<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28916

Description Uncharacterized protein
SequenceMEPPSKPGSNQVADVVFVIEGTANLGPYFESLRKNYILPAIEYFNGGPPAETDFGGDYGGTQYGLVVFNTVDCAPESYVQCHAPTSSAYEFVSWIDSIQFMGGGAESCSLIAEGLSVALQLFDDFKKMREQIGQTHKVCVLLCNSPPYLLPAVESVSYTGCTAESLAKIIRDRGIHFSVVAPRKLPALRSLFERASPLNGAVEPLPDYSQDPFHMVLIRGISLPGEKPHRGRRLCTSLTRQSFCNLMRICPFVQAVCVRQSYPSCFYILNIYKQQPPHLEVKVFCFLKESLFSCCPPAHVSQPKMNPPNISAGPTQAVPPMPHQVPPNQLVPPPGQPTLSQQPQAPLQQQQSANQPTAPSGQPNMVKEDKPVSQNVFNVHFFCFFFPQKPKASSMDSATKLTRSLPCQVHVNQGENLNTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFLFTNKDLDSLRGLYRIMANGFAGCVHFPHTTSPCEVRVLMLLYSSKKKIFMGLIPNDQSGFVNGIRQVITNHKQVQQHRAPGQVPPNQNFLNRAPGPIPVSHGNVQPQSVVVGMPPVSQVSIMEEQQRQNNMVRSGPTNQQSAVSGAPPNQMVQNTQAQPQGPILRLSTPGANPQLRSLLLSQQQPQGGVPHMQGMMSHQGLGQQLVHQAPGGGAQMQGQWRQPMPGQQTAVTTGRRGPVPQTGMQQVSSAMEDDLLMDLI
Length712
PositionUnknown
OrganismOryzias latipes (Japanese rice fish) (Japanese killifish)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Beloniformes> Adrianichthyidae> Oryziinae> Oryzias.
Aromaticity0.07
Grand average of hydropathy-0.303
Instability index55.59
Isoelectric point8.85
Molecular weight78211.94
Publications
PubMed=17554307

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28916
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.27|      22|      23|     634|     656|       1
---------------------------------------------------------------------------
  634-  656 (39.69/13.74)	QQQPQGGvPHMQGMMSHQGLGQQ
  659-  680 (41.58/11.93)	HQAPGGG.AQMQGQWRQPMPGQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.79|      22|      23|     316|     337|       2
---------------------------------------------------------------------------
  316-  337 (45.62/15.30)	QAVPPMPHQVPPNQLVPPPGQP
  342-  363 (34.27/ 9.79)	QPQAPLQQQQSANQPTAPSGQP
  582-  599 (26.76/ 6.16)	NMVRSGPT....NQQSAVSGAP
  605-  625 (29.14/ 7.31)	QNTQAQPQG.PILRLSTPGANP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.90|      26|      28|     503|     529|       3
---------------------------------------------------------------------------
  503-  529 (42.01/27.46)	GLIPNDQSgFVN.GIRQV.ITNHKQVQQH
  533-  559 (42.89/23.25)	GQVPPNQN.FLNrAPGPI.PVSHGNVQPQ
  564-  581 (21.00/ 7.21)	GMPP..........VSQVsIMEEQQRQN.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.21|      25|      97|     270|     298|       4
---------------------------------------------------------------------------
  253-  277 (47.00/20.27)	VQAVC.VRQSYPSCFYILNIY..KQQPP
  281-  308 (39.22/26.11)	VKVFCfLKESLFSCCPPAHVSqpKMNPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     227.21|      54|      55|      57|     111|       5
---------------------------------------------------------------------------
    8-   55 (56.14/30.58)	..GSNQVADVVFvieGTANLGP..YFE.........SLRKNYI..LPAIEYFNGGppAET.DFG
   57-  111 (92.21/60.06)	DyGGTQYGLVVF...NTVDCAPESYVQCHAP....TSSAYEFVSWIDSIQFMGGG..AESCSLI
  113-  169 (78.86/46.26)	E..GLSVALQLF...DDFKKMREQIGQTHKVcvllCNSPPYLLPAVESVSYTGCT..AESLAKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.85|      22|      24|     433|     454|       6
---------------------------------------------------------------------------
  415-  432 (28.46/16.57)	ENLNTEQWP.........QKLIMQLIP
  433-  454 (37.63/24.42)	QQLLTTLGPLFR...N..SRMVQFLFT
  455-  481 (27.76/15.97)	NKDLDSLRGLYRimaNgfAGCVHFPHT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28916 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HKQVQQHRAPGQVPPNQNFLNRAPGPIPVSHGNVQPQSVV
2) PKMNPPNISAGPTQAVPPMPHQVPPNQLVPPPGQPTLSQQPQAPLQQQQSANQPTAPSGQPNMVKED
3) PVSQVSIMEEQQRQNNMVRSGPTNQQSAVSGAPPNQMVQNTQAQPQGPILRLSTPGANPQLRSLLLSQQQPQGGVPHMQGMMSHQGLGQQLVHQAPGGGAQMQGQWRQPMPGQQTAVTTGRRGPVPQTGMQQVSSAMEDDL
523
303
567
562
369
707










Molecular Recognition Features






MoRF SequenceStartStop




NANANA