<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29105

Description Mediator complex subunit 23
SequenceRLVCESLINSDSLEWERTQLWALTFKLVRKIIGGADYKGVRDLLKAILEKIQTIPNTVSSAVVQQLIAARDVVEYILERNASLLPAYFAVTEIRKLFPEGKLAHWLLGNLMSDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLRGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEDKFDNGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRTPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFIGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRERTNLKRKLVHAIIGSLKDNRPQGWCLSETYLKCAMNAREDNPWIPDDTYYCKLIGRLLAALPMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVALKSQPLVPRENITAWMNAIGLVITALPEPYWVVLHDRIVNVLNSTTLTSETEWVGYPFHLFDFTACHLSYSEMYCSYVLALAHAVWHHSSIGQLSLIPKFLSEVLKPIVKTEFQLLYVNHLIGPFLQRFHQERTRCMLEIVVAFYEMLQNVDQCSQHLSYMDPICDFLYHVKYMFTGDSVKDQVEKIICNLRPGLKLRLRFITHISKMEPSAPPQAASNASPASQASQVPVNVALPVTQ
Length1277
PositionTail
OrganismLatimeria chalumnae (Coelacanth)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Coelacanthiformes> Coelacanthidae> Latimeria.
Aromaticity0.10
Grand average of hydropathy-0.033
Instability index41.38
Isoelectric point8.25
Molecular weight146018.04
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29105
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     174.70|      52|      95|     968|    1024|       1
---------------------------------------------------------------------------
  968- 1024 (87.79/60.74)	IPdDTYYCKLIGRLLAALpmagKSPGPFPNCDW...RFNEFPNPAAHALH..VTCVELMALA
 1064- 1120 (86.91/47.28)	LP.EPYWVVLHDRIVNVL....NSTTLTSETEWvgyPFHLFDFTACHLSYseMYCSYVLALA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.63|      17|      19|     150|     168|       2
---------------------------------------------------------------------------
  150-  168 (28.23/24.78)	DPTT..LRFPLRglLPYDKDL
  170-  188 (28.40/17.25)	EPQTalLRYVLE..QPYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.76|      10|      19|     885|     896|       3
---------------------------------------------------------------------------
  885-  896 (13.08/12.98)	PVSKSLETLldH
  907-  916 (19.68/11.30)	PVTYLYNTL..H
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     197.90|      57|     262|     418|     479|       4
---------------------------------------------------------------------------
  419-  479 (82.45/74.80)	NCMASGSITPLpMNLLDSLTVhaKMSLIHSIATRVIKLAHAKsSLALAPAL........VE.TYSRLLVY
  497-  559 (79.21/50.29)	NVFKSHAWGIL.HTLLEMFSY..RMHHIQP.HYRVQLLSHLH.SLAAVPQTnqnqlhlcVEsTALRLI..
  709-  738 (36.24/18.73)	...........................INQIGYRVLERIGAR...ALV.AH........VR.TFADFLVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.72|      40|     522|     608|     651|       5
---------------------------------------------------------------------------
  608-  651 (65.73/52.56)	IGSDSIQGTWCKDILQTIMNfTPHN..WASHTLSCFpapLQAFFKQ
 1129- 1170 (64.99/38.73)	IGQLSLIPKFLSEVLKPIVK.TEFQllYVNHLIGPF...LQRFHQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.00|      17|      18|     800|     817|       7
---------------------------------------------------------------------------
  800-  817 (26.13/21.82)	NDFRNRVSDFVKEnSPEH
  821-  837 (34.87/24.03)	NDWHTKHMNYHKK.YPEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.80|      13|      95|     256|     271|      10
---------------------------------------------------------------------------
  256-  268 (23.34/17.60)	PHMVLSLHQKLAG
  276-  288 (24.46/ 9.19)	DHLMWVLLQFISG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29105 with Med23 domain of Kingdom Metazoa
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