<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29046

Description Mediator complex subunit 23
SequenceMALSMEAQLQSIFEDVVKTVMIEEAFAGMFMDTPEDERTKLISCLGAFRQYWGTLPLESHEQCVQWIVRFIHSQHSPKRISFLYECLAMAVETSLLPPRMVCAALISSDSLEWERTQLWALTFKLIRKIIGGVDYKGVRDLLKALLDKIQTIPTTVSSSIVQQLLAAREVVEYILDRNACLLPAYFAVTEIRKLYPEGQLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPSTLHFPLKGMLPFDKELFEPQTGLLRYVLEQPYSREMVCNMLGLNKQQKQRCPVLEEQLVDLVVYAMERSESEEHFDADVGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLNKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHSFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLGMSDYKIALLCNAYSTNSECFPLPMGALVETIYGNGTMRINLPGTNCMASAAVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKCHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFSRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHENNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMNYHKKYPEKLYFEGLAEQVNPPMQLQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGSLYKFHDRPVTYLYNTLHYYERQLRDRTNLKRKLVHAIMSSLKDNRSPGWCLSETYLKFGINPREDNVWIPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKRENITAWMNAIGLVITALPEPYWIVLHDRIVSVISSPALTSETEWAGYPFALLDFTACHQSYSEMNCSYVLALAHAVWHHSSIGQLSLIPKFLSETLKPIVQTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSFMDPICDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRLRFITHSSIVETSSSAAAATSSSSATSSTPQPPSSSLSTSAAASPSSSQHAHTAM
Length1383
PositionTail
OrganismTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Tetraodontiformes> Tetradontoidea> Tetraodontidae> Takifugu.
Aromaticity0.10
Grand average of hydropathy-0.017
Instability index45.65
Isoelectric point6.95
Molecular weight157550.87
Publications
PubMed=21551351

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29046
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     231.23|      63|     212|     175|     259|       1
---------------------------------------------------------------------------
  175-  240 (102.10/70.98)	LDRNAClLPAYFAVTEI.....RK.LYP.....EGQLSHwlLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGA
  390-  447 (95.59/54.10)	IQKNA..LADFLPVMKL.....FDlLYP.....EKECIP......VPD.INKPQSTHSFAMTCIWIHLNRKAQNDNS
  964- 1007 (33.55/10.59)	...NVC.L.RFLPVFDIvihrfLE.LLPvskslETLLDH..LGSLYK.FHD..RP......................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     603.83|     204|     367|     717|     958|       2
---------------------------------------------------------------------------
  717-  958 (314.26/265.27)	WCkdILQTIMNFT....................................PHNWashTLSCFPAP...........LQAFfkqnNVPQESRFNLKKNV...EEEYRKWksMANENDIITHFsmqgsPPLFlcllWkMLLETdhinqigfRVLERIGARALVAHV....RTFA..DFLVYEFSTSaggQQlnKC..IEILNDMVWKY.NIVTLDrLI...LCLAMRSHENNEAQV..CYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMN.........YHKKYpekLYF.EGLAEQVN.......PPMQLQPQYL
 1048- 1332 (289.57/168.15)	WC..LSETYLKFGinprednvwipddtyyckligrlvdtmagkspgpfpNCDW...RFNEFPNPaahalhvtcveLMAL....AVPGKDVGNALLNVvlkRENITAW..MNAIGLVITAL.....PEPY....W.IVLHD........RIVSVISSPALTSETewagYPFAllDFTACHQSYS...EM..NCsyVLALAHAVWHHsSIGQLS.LIpkfLSETLKPIVQTEFQLlyVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSfmdpicdflYHIKY...MYTgDSVKEQVEkiimtlrPAMKLRLRFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.10|      11|      23|    1341|    1351|       7
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 1341- 1351 (19.01/14.77)	SSSAAAATSSS
 1366- 1376 (20.09/16.12)	STSAAASPSSS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29046 with Med23 domain of Kingdom Metazoa
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