<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29110

Description Cyclin dependent kinase 19
SequenceKKIKEDKKNNKEKTGVAGKTGFTLNLLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTTDVFAGCQIPYPKREFLNEDEPEEKAEKNQQQQNQQHQQQPAPQQQQAPQQQNSTQTNGTTGGGGGGTGGGLQHSQDSSLNQGPPNKKPRIGTSGTNSGGPVMGSDYQHSNSRLGYQSNVQGPSQSQSTMGYSSSSQQGSQYTHQSHRY
Length448
PositionKinase
OrganismLatimeria chalumnae (Coelacanth)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Coelacanthiformes> Coelacanthidae> Latimeria.
Aromaticity0.08
Grand average of hydropathy-0.803
Instability index51.21
Isoelectric point9.21
Molecular weight50868.87
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29110
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     125.96|      35|      36|     348|     383|       1
---------------------------------------------------------------------------
  335-  358 (28.06/11.10)	............QHQQQpAPQQ.....QQAPQQQNSTQTNG
  360-  394 (66.86/38.70)	TGGGGGGTGGGLQHSQD.SSLN.....QGPPNKKPRIGTSG
  395-  422 (31.04/10.41)	TNSGGPVMGSDYQHS.N.SRLGyqsnvQGP...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.27|      25|      40|      59|      86|       2
---------------------------------------------------------------------------
   59-   86 (44.55/38.27)	HDLWhiiKFHRASK.ANKKPM.QLP.RGMVK
  100-  127 (34.73/21.42)	HANW...VLHRDLKpANILVMgEGPeRGRVK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29110 with CDK8 domain of Kingdom Metazoa
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