<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29015

Description Mediator of RNA polymerase II transcription subunit 15
SequenceMPRASLNPSIPPPNATGAVTSAVGGAAALTQQVPQHSMMSSPSPVQASQSMLPPPQPSPQPPASQPNSASSGPTPSPGGFQPSPSPQPSQSPSNARPVSNYSVPSPGPLNTPGNPSSVMSPAGPTSLEDQQYMEKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLNILTDPTTRCPLKTLQKCEIALEKLKNDMAVPTPPPVATKQQYLCQPLLDAVMTNIRSPVFNHSLYRTFAPAMSAIHGPPISVLPVSSPNICSRKRKPEDEERQSIPNILQGEVARLDAKFLVNLDPSHSSTNGTVHLICKLDDKNLPSVPPLLLRVPADYPEQSPYWAEDGDQYGEWVAYSRGGPSPPVKLSSAPPSQQEPTASCRRSTEP
Length382
PositionTail
OrganismTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-0.607
Instability index90.81
Isoelectric point8.93
Molecular weight41080.22
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29015
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     139.40|      28|      28|      53|      80|       1
---------------------------------------------------------------------------
    2-   30 (30.18/ 6.83)	..PRASLNPSIPPPN.ATGAVTSAVGGaaalT
   53-   80 (60.10/21.59)	PPPQPSPQPPASQPNSASSGPTPSPGG....F
   84-  109 (49.12/16.18)	PSPQPSQSPSNARPVSNYS..VPSPGP....L
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.04|      23|      24|     165|     188|       2
---------------------------------------------------------------------------
  145-  163 (22.25/10.51)	PLRRMINKIDKNEDR..KKDL.....
  165-  188 (35.35/27.22)	KMKSLLNILTDPTTRcPLKTLQK..C
  194-  215 (28.43/15.63)	KLK...NDMAVPTPP.PVATKQQylC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29015 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MPRASLNPSIPPPNATGAVTSAVGGAAALTQQVPQHSMMSSPSPVQASQSMLPPPQPSPQPPASQPNSASSGPTPSPGGFQPSPSPQPSQSPSNARPVSNYSVPSPGPLNTPGNPSSVMSPAGPTSLEDQQYMEKLKQLS
2) WVAYSRGGPSPPVKLSSAPPSQQEPTASCRRSTEP
1
348
140
382










Molecular Recognition Features






MoRF SequenceStartStop




1) QSPYWAEDGDQYGEWVAYSRGGPSPPVKLSS
334
364