<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29040

Description "Transcription elongation factor A (SII), 3"
SequenceMTREEELVRIAKQLDKMVSRNNTDGAMDLLRELKSFNMTLRLLQETRIGVSVNSIRKHCTDEEVIALAKVLIKDWKRLLDAEKQSGMKNGLDSSRAAASPGSSPSETQYRRDSSSSKGSKHSDDGRRDRRESSDSKPGPPLKRNSTESKPERRESSDSKKCSSPPAKKLTAERRESQGSRSSQPGPPQRKPSTDGNERKAKPDTPKSPTTPTSPMSPGGALPPHLNTGDSVRDKCIEMLAAALRTDNDYKEFGTNCDSMAAEIEDHIYQEIKATDMKYKNRVRSRISNLKDPKNPGLRKNVLAGTLALSRIASMSAEEMASDELKQLRNTLTQEAIREHQMAKTGGTSTDLLQCGKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC
Length392
PositionUnknown
OrganismTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Tetraodontiformes> Tetradontoidea> Tetraodontidae> Takifugu.
Aromaticity0.03
Grand average of hydropathy-1.031
Instability index65.65
Isoelectric point9.42
Molecular weight43610.68
Publications
PubMed=21551351

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP29040
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     121.35|      20|      20|     116|     135|       1
---------------------------------------------------------------------------
   99-  113 (27.01/12.53)	SPG.SSPSE..TQYRR...DS
  116-  135 (35.15/18.73)	SKG.SKHSDDGRRDRRESSDS
  138-  158 (29.40/14.35)	GPPlKRNSTESKPERRESSDS
  176-  194 (29.80/14.66)	SQG.SRSSQPGPPQRKPSTD.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.54|      18|      18|     221|     238|       2
---------------------------------------------------------------------------
  221-  238 (33.44/20.80)	LPPHLNTGDSVRD...KCIEM
  239-  259 (26.10/14.84)	LAAALRTDNDYKEfgtNCDSM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.76|      22|      24|     305|     326|       3
---------------------------------------------------------------------------
  305-  326 (34.51/21.62)	TLALS..RIASMSAEEMASDELKQ
  330-  353 (32.24/19.77)	TLTQEaiREHQMAKTGGTSTDLLQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP29040 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AEKQSGMKNGLDSSRAAASPGSSPSETQYRRDSSSSKGSKHSDDGRRDRRESSDSKPGPPLKRNSTESKPERRESSDSKKCSSPPAKKLTAERRESQGSRSSQPGPPQRKPSTDGNERKAKPDTPKSPTTPTSPMSPGGALPPHLNTGDSVRDKCIEMLA
2) IEDHIYQEIKATDMKYKNRVRSRISNLKDPKNPGLRK
81
263
240
299

Molecular Recognition Features

MoRF SequenceStartStop
NANANA