<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29074
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | METNIDQLVQNVDTDPQTLQSMQQLIQWVADVALYLIASLPMHKQTNRPATSLYWDREWLSMLREMLVVIRVWGLLKSACSPVFNVLDSKMDVLSHMFKLISQLWMANSDEHRMNDLPMSLKSECSMLPFHVVIPPLEPIPPPNSAISQLMNSNAPCSFTFGEAPQDNYVISARQQSMMHVAIPGSSGKIDSLR |
Length | 194 |
Position | Tail |
Organism | Ciona savignyi (Pacific transparent sea squirt) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Tunicata> Ascidiacea> Phlebobranchia>
Cionidae> Ciona.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.054 |
Instability index | 56.57 |
Isoelectric point | 5.43 |
Molecular weight | 21956.27 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP29074
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 116.54| 33| 43| 76| 108| 1
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76- 108 (59.70/35.17) LKSACSPV.FNVLDSKMDVLSHMFKLISQLWMAN
121- 154 (56.83/33.17) LKSECSMLpFHVVIPPLEPIPPPNSAISQLMNSN
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