<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29132

Description Uncharacterized protein
SequenceMVVPPMEGAAQSGGNMVADVVFVIEGTANLGPYFESLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAFEFVTWLDSIQFMGGGGETCSLIAEGLSTALQLFDDFKKLREQITGNVQKTSSSPAASQPTRIQKVEAWVLQGGKTREGQTGQKDARVSTPSKNRKYPHFADTPGHTENKLGEGNILQSCRGVFLVCGFLGGGATSATQSKQVVPQAPPTVQSQTSLLSTPSQPSQLPPGSAQQVAPPGSLSAAQAAAKMAVEAANSQKPGLATRFFSSAVPNLSQHPNTSGVGPPFSQPPVPTMTPGPISKMPPSTASLIPMTSQASLLPQQQQSQQPSQPSQQPLQPGGVPPGPVNVPQPGASQMGGVQLPGPQQGMANKVMAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNPGENLKTDQWPQKLIMQLIPQQLLSTLGSLFRNSRMVQFQFTNKDLESLKGLYRIMGNGFAGCVHFPHSTPCEVRVLMLLYSSKKKIFMGLIPNDQSGFVNGIRQVITNHKQVQQQKIEQQRTQLGATQPMTTGAVSAPQGFLQKQPGTLPVSQGMQLQMPSQPVTSGMSQVNPVPMMDEQQRQQNLVSLTLFFFSPLNPLVFPGKRVGMGLGGGGGAMALV
Length663
PositionUnknown
OrganismLatimeria chalumnae (Coelacanth)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Coelacanthiformes> Coelacanthidae> Latimeria.
Aromaticity0.06
Grand average of hydropathy-0.291
Instability index53.53
Isoelectric point9.11
Molecular weight70645.81
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29132
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     312.26|      55|      56|     282|     336|       1
---------------------------------------------------------------------------
  234-  272 (47.64/11.62)	..........KQV.VPQApptvQSQTSLLST........P....SQ.P..SQ...LPP...................GSAQQVAP....PG
  273-  331 (91.09/27.52)	SLSAA.qaaaKMA.VEAA....NSQKPGLATRFFS.SAVP..NLSQHPNTSG...VGP...................PFSQPPVP.TMTPG
  332-  378 (54.56/14.15)	PISKM..ppsTAS.LIPM....TSQA..........SLLPqqQQSQQP........SQ...................PSQQPLQPgGVPPG
  379-  443 (65.38/18.11)	PVNVPqpgasQMGgVQLP....GPQQ.GMANKVMAwSGVL..EWQEKPKPAS...VDA...............ntklTRSLPCQV.YVNPG
  576-  646 (53.60/13.80)	AVSAPqgflqKQP.GTLP....VSQGMQL.............QMPSQPVTSGmsqVNPvpmmdeqqrqqnlvsltlfFFS.PLNP.LVFPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.69|      41|      54|      43|      93|       2
---------------------------------------------------------------------------
    5-   52 (64.75/39.15)	PMEG..AAQSGGNMVADVVFvieGTANLGP..YFE.....SLR..khylLPAIEYFNGG
   54-  109 (54.94/51.19)	PAETdfGGDYGGTQYSLVVF...NTVDCAPesYVQchaptSSAfefvtwLDSIQFMGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.57|      16|      23|     457|     473|       3
---------------------------------------------------------------------------
  457-  473 (23.41/14.52)	MQLIPQQLLStLGSLFR
  480-  495 (28.16/13.59)	FQFTNKDLES.LKGLYR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29132 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATQSKQVVPQAPPTVQSQTSLLSTPSQPSQLPPGSAQQVAPPGSLSAAQAAAKMAVEAANSQKPGLATRFFSSAVPNLSQHPNTSGVGPPFSQPPVPTMTPGPISKMPPSTASLIPMTSQASLLPQQQQSQQPSQPSQQPLQPGGVPPGPVNVPQPGASQMGGVQLPGPQQG
2) EAWVLQGGKTREGQTGQKDARVSTPSKNRKYPHFADTPGHTENKLGE
230
160
401
206










Molecular Recognition Features






MoRF SequenceStartStop




NANANA