<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29116

Description Transcription elongation factor A3
SequenceMAREKELIRIAKQLDNMVARKNREGILGLLRELKGYSMTLKLLQTTRIGMAVNAVRKHCTDEEIAALAKILIKNWKRLLVAERSEYRRNSLDSKLSSSPPERKHPLDSKKEKGCSGTTLPSTQAHALTQRDSFDSKFGSSPPCQKKHLSNSKKERKDSTDSKSNSHSATPKKHSLEIKAVQKFRTSSPPPKRPSTEATVERSDAMKMKSEAPRTPTSPGSPVFSPSSPPFLPPTFLTGDSIRDKCIEMLAAALRTDGEKNWNCNPYRAWVFAENMYSSCSGRSVPSFSDPGSHRTVLPAFALRIYQEMKSTDMKYKNRVRSRISNLKDPKNPSLRKSVLSGAISLSDIAKMTAEEMASDELKELRNILTQEAIREHQMSKTGGTATDLFQCGKCKKKNCTYTQVQTRSADEPMTMFVLCNECGNRWKFC
Length429
PositionUnknown
OrganismLatimeria chalumnae (Coelacanth)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Coelacanthiformes> Coelacanthidae> Latimeria.
Aromaticity0.05
Grand average of hydropathy-0.748
Instability index54.31
Isoelectric point9.76
Molecular weight48131.73
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29116
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     209.35|      39|      40|      87|     125|       1
---------------------------------------------------------------------------
   87-  125 (66.17/34.64)	RRNSLDSKLSSSP...................................P.ERKHPLDSKKEKGCSGTTLPSTQAH
  129-  166 (55.39/27.82)	QRDSFDSKFGSSP...................................PcQKKHLSNSKKERKDS..TDSKSNSH
  176-  213 (53.26/26.47)	EIKAVQKFRTSSP...................................P.PKRPSTEATVERS.DAMKMKSEAPR
  217-  286 (34.53/14.62)	SPGSPVFSPSSPPflpptfltgdsirdkciemlaaalrtdgeknwncnP.YRAWVFAENMYSSCSGRSVPS....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.19|      25|      40|     289|     313|       2
---------------------------------------------------------------------------
  289-  313 (44.84/32.29)	DPGS...HRTVLP.AFALRIYQEMKSTDM
  328-  356 (31.35/20.48)	DPKNpslRKSVLSgAISLSDIAKMTAEEM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.10|      23|     184|      53|      75|       3
---------------------------------------------------------------------------
   53-   75 (40.05/28.88)	NAVRKHCTDEEIAALAKILIKNW
  239-  261 (41.05/29.76)	DSIRDKCIEMLAAALRTDGEKNW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29116 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NSLDSKLSSSPPERKHPLDSKKEKGCSGTTLPSTQAHALTQRDSFDSKFGSSPPCQKKHLSNSKKERKDSTDSKSNSHSATPKKHSLEIKAVQKFRTSSPPPKRPSTEATVERSDAMKMKSEAPRTPTSPGSPVFSPSSPP
89
229










Molecular Recognition Features






MoRF SequenceStartStop




NANANA