<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29148

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKCIPVPDINKPQSTHAFAMTCIWIHLNRKAQNGDSTLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRVPLPGTSCLASASVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHTKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSHRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTDENEIITQFSVQGFPPLFLCLLWKMLLETDHISQIGYKVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQSDWHTKHMSYHKKYPEKLYFEGLAEQVDPPVPIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMCLRNRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKHAMNAREDNPWVPEDSYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVNVISSSSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEALLPVVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAVPPQALNSGSPAPQSNQVPASLPVTQ
Length1010
PositionTail
OrganismMus musculus (Mouse)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Myomorpha> Muroidea> Muridae> Murinae> Mus> Mus.
Aromaticity0.10
Grand average of hydropathy-0.037
Instability index49.12
Isoelectric point7.08
Molecular weight115403.43
Publications
PubMed=19468303
PubMed=21183079

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29148
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     215.66|      41|      91|     706|     746|       1
---------------------------------------------------------------------------
  542-  571 (41.56/21.21)	...........RVSDFVKENSPE.H..WLQSDW...HTKHMSYHKKY
  572-  606 (38.68/19.23)	PEKLYFEGLAEQVDPPVPIQSPYlPiyFGNVCL...RF.........
  706-  746 (76.90/45.54)	PEDSYYCKLIGRLVDTMAGKSPG.P..FPNCDW...RFNEFPNPAAH
  800-  840 (58.53/32.90)	PE.PYWIVLHDRIVNVISSSS...L..TSETEWvgyPFRLFDFTACH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.04|      19|      81|     417|     435|       2
---------------------------------------------------------------------------
  417-  435 (34.60/26.13)	NEIITQFSVQGFPPLFLCL
  494-  512 (34.44/25.97)	NDMVWKYNIVTLDRLILCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     206.49|      67|      81|      84|     153|       3
---------------------------------------------------------------------------
   84-  153 (110.95/73.96)	STLQIPIP..HSLKLHHEF.LQQSLRNKSLQMNDYK..IALLCNAYSTNSEcftLPMGALVETIYGNGIMRVPLP
  162-  233 (95.54/55.68)	SVTPLPMNllDSLTVHAKMsLIHSIATRVIKLAHTKssVALAPALVETYSR...LLVYMEIESLGIKGFISQLLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.48|      18|     262|     614|     631|       6
---------------------------------------------------------------------------
  614-  631 (31.41/17.42)	IHRFL..ELLPVSKSLETLL
  870-  889 (27.07/14.09)	IPKFLteALLPVVKTEFQLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     133.90|      38|     330|      12|      55|       9
---------------------------------------------------------------------------
   12-   55 (61.87/56.17)	FDDGGTS.QLLWqhlsSQLIFFVLFQFAsfPHMVLSLHQKCIPVP
  343-  381 (72.02/47.16)	FFTGSDSiQGTW....CKDILQTIMNFT..PHNWASHTLSCFPAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29148 with Med23 domain of Kingdom Metazoa
Unable to open file!