTSAGGQQLNKC..IEILNDMVWKYNIVTLDRLI...LCLAMRSHENNEAQV..CYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMNYHKKYPEKLY
 1080- 1311 (307.63/230.50)	YCKLIgrlVDTMagkspgpfpncdwrFNEFP.NPAAHALHVTCVELMAL....AVPGKDVGNALLNVvlksqplvpRENITAW..MNAIGLVITAL....PEPY.....WIVLHD.........RIVSVISSPALTSETEwAGYPFALLDFTACHQSYSEMNCsyVLALAHAVWHHSSIGQLSLIpkfLSETLKPIVQTEFQLlyVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSFMDPICDFLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.18|      13|      33|     421|     435|       5
---------------------------------------------------------------------------
  421-  435 (21.18/16.34)	IPVPDITKPQstHSF
  457-  469 (26.00/13.69)	IPIPHSLKLH..HEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.54|      27|      30|     259|     287|       6
---------------------------------------------------------------------------
  259-  285 (48.93/42.01)	MLPFDKE.............LFEPQTGLLRYVLEQPYSRE
  290-  329 (35.61/20.90)	MLGLNKQtlniaqqkqrcpvLEEQLVDLVVYAMERSESEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29157 with Med23 domain of Kingdom Metazoa
Unable to open file!