<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28962

Description Uncharacterized protein
SequenceXXXXXXXXPGEIPHYQKRHLEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFTGSLDGSGPAGPEGGRLERGENDKHSGKIPVNAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPESHQRLAGPGCKVGLSPTEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRQGARQLHVLVPQSPPTDLPGLTREVTQDDLDRIQASQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length572
PositionUnknown
OrganismPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hominidae> Pongo.
Aromaticity0.04
Grand average of hydropathy-0.941
Instability index63.67
Isoelectric point9.48
Molecular weight61582.22
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28962
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     247.29|      42|      42|      92|     133|       1
---------------------------------------------------------------------------
   92-  129 (57.72/21.88)	...........................................P...P.R.SIHDLKSRNDLQRLPGQ..RLDRLGSRKR.RGDQRDLG
  130-  208 (34.12/ 9.88)	HPGPppkvskashdplvpnssplptngisgspesftgsldgsgP.agP.E.GGRLERGEND..KHSG...KIP.VNAVRP.HTSSPGLG
  209-  235 (27.27/ 6.40)	KPPG.......................................PclqP.KaSV..LQQLDRVDETPGP....................P
  236-  270 (51.67/18.80)	HPKG.......................................P...P.R.C..SFSPRN..SRHEGSfaRQQSLYAPK...G...SVP
  271-  331 (37.85/11.78)	SPSP..................rpqaldatqvpsplplaqpstP...PvR.RLELLPSAES....PVR..WLEQPESHQRlAGPGCKVG
  341-  373 (38.67/12.19)	RAGF.......................................S...P.D.S...SKADSDAASSGGS....D..SKKKK.RYRPRD..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.63|      43|      93|     392|     436|       2
---------------------------------------------------------------------------
  392-  436 (64.21/34.35)	LKERKLTFDPmTRQIKPLTQKEPvRADSPVHMEQQSRTELDKQEA
  487-  529 (72.42/32.06)	LKQEESTRQG.ARQLHVLVPQSP.PTDLPGLTREVTQDDLDRIQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.28|      14|     135|     135|     153|       3
---------------------------------------------------------------------------
  135-  153 (17.67/20.27)	PKVSKASHdplVPnsSPLP
  276-  289 (27.61/12.99)	PQALDATQ...VP..SPLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.41|      16|      16|      59|      74|       6
---------------------------------------------------------------------------
   59-   74 (27.49/13.89)	AHQHEAALRGLAGATG
   76-   91 (29.92/15.69)	ANGGAHNCRPEVGAAG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28962 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQ
2) RQGARQLHVLVPQSPPTDLPGLTREVTQDDLDRIQASQWP
3) XXXXXXXXPGEIPHYQKRHLEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFTGSLDGSGPAGPEGGRLERGENDKHSGKIPVNAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPESHQRLAGPGCKVGLSPTEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGV
389
494
1
446
533
387










Molecular Recognition Features






MoRF SequenceStartStop




NANANA