<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29076

Description Uncharacterized protein
SequenceMSLLGFYQNRWLIRSRLGPPDVYPQDSKQKEDELTLVNVKQGFINQPPLPEEHSSAHLYTIDVNKVLTFFNQILTQKQMTTTFIDAGAGKRLKPQVSKEHFWLVPVINPKFRGHLQSWFKDLIGVKSLMNLCRRFPVFSKKDDLFRTLAEYEVPMVRATWVIKMTSAYHLTQTDAKIKKRAGNDPNLEWTQAICKFLREQLAKLNDGNNSPNTSSTYRVSLITCIPRLVQFILTQHNPSVIFKLFPQGLFDRHEFLSWLVEEFECVPLYDEVALSYFVPILQGFIEEVAMNQLLARRMSFAAARHLNWLFLEGSNSRSQSPALQSGSNTPGTPQLITRPTPPQLKQQCPDYLLSIAHTLGCAIQCTVISCPGALVWYQPVDAKSCGSPLDLLPCASSDLPLPDVPKQDLIKHRLLLQQQEAEIIRRSRASEMKWSTDKCQESTAGHTINRVLGALEALDKQHFERRTTDSWCDPLDSLYHKIFDPGQEKDCDIQLTKSSEDAVVGLLCEWAISPKRLGVHRAAVVAKLLDLRQQAELPEPPMENDTSLNTSESMPPNLASATPYFQNLLFTFLDVQAPELSKENRDDFEEIQSFRNLVLLFSELIEHDVFSHDIYMNTLISRGEISSAWTATRYPTIPASTDQRYDSNGYFGESVFSPMDCRVDRHFLDAVRIDSTTGKSPPNPDGNNIAGGVWGHGQPRHVQYLMHFPIPFQDDGITQEWNQRLMVLYGAGRVKTDVKRAVRKVTRHLTKLMQCRRSIDDAGGVTPGRKAKKSNRSSHLEVLSRYRLLSYFDQHMATSTAAKALLTAIKNYIAGRSSQLPRLEVVQLLFDLMEDALNVGGLVRTAVAVAARLADLAAEIERRKKDFAAQMDYAWYATELSLAVVSVLRHYISYLTLNADITIDAFEGLLNAVKHPQTPAHCTSPDRSILVFLYDLHTSFGYIRSQSAESFSGYVSTVRQALCSTKKPATSNCRYDPNFLREFISNPSMESPLTVAQRFSDCLQDVTARYSFVCSAVITVCNGHQDFEKVNALAILCSEMNARCNELSSEWLGVLKALCFSSCAVNFNDVLLVVEASDAQIRDPLSIFTAVLIARGCLSLEDVIQHVAIPSLLAACKNRTAPGLPNPDTSARLTCHLLLQLFKSPSSNNSSFRLPFSSDRHLLAAAQQNIAVGAVLAVLKGVLKLGDAGLSATRNQFSHDHDLSVTSFLKPIGSLDDFDDIHMTGAQDIKRKSGAMEGASLSEFAKHAVRVICSQQWVREKCLKDPVMDLLMDQVLTREQRQNLIQLICYPQEDLQRLSGLSNDPRRYVVNVLSGMTRWTFRQCLLELQVMLRQSPQEKSLPEHIAKATIEVFQQQQQQNAESTKERKSSLTGPELDRCNVWLVAPLVSKLPSQVQGKVLQEASAILEAPQNLSSTSTRSGAGSRSDKDQRQGGTSLLNLQPFLTLILTCLKGQDEQRDSLLESLQSQIVMLHTEWQESHRGPCKDISSQNCVHDALELRLSLVGGMFDTVMSNSQWTSDVVIMLMTLILSGMVDVQTNIELFDVVYDMIAVLLHHTLGGDAINRGEGSKREYINIVKKMKKEIADRQSESIRRLRQLLPITRAEVYVVCCEPAGPHMDVKGNKIPVPVDGNQGLQVASKQKLNMWDVIEGLKHSAPLCLAWFGAKTTERKPMFYEEQHSLLLHHQHSQKRDLKDFLTPPQLPPEEEEDIKPPELKPPIMKYGNSTHTDDIKRPQPKIPKSKRNKRL
Length1747
PositionKinase
OrganismCiona savignyi (Pacific transparent sea squirt)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Tunicata> Ascidiacea> Phlebobranchia> Cionidae> Ciona.
Aromaticity0.07
Grand average of hydropathy-0.277
Instability index50.32
Isoelectric point7.52
Molecular weight196417.78
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29076
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.79|      16|      39|     776|     793|       1
---------------------------------------------------------------------------
  776-  793 (24.23/20.31)	RSSHLEVLSRYRLLsyFD
  816-  831 (28.56/16.42)	RSSQLPRLEVVQLL..FD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.55|      26|      39|    1450|    1476|       2
---------------------------------------------------------------------------
 1450- 1476 (40.57/26.73)	CLKGQDEQRDSLLESLqSQIVMLHTEW
 1492- 1517 (43.98/24.46)	CVHDALELRLSLVGGM.FDTVMSNSQW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.24|      13|      39|    1150|    1162|       3
---------------------------------------------------------------------------
 1150- 1162 (24.48/11.70)	SSFRLPFSSDRHL
 1191- 1203 (24.77/11.92)	SATRNQFSHDHDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.96|      17|      39|     413|     434|       4
---------------------------------------------------------------------------
  413-  434 (21.13/25.72)	RLL.....LQQQEAEiiRRSRASemkW
  450-  471 (26.83/14.87)	RVLgaleaLDKQHFE..RRTTDS...W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.64|      18|      39|     279|     296|       5
---------------------------------------------------------------------------
  279-  296 (30.51/19.91)	PILQGFIEEVAMNQLLAR
  321-  338 (32.13/21.40)	PALQSGSNTPGTPQLITR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.59|      17|      39|     934|     950|       6
---------------------------------------------------------------------------
  934-  950 (30.57/22.73)	YDLHTSFGYIRSQSAES
  975-  991 (32.02/24.24)	YDPNFLREFISNPSMES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.93|      12|      39|    1276|    1287|       7
---------------------------------------------------------------------------
 1276- 1287 (19.55/10.77)	LTR.EQRQNLIQL
 1316- 1328 (16.38/ 7.71)	MTRwTFRQCLLEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.93|      20|      22|    1001|    1022|       9
---------------------------------------------------------------------------
 1001- 1022 (27.04/29.32)	DcLQDVTArYSFVCSAVITVCN
 1026- 1045 (34.89/23.85)	D.FEKVNA.LAILCSEMNARCN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29076 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DLKDFLTPPQLPPEEEEDIKPPELKPPIMKYGNSTHTDDIKRPQPKIPKSKRNKRL
1692
1747










Molecular Recognition Features






MoRF SequenceStartStop




1) LLGFYQNR
2) PEEEEDIKPPELKPPIMKYGNSTHTDDIKRPQPKIPKSKRNKRL
3
1704
10
1747