<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29078

Description Uncharacterized protein
SequenceGFYQNRWLIRSRLGPPDVYPQDSKQKEDELTLVNVKQGFINQPPLPEEHSSAHLYTIDVNKVLTFFNQILTQKQMTTTFIDAGAGKRLKPQVSKEHFWLVPVINPKFRGHLQSWFKDLIGVKSLMNLCRRFPVFSKKDDLFRTLAEYEVPMVRATWVIKMTSAYHLTQTDAKIKKRAGNDPNLEWTQAICKFLREQLAKLNDGNNSPNTVLSPLNDIETVCSVMNNQQQSSTYRVSLITCIPRLVQFILTQHNPSVIFKLFPQGLFDRHEFLSWLVEEFECVPLYDEVALSYFVPILQGFIEEVAMNQLLARRMSFAAARHLNWLFLEGSNSRSQSPALQSGSNTPGTPQLITRPTPPQLKQQCPDYLLSIAHTLGCAIQCTVISCPGALVWYQPVDAKSCGSPLDLLPCASSDLPLPDVPKQDVDAEAEIIRRSRASEMKWSTDKCQESTAGHTINRVLGALEALDKQHFERRTTDSWCDPLDSLYHKIFDPGQEKDCDIQLTKSSEDAVVGLLCEWAISPKRLGVHRAAVVAKLLDLRQQAELPEPPMENDTSLNTSESMPPNLASATPYFQNLLFTFLDVQAPELKNRDDFEEIQSFRNLVLLFSELIEHDVFSHDIYMNTLISRGEISSDIFAGDISSLPTYSSTSMDSDPLSNNPSFNRPKRVISLGGMLWDQYQHLLFVYVLVCDDEMKVDDDDQRCVDATPMDFLTTGKSPPNPDGNNIAGGVWGHGQPRHVQYLMHFPIPFQDDGITQEWNQRLMVLYGAGRVKTDVKRAVRKVTRHLTKLMQCRRSIDDAGGVTPGRKAKKSNRSSHLEVLSRYRLLSYFDQHMATSTAAKALLTAIKNYIAGRSSQLPRLEVVQLLFDLMEDALNVGGLVRTAVAVAARLADLAAEIERRKKDFAAQMDYAWYATELSLAVVSVLRHYISYLTLNADITIDAFEGLLNAVKQSCIPKPQRIALHLIGDILVFLYDLHTSFGYIRSQSAESFSGYVSTVRQALCSTKKPATSNCRYDPNFLREFISNPSMESPLTVAQRFSDCLQDVTARYSFVCSAVITVCNGHQDFEKVNALAILCSEMNARCNELSSEWLGVLKALCFSSCAVNFNDVLLVVEASDAQIRDPLSIFTAVLIARGCLSLEDVIQHVAIPSLLAACKNRTAPGLPNPDTSARLTCHLLLQLFKSPSSNNSSFRLPFSSDRHLLAAAQQNIAVGAVLAVLKGVLKLGSINYALKHLALVSYNHYRLVTPITGDAGLSATRNQFSHDHDLSVTSFLKPIGSLDDFDDIHMTGAQDIKRKGASLSEFAKHAVRVICSQQWVREKCLKDPVMDLLMDQVLTREQRQNLIQLICYPQEDLQRLSGLSNDPRRYVVNVLSGMTRWTFRQCLLELQVMLRQSPQEKSLPEHIAKATIEVFQQQQQQNAESTKERKSSLTGPELDRCNVWLVAPLVSKLPSQRQGGTSLLNLQPFLTLILTCLKGQDEQRDSLLESLQSQIVMLHTEWQESHRGPCKDISSQNCVHDALELRLSLVGGMFDTVMSNSQWTSDVVIMLMTLILSGMVDVQTNIELFDVVYDMIAVLLHHTLGGDAINRGEGSKREYINIVKKMKKEIADRQSESIRRLRQLLPITRAEVYVVCCEPAGPHMDVKGNKIPVPVDGNQGLQVASKQKLNMWDVIEGLKHSAPLCLAWFGAKTTERKPMFYEEQHSLLLHHQHS
Length1712
PositionKinase
OrganismCiona savignyi (Pacific transparent sea squirt)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Tunicata> Ascidiacea> Phlebobranchia> Cionidae> Ciona.
Aromaticity0.07
Grand average of hydropathy-0.194
Instability index47.96
Isoelectric point6.58
Molecular weight192389.47
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29078
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     188.33|      50|     225|      45|      99|       1
---------------------------------------------------------------------------
   47-   99 (81.44/66.25)	EEHSSAHLYTidvNKVLTFFNQILTQKQMTTTFIDAGAGKRLKPQ..VSKEHF..WL
  248-  275 (24.47/ 9.36)	......................ILTQHNPSVIF.......KLFPQglFDRHEFlsWL
  277-  325 (82.42/52.06)	EEFECVPLYD...EVALSYFVPIL.QGFIEEVAMNQLLARRMSFA..AARHLN..WL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.05|      40|     225|     327|     367|       2
---------------------------------------------------------------------------
  327-  367 (67.69/64.82)	LEGSNSRSQSPALQS..GSNTPGTPQLI...TRPTPPQLKQQcPDY
  550-  594 (58.36/48.06)	MENDTSLNTSESMPPnlASATPYFQNLLftfLDVQAPELKNR.DDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.79|      16|      37|     813|     846|       3
---------------------------------------------------------------------------
  813-  830 (24.23/38.93)	RSSHLEVLSRYRLLsyFD
  853-  868 (28.56/ 6.58)	RSSQLPRLEVVQLL..FD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.29|      26|     645|     922|     952|       5
---------------------------------------------------------------------------
  922-  952 (35.32/32.39)	VSVLRHYisylTLNADiTIDAFEG....LLNAVKQ
 1574- 1603 (40.97/22.81)	IAVLLHH....TLGGD.AINRGEGskreYINIVKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      52.89|      17|      17|     611|     627|       6
---------------------------------------------------------------------------
  611-  621 (15.70/ 6.61)	.........IEH.DVFSHDIY
  622-  640 (18.38/ 9.12)	MNTLISrgeISS.DIFAGDI.
 1270- 1287 (18.81/ 9.53)	VTSFLK..pIGSlDDF.DDIH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.91|      11|     519|     655|     665|       7
---------------------------------------------------------------------------
  655-  665 (23.58/14.94)	PLSNNPSFNRP
 1185- 1195 (22.33/13.72)	PSSNNSSFRLP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29078 with Med12 domain of Kingdom Metazoa
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