<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29045

Description Mediator complex subunit 23
SequenceSSEGNTKFHLARISGPSPPPSGSLSGSLGACSSSSDESHEQCVQWIVRFIHSQHSPKRISFLYECLAMAVETSLLPPRMVCAALISSDSLEWERTQLWALTFKLIRKIIGGVDYKGVRDLLKALLDKIQTIPTTVSSSIVQQLLAAREVVEYILDRNACLLPAYFAVTEIRKLYPEGQLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPSTLHFPLKGMLPFDKELFEPQTGLLRYVLEQPYSREMVCNMLGLNKQQKQRCPVLEEQLVDLVVYAMERSESEEHFDADVGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLNKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEVMSSLNVFSVTSVHQKTPQRLNIFLVSNCKCFRFLQQSLRNKSLGMSDYKIALLCNAYSTNSECFPLPMGALVETIYGNGTMRINLPGTNCMASAAVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKCHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFSRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHENNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMNYHKKYPEKLYFEGLAEQVNPPMQLQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGSLYKFHDRPVTYLYNTLHYYERQLRDRTNLKRKLVHAIMSSLKDNRSPGWCLSETYLKFGINPREDNVWIPDDTYYCKLIGRLVDNILPYSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLVITALPEPYWIVLHDRIVSVISSPALTSETEWAGYPFALLDFTACHQSYSEMNCSYVLALAHAVWHHSSIGQLSLIPKFLSETLKPIVQTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSFMDPICDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRLRFITHSSIVETSSSAAAATSSSSATSSTPQPPSSSLSTSAAASPSSSQHAHTAM
Length1352
PositionTail
OrganismTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Tetraodontiformes> Tetradontoidea> Tetraodontidae> Takifugu.
Aromaticity0.10
Grand average of hydropathy-0.010
Instability index46.91
Isoelectric point7.58
Molecular weight153388.81
Publications
PubMed=21551351

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29045
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     228.91|      55|     303|     906|     981|       2
---------------------------------------------------------------------------
  157-  197 (39.75/11.10)	NACL..LPAY.FAVTE.IRKLYP.....EGQLSHwlLGSLISdFVDsfRP...........
  927-  981 (98.37/53.05)	NVCLRFLPVFDIVIHR.FLELLPVSKSLETLLDH..LGSLYK.FHD..RPVTYLYNTLHYY
 1219- 1274 (90.80/55.46)	HLVGPFLQRFQQERTRcMLEIGVAFYEMLQAVDQ..HCQHLS.FMD..PICDFLYHIKYMY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.08|      23|      38|     486|     508|       3
---------------------------------------------------------------------------
  458-  476 (19.49/ 8.39)	.....PLPMGaLVETIYGNGTM.RI
  486-  508 (37.86/23.51)	SAAVTPLPMN.LLDSLTVHAKM.SL
  525-  548 (28.73/15.99)	SVALAPALVE.TYSRLLVYMEIeSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.73|      16|     570|     552|     571|       4
---------------------------------------------------------------------------
  552-  571 (27.79/26.58)	GFISQLLPNVFkchaWGILH
 1119- 1134 (29.94/16.80)	GLVITALPEPY....WIVLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.92|      11|     303|     906|     924|       7
---------------------------------------------------------------------------
  888-  898 (22.91/13.20)	NKHMNYHKKY.P
  911-  922 (19.01/12.39)	NPPMQLQPQYlP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     142.00|      43|     304|     308|     350|      10
---------------------------------------------------------------------------
  308-  350 (74.88/56.06)	VGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGL
  614-  656 (67.12/49.31)	VESTALRLITALGSSEVQPQFSRFLSDPKTVLSAESEELNRAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.18|      13|      19|    1086|    1099|      14
---------------------------------------------------------------------------
 1086- 1099 (16.97/15.99)	VPGKDVgNALLNVV
 1106- 1118 (24.20/16.60)	VPRENI.TAWMNAI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29045 with Med23 domain of Kingdom Metazoa
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