<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29079

Description Uncharacterized protein
SequenceINPKFRGHLQSWFKDLIGVKSLMNLCRRFPVFSKKDDLFRTLAEYEVPMVRATWVIKMTSAYHLTQTDAKIKKRAGNDPNLEWTQAICKFLREQLAKLNDGNNSPNTVLSPLNDIETVCSVMNNQYISCLAHHMYSEGLFDRHEFLSWLVEEFECVPLYDEVALSYFVPILQGFIEEVAMNQLLARRMSFAAARHLNWLFLEGSNSRSQSNTPGTPQLITRPTPPQLKQQCPDYLLSIAHTLGCAIQCTVISCPGALVWYQPVDAKSCGSPLDLLPCASSDLPLPDVPKQDVDAEAEIIRRSRASEMKWSTDKCQESTAGHTINRVLGALEALDKQHFERRTTDSWCDPLDSLYHKIFDPGQEKDCDIQLTKSSEDAVVGLLCEWAISPKRLGVHRAAVVAKLLDLRQQAELPEPPMENDTSLNTSESMPPNLASATPYFQNLLFTFLDVQAPELKNRDDFEEIQSFRNLVLLFSELIEHDVFSHDIYMNTLISRGEISSDIFAGDISSLPTYSSTSMDSDPLSNNPSFNRPKRVISLGGMLWDQYQHLLFVYVLVCDDEMKVDDDDQRCVDATPMDFLTTGKSPPNPDGNNIAGGVWGHGQPRHVQYLMHFPIPFQDDGITQEWNQRLMVLYGAGRVKTDVKRAVRKVTRHLTKLMQCRRSIDDAGGVTPGRKAKKSNRSSHLEVLSRYRLLSYFDQHMATSTAAKALLTAIKNYIAGRSSQLPRLEVVQLLFDLMEDALNVGGLVRTAVAVAARLADLAAEIERRKKDFAAQMDYAWYATELSLAVVSVLRHYISYLTLNADITIDAFEGLLNAVKQSCIPKPQRIALHLIGDILVFLYDLHTSFGYIRSQSAESFSGYVSTVRQALCSTKKPATSNCRYDPNFLREFISNPSMESPLTVAQRFSDCLQDVTARYSFVCSAVITVCNGHQDFEKVNALAILCSEMNARCNELSSEWLGVLKALCFSSCAVNFNDVLLVVEASDAQIRDPLSIFTAVLIARGCLSLEDVIQHVAIPSLLAACKNRTAPGLPNPDTSARLTCHLLLQLFKSPSSNNSSFRLPFSSDRHLLAAAQQNIAVGAVLAVLKGVLKLGSINYALKHLALVSYNHYRLVTPITGDAGLSATRNQFSHDHDLSGASLSEFAKHAVRVICSQQWVREKCLKDPVMDLLMDQVLTREQRQNLIQLICYPQEDLQRLSGLSNDPRRYVVNVLSGMTRWTFRQCLLELQVMLRQSPQEKSLPEHIAKATIEVFQQQQQQNAESTKERKSSLTGPELDRCNVWLVAPLVSKLPSQRQGGTSLLNLQPFLTLILTCLKGQDEQRDSLLESLQSQIVMLHTEWQESHRGPCKDISSQNCVHDALELRLSLVGGMFDTVMSNSQWTSDVVIMLMTLILSGMVDVQTNIELFDVVYDMIAVLLHHTLGGDAINRGEGSKREYINIVKKMKKEIADRQSESIRRLRQLLPITRAEVYVVCCEPAGPHMDVKGNKIPVPVDGNQGLQVASKQKLNMWDVIEGLKHSAPLCLAWFGAKTTERKPMFYEEQHSLLLHHQHS
Length1551
PositionKinase
OrganismCiona savignyi (Pacific transparent sea squirt)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Tunicata> Ascidiacea> Phlebobranchia> Cionidae> Ciona.
Aromaticity0.07
Grand average of hydropathy-0.176
Instability index47.32
Isoelectric point6.33
Molecular weight174076.65
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29079
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     372.82|     127|     221|      66|     234|       1
---------------------------------------------------------------------------
   68-  233 (193.26/215.17)	DAKIKKRAGNDPNLewtQAICKFLREQLAKLNDgNNSPNtvLSPLNDIETVCSVMN.....NQYI..SCLAHHMYSEGLFDRHEFLS.WLVEEFECVPLYdevalsyfvpilqgfieevamnqllarrMSFAAARHLNWLFL.....EGS.NSRSQSNTPGTPQ..LITRPTPPQlkqqcPD
  420-  589 (179.56/115.06)	DTSLNTSESMPPNL...ASATPYFQNLLFTFLD.VQAPE..LKNRDDFEEIQSFRNlvllfSELIehDVFSHDIYMNTLISRGEISSdIFAGDISSLPTY.sstsmdsdplsnnpsfnrpkrvislggMLWDQYQHLLFVYVlvcddEMKvDDDDQRCVDATPMdfLTTGKSPPN.....PD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.79|      16|      37|     680|     713|       3
---------------------------------------------------------------------------
  680-  697 (24.23/49.97)	RSSHLEVLSRYRLLsyFD
  720-  735 (28.56/ 8.72)	RSSQLPRLEVVQLL..FD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.65|      26|     484|     821|     963|       4
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  792-  817 (43.63/104.03)	LRHYISYLTLNADITI.DAFEGLLNAV
  887-  913 (42.02/67.97)	LREFISNPSMESPLTVaQRFSDCLQDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.93|      21|      37|     933|     955|       9
---------------------------------------------------------------------------
  933-  955 (26.38/27.79)	DFEKVnALAILCSEMNARcNELS
  973-  993 (34.55/22.70)	NFNDV.LLVVEASDAQIR.DPLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.30|      16|      18|     331|     348|      10
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  331-  348 (24.52/23.57)	EALDKQHFE.RRTTDswCD
  351-  367 (25.78/15.46)	DSLYHKIFDpGQEKD..CD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.14|      37|     954|     370|     407|      11
---------------------------------------------------------------------------
  370-  407 (57.35/40.87)	LTKSSEDAVVGLLCEWAIS...PKRlGVHRAAVVAKLLDLR
 1324- 1363 (60.79/38.97)	LLESLQSQIVMLHTEWQEShrgPCK.DISSQNCVHDALELR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29079 with Med12 domain of Kingdom Metazoa
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