<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28922

Description Uncharacterized protein
SequenceMTTATPQVMRDRLLQAIDSQSNVCNMVVVIEVISFLETFPITKEVLEETRLGKLINDVRKKTRNADLAKRAKNLLRNWQKLIEPGKGESPSKGLSATSWSFKGASYPSLAAPGTISPSGKTGQELKSRNDFNNCSPGLGKQRKRKHVGDQKRTELLPPKMVQNTLSDKTENSEKVLTNRLDETADPGRNMHVHCALHSEVPEALDNKKVNKIPVHAVKPNAAGCIKSPKTTSLQSKSVLQNPGGQDEALSVGQPKDPSHSLYNHQTPEPEAFVKQTLTQTQNNPNSSFTGIIDSSDVKVSAQPFSIKDSSHLGSQKSTFFHNLAASSCNKAISLLEDDPIINTGKKKRQKYRPKNYIVNLDGHNVEDSSKTVKLKDRSLTFNPLTGQITPTCQKDSLQKEDFTQTHRSELQQSEELKLNALITSNPYRQTDWKALSRSEIIQSYLCQQSNVLTSSDTHIPGAHFFMTELLKKEEHCTKDTKKCHTLISDDPPKDLPGVSREICKEDLSRLQTQHWSGVNGCYDTRGNWYDWTECISLDPSDNESKLNILPYVCLD
Length555
PositionUnknown
OrganismOryzias latipes (Japanese rice fish) (Japanese killifish)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Beloniformes> Adrianichthyidae> Oryziinae> Oryzias.
Aromaticity0.05
Grand average of hydropathy-0.749
Instability index51.06
Isoelectric point8.76
Molecular weight61914.08
Publications
PubMed=17554307

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28922
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     214.46|      69|     275|      64|     208|       1
---------------------------------------------------------------------------
   64-  138 (101.04/138.16)	NADLAKRAKNL.LRNWQKLIEPGkGEspSKGLSATswSFKGASYpSLAAPGTISPSGKTGQEL.KSRNDFNNCSPGL
  221-  291 (113.41/38.21)	AAGCIKSPKTTsLQSKSVLQNPG.GQ..DEALSVG..QPKDPSH.SLYNHQTPEPEAFVKQTLtQTQNNPNSSFTGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.95|      30|      33|     395|     424|       2
---------------------------------------------------------------------------
  394-  423 (47.77/27.84)	KDSLQKEDFTQTHRSELQQSEELKLNALIT
  424-  453 (52.18/30.99)	SNPYRQTDWKALSRSEIIQSYLCQQSNVLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.89|      18|      19|     176|     193|       4
---------------------------------------------------------------------------
  176-  193 (32.12/26.93)	LTNRLDETADPGR..NMHVH
  196-  215 (25.76/19.87)	LHSEVPEALDNKKvnKIPVH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.31|      12|      24|     474|     485|       5
---------------------------------------------------------------------------
  474-  485 (23.73/16.82)	EHCTKDTKKCHT
  501-  512 (20.58/13.56)	EICKEDLSRLQT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28922 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAPGTISPSGKTGQELKSRNDFNNCSPGLGKQRKRKHVGDQKRTELLPPKMVQNTLSDKTENSEKVLTNRLDETADPGRNMHVHCALHSEVPEALDNKKVNKIPVHAVKPNAAGCIKSPKTTSLQSKSVLQNPGGQDEALSVGQPKDPSHSLYNHQTPEPEAFVKQTLTQT
110
280










Molecular Recognition Features






MoRF SequenceStartStop




1) KNLLRNWQKL
2) LPYVCL
3) PKNYIVNLD
72
549
353
81
554
361