Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MHHLINEYRPHQARETLKVMMALQKKNMIDVSETLCKNMDKASEILHQCSQELAAMKVKTEASTILPNNSNHSEGIDSMDIGSVLGFDSSSVIDQSNSMMEVDSGYRENSHNEEDTQDEKDIIMCSFVDGMKE |
Length | 133 |
Position | Middle |
Organism | Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Tunicata> Ascidiacea> Phlebobranchia> Cionidae> Ciona. |
Aromaticity | 0.03 |
Grand average of hydropathy | -0.626 |
Instability index | 40.59 |
Isoelectric point | 4.78 |
Molecular weight | 14998.69 |
Publications | PubMed=12481130 PubMed=15114417 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060 |
GO - Cellular Component | core mediator complex GO:0070847 IBA:GO_Central mediator complex GO:0016592 IBA:GO_Central |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central |
Binary Interactions |
Repeats | >MDP29062 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) EGIDSMDIGSVLGFDSSSVIDQSNSMMEVDSGYR 2) IIMCSFVDGMKE 3) MKVKTEAS | 74 122 56 | 107 133 63 |
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