<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29025

Description E1A binding protein p300 b
SequenceMADNVLDSGAPSAKRPKLSSPALSVSASDGNDFGSPFELEQDLPDELISSADLGLSNGGDLSQLHTSLSGPLGGLGLGGQDAASKHKQLSELLRAGAPPQQGVPASNSTAPGAPMGMMGGVGVSPGGPQGMHPHGQPQQPGLMPQVGMVGGVAALSRVAAMMGTQKGNPGQQPHGMMGGQVMNGSPRMGYPGNTGMGNNSNLLADTLQQQQQGGQQMVPGAQMNMMANTGPYAGPYSQSAGQALPGAGLGSPLQNKASMPNMLNQFNVDKKTLPGMVSVGPVGLGPVGVGPSAGPPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSLLNSAGVGLVNSLGAGLPGGQSNNPNLNPPNQIDPSSIERAYAALGLTYQGNQMPQQPSQPNMPTQGLQGQPGMRALNSMGGNSMGVNGGVGVQPPNQQSAVLSNAMLHSNMNAQSLLNDGVANVGSMPTAAPSAAGIRKSWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANTRGEYYHLLAEKIYKIQKELEEKRRTRLQKQGMMPGQPGIPSPGPPQGPPSMGQPPMGPVQPPSKQFLPLLHTDEIVWDLFKFSKYIKLPMPMPPSLPASSPAAQSASNAPGSGTVGSMGPGSASGAGPLPNMSPSTTSTQSNVYPHCPPIRTNSPSPARSLTPQPRQTPPPTIPRSQTPQPQTPGTPQQPPQQQASQQQLLGQTGISEKASQLGAVAASGPQAGPASSVPSQNAHVPLQLPQTPVSKLLHFLYITQPSFLLSPKPSLTADGQVSSPTSVNSSTQPSSLLTTGDGLPPSLEDIKIEVKKQEEKEEEEDQDAHSQKEGKGHLEVKTEEKPEAIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFESEIDPVMQGLGYCCGRKFEFSPQTLCCYGKQLCTIQRDAAYFSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTSINKDQFQRKKNDTLDPELLVECLDCGRKMHQICVLHNETIWPSGFVCDNCLKMSNKTRKENKYSAKRLPQTKLGSYLETRVNDFIKRQNHPESGEVTIRMVHVSDKVVEVKPGMKSRFVDSGEMAESFPYRLKALFAFEDIDGTEVCFFGMHVQEYGSDCPPPNQRRVYISYLDSIHFFKPRHLRTAVYHEILLGYLEYVKRQGYTTGHIWACPPSEGDDYIFHCHPIDQKIPKPKRLQEWYKKMLDQAVSERIVHDYKDVFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENNTSNESTDATDRDSKNAKKKNNKKTSKNKSGLSRANKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAVPTANSLPPITDQDSLMACDLMDGRDAFLTLCRDKHLEFSSLRRSKWSSMCMLVELHSQSQDRFVYTCNECKHHVETRYHCTVCEDYDLCITCYNTKGHVHKMDKLGLGLDDDSNNQAAASTQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKSCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRVGQPAGAPPMGSEVGLPSPGNNGTTAPSTPTSGGTQPPTPQTPTQAMPAAPQQGLGPIAGGQAPASQQQQQQPPPGPPPAAVEIAMRIQQVADAQRKMALQRQAGLMPPHHQQGQGPQMAMGHTGPGGMGASQGLPPQAPAPVAAARAHMDQGQAALMSISQQQGAVGGVQAGAASGATGVAGMVPPGGNIPQAALQELLRTLRSPSSPHQQQQVLNILRSNPQLMAAFIKQRASKYKGGPGGGPGATAGPIVNVMTGGGPQGNMGAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGVGRGLQGQGPQMGNINNPQFREMLIRRQQQQQQQQQQQQQQMVNHVQFQAPQGGPQQPPQAPQPAQSSPAPPSSLLQQQQQQQHLGPGGSPAQHNNPMSPQQPQMSPHPHLQGLANQVRSPQPSPRPQSQPPHSSPSPRLQPQPSPHHISPQMQTGSPHPNHLNQHHPGMVQQNSMEQFGAEQSAMLSQLSSMTGLHRPGGDGQDPLGQNMNHNPLNIM
Length2239
PositionKinase
OrganismTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Tetraodontiformes> Tetradontoidea> Tetraodontidae> Takifugu.
Aromaticity0.05
Grand average of hydropathy-0.711
Instability index67.14
Isoelectric point8.84
Molecular weight243577.78
Publications
PubMed=21551351

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IEA:UniProtKB-SubCell
histone acetyltransferase complex	GO:0000123	IEA:InterPro

GO - Biological Function
histone acetyltransferase activity	GO:0004402	IEA:UniProtKB-UniRule
transcription coactivator activity	GO:0003713	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
rhythmic process	GO:0048511	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29025
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            11|     613.91|      54|      54|    2080|    2133|       1
---------------------------------------------------------------------------
  153-  198 (52.78/10.03)	AA.....LSR.VAAM..........MGTQKGNPGQQ.....PHG..............MMG......GQVMN.G..........S.........P.................R.MGypG.NTG..MG..N
  199-  259 (55.59/11.02)	NSnlladTLQQQ..QQG.GQ...QMVPGAQMNMMAN.....TGP..............YAGPysqsaGQALP.G.........AG.........L.................GsPL..Q.NK...AS..M
  641-  722 (44.89/ 7.25)	PS.....M.....GQPPMGP...VQPPSKQFLPLLH.....TDEivwdlfkfskyiklPMPM.....PPSLP.A.........SS.........PaaqsasnapgsgtvgsmG.PG..S.ASG..AGplP
  723-  779 (58.97/12.21)	NM.....SPSTTSTQSNVYP...HCPPIRTNSP.SParsltPQP..............RQTP.....PPTIPrS.........QT.........P.................Q.P.....QTP..GT..P
 1712- 1763 (53.12/10.15)	QM.....LRRRMASMQRVG.........QPAGA..........P..............PMGS.....EVGLP.S.........PGnngttapstP.................T.SG..G.TQP..PT..P
 1842- 1877 (46.08/ 7.67)	MA.....M.....G..HTGP...GGMGASQGLPPQA.....PAP..............VAAA.....RAHM...................................................D..QG..Q
 1878- 1929 (50.52/ 9.23)	AA.....LMS.ISQQQG.AV...GGVQAGAASGATG.....VAG..............MVPP.....GGNIP.Q.........AA.........L.................Q.EL..L.RTL..RS..P
 1950- 1992 (53.47/10.27)	AA.....FIKQRASKYKGGP...GGGPGATAGPIVN.....VMT..............GGGP.....QGNM...................................................G..AQ..Q
 1993- 2041 (65.57/14.53)	Q........QQQQQQQ...Q...QQQQQQQQQQQQQ.....QQQ..............QQGV.....GRGLQ.G.........QG.........P.................Q.MG..NiNNP..QF..R
 2093- 2156 (83.76/20.94)	SS.....LLQQQQQQQHLGP...GGSPAQHNNPMSP.....QQP..............QMSP.....HPHLQ.GlanqvrspqPS.........P.................R.P...Q.SQPphSS..P
 2157- 2203 (49.16/ 8.75)	SP.....RLQPQPSPHHISPqmqTGSP..HPNHLNQ.....HHP..............GMVQ.....QNS.............................................M..E.QFG..AE..Q
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.79|      31|      34|     410|     442|       2
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  425-  458 (44.51/10.26)	PPNQIDPSSIERAYAALGltyqGNQMP...QQPSQPN
  460-  491 (40.45/ 8.90)	PTQGLQGQPGMRALNSMG....GNSMGvnGGVGVQP.
 1766- 1794 (45.84/12.16)	PTQAMPAAP.QQGLGPIA....GGQAP..ASQQQQ.Q
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.61|      16|      26|      56|      71|       3
---------------------------------------------------------------------------
   28-   46 (20.82/ 6.92)	SDGNDFGspfELEQDLPDE
   56-   71 (27.83/11.62)	SNGGDLS...QLHTSLSGP
   84-   99 (24.96/ 9.70)	SKHKQLS...ELLRAGAPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.34|      16|      23|     928|     947|       4
---------------------------------------------------------------------------
  928-  947 (20.29/21.70)	EKPEAIfkPeeLRQALMPTL
  953-  968 (31.05/16.82)	QDPESL..P..FRQPVDPQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.73|      25|      51|    1270|    1295|       5
---------------------------------------------------------------------------
 1270- 1295 (43.80/28.25)	CpPPNQRRVYISYLDSI..HFFKPRHLR
 1323- 1349 (42.93/22.61)	C.PPSEGDDYIFHCHPIdqKIPKPKRLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     145.76|      20|      35|    1632|    1660|       6
---------------------------------------------------------------------------
  315-  342 (19.57/11.93)	HAH..kcqrReQANgevrqCNLPHCRTMKN
  346-  366 (30.51/16.50)	HMTHC....Q.AGK....sCQVAHCASSRQ
  370-  386 (29.78/ 9.07)	HWKNC....T.RHD.....C..PVCLPLK.
 1633- 1649 (26.55/10.72)	...QC....R.NAN.....CSLPSCQKMKR
 1678- 1697 (39.34/15.85)	HAKHC....Q.ENK.....CPVPFCLNIKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      60.21|      13|      17|    1352|    1364|       7
---------------------------------------------------------------------------
 1352- 1364 (20.58/12.06)	YKKMLDQAVSERI
 1368- 1380 (20.16/11.67)	YKDVFKQATEDRL
 1389- 1401 (19.47/11.01)	FEGDFWPNVLEES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.79|      11|      18|     833|     850|       9
---------------------------------------------------------------------------
  833-  850 (14.96/23.67)	PQTPVSKllhflyiTQPS
  868-  878 (20.83/10.52)	PTSVNSS.......TQPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.99|      27|      36|     505|     531|      10
---------------------------------------------------------------------------
  388-  414 (33.68/16.15)	A.......GDKRNQQSLLNSaGVGLVNS..LGAGLP.
  505-  530 (41.48/21.76)	........HSNMNAQSLLND.GVANVGS..MPTAAPS
  531-  565 (32.84/15.54)	AagirkswHEDI.TQDLRNH.LVHKLVQaiFPTPDPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     265.05|      57|     141|     973|    1029|      12
---------------------------------------------------------------------------
  973- 1029 (102.20/65.40)	DYFDIVKN.PM..DLS.TIKRKLDTGQ..YQEPWQYVDDIW...LMFNNAWLYNRKTSRVYKYCSK
 1032- 1088 (82.07/50.89)	EVFESEID.PVmqGLGyCCGRKFEFSP...QTLCCYGKQLC...TIQRDAAYFSYQ.NR.YHFCEK
 1114- 1176 (80.78/49.96)	DQFQRKKNdTL..DPE.LLVECLDCGRkmHQICVLHNETIWpsgFVCDNCLKMSNKTRKENKYSAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.32|      13|      17|    1209|    1225|      13
---------------------------------------------------------------------------
 1209- 1222 (18.52/20.63)	RMVHvSDKVVEVKP
 1227- 1239 (23.80/ 9.38)	RFVD.SGEMAESFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.22|      19|      30|     101|     121|      14
---------------------------------------------------------------------------
  117-  144 (26.55/ 6.24)	MMGGVgvspggpQGMhPHGQPQQPGlMP
 2062- 2082 (31.67/ 6.72)	MVNHV.......QFQaPQGGPQQPPqAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.71|      20|      34|    1505|    1524|      15
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 1501- 1520 (34.29/20.02)	QDSLMACDLM................DGRDAFLTLC
 1521- 1556 (23.42/11.36)	RDKHLEFSSLrrskwssmcmlvelhsQSQDRFVYTC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29025 with Med12 domain of Kingdom Metazoa
Unable to open file!