<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28908

Description Uncharacterized protein
SequenceMDLPGKDTLTVEERSSNVAELLKVLMDINVINGGNNDTAEKMKVHAKNFERALFAKCSSRKEYLDSMKEKVNAMRNTRDTRKKQINSNNMNSNASGVQNVNNNNPNYLSNAMNMNSQTFLNQQAQARQQAAQQLKDRQQQAAAAAVAAQQQAHIQQQGKTQLTPQQQQLINQMKIALIPRELLQRIPNIPKGVNTWQQITELAQQKRLTPHDMQVAKEVYKIHQQLLYKSKLQQHATAVNQQQQQQQQQQQQQPQQQNDMSGTMNNNNATNTNSANNNMNNRNPNELPNVLGQINQLFSQDEQRALLQEAIEACKSFQKTQYGSNMTDANKQNFIRKYINQKALKKIQSIRMAQAAAVNANKLQQQQTQIPQQMAPQMPSQIPPQMLPQVQTQRAAANTNIPPNMSQAQIQAQAQQARINTQQQQQQQQQQQQHQQQQQHQQQHQHQHQQQQQQQQQQQQQQQQQMRPKSAAAIMQLLQPTQRDVEIVKKISSDAARTPLRLSDLTSTIPPNEREEIKRKLQANQQLFAQVSSYAPQVYVFTKSEAFLKEVLKLRIFVKEILEKCSKGIFVVKLDTVDKLIMKYQKYWDSMKIQIIRRQQLIQQQQQELQGGNSLPMANNNNTINDNKPLSQQQRVQGSMQQLQQNREQQQQPPQQWPPVPVQEQNTPAFSPPPPTRKNAPDMMSDKQQPLYMPQKEMNQPSNIVSAGPASAASFTQPKKELTGKATNRSKSTSKKVSPANVSPLSNGKSMTPTINYNGLSPAVNNNLKSTQKSPSPLTVDNNSTQDNAFKKEEDHLQALNSKKLEVISRFKHRQEIFSNSSMDLFLFSLADAMNLNELEIEQPILKFNQSFIDSTNGKKKRKMSKVAQRARERDVVELSIVDSKLLMKSKRDQNAKNDYGIKLSCIGSIFKKLENNNIIGELNNFQTPKTYTAISNNKRQFSEITPEEDVETKKIKLDHPVEDNKGLVDVWNWDFWSND
Length980
PositionTail
OrganismKazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Kazachstania.
Aromaticity0.04
Grand average of hydropathy-1.005
Instability index53.71
Isoelectric point9.77
Molecular weight111988.95
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
RNA polymerase II activating transcription factor binding	GO:0001102	IEA:EnsemblFungi
TFIIE-class transcription factor complex binding	GO:0001095	IEA:EnsemblFungi
TFIIH-class transcription factor complex binding	GO:0001097	IEA:EnsemblFungi
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of invasive growth in response to glucose limitation	GO:2000219	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi
regulation of establishment of protein localization to chromosome	GO:0070202	IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly	GO:0051123	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28908
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.06|      21|      21|     422|     442|       1
---------------------------------------------------------------------------
  239-  259 (38.27/ 9.81)	VNQQQQQQ..QQQQQQQPQ...QQND
  435-  457 (36.48/ 8.99)	QQQQQHQQqhQHQHQQQQQ...QQQQ
  643-  666 (30.32/ 6.17)	LQQNREQQ..QQPPQQWPPvpvQEQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.38|      16|      28|     366|     393|       3
---------------------------------------------------------------------------
  158-  176 (19.97/10.03)	GKTQLtPQQQQliNQM..KIA
  366-  383 (27.41/ 6.25)	QQTQI.PQQMA..PQMpsQIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.14|      21|      26|     738|     758|       5
---------------------------------------------------------------------------
   87-   99 (21.60/ 6.65)	SN..NM..NSN.......ASG.VQN
  738-  756 (28.17/10.92)	....SPANVSPL.SNGKSMTP.TIN
  757-  781 (23.37/ 7.80)	YNglSPAVNNNLkSTQKSPSPlTVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.24|      25|      26|     865|     889|       6
---------------------------------------------------------------------------
  565-  583 (30.81/24.93)	C.....SKGIFVVKLDTVD.KLIMK
  865-  889 (39.63/34.63)	SKVAQRARERDVVELSIVDSKLLMK
  890-  909 (26.80/20.52)	SKRDQNAKNDYGIKLSCIGS.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.70|      46|     264|      17|      75|       9
---------------------------------------------------------------------------
   17-   75 (69.33/66.44)	NVAELLKVLMDINvinggnndtaekmKVHAKNFERALFAK....CSS..RKEYLDSMKE..KVNAMR
  283-  336 (67.37/40.99)	NPNELPNVLGQIN.............QLFSQDEQRALLQEaieaCKSfqKTQYGSNMTDanKQNFIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.58|      16|     209|     141|     156|      10
---------------------------------------------------------------------------
  141-  156 (26.90/14.85)	AAAAAVAAQQQAHIQQ
  342-  354 (18.99/ 7.73)	KALKKI...QSIRMAQ
  416-  426 (19.69/ 8.37)	Q..ARINTQQQ...QQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.74|      17|     162|     101|     117|      11
---------------------------------------------------------------------------
  101-  117 (33.13/19.67)	NNNNPNYLSNAMNMNSQ
  266-  282 (31.61/18.37)	NNNATNTNSANNNMNNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.21|      20|      23|     190|     211|      12
---------------------------------------------------------------------------
  190-  211 (31.56/20.95)	PKGVNTWQQitELAQQKRLTPH
  216-  235 (33.65/16.72)	AKEVYKIHQ..QLLYKSKLQQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.04|      17|      28|     480|     507|      13
---------------------------------------------------------------------------
  480-  497 (25.04/39.69)	PTQRDvEIVKK..........ISSDAAR
  511-  537 (23.00/ 6.23)	PNERE.EIKRKlqanqqlfaqVSSYAPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.26|      13|      19|     668|     685|      14
---------------------------------------------------------------------------
  668-  680 (24.18/ 7.51)	PAFSPPPPTRKNA
  690-  702 (23.08/16.24)	PLYMPQKEMNQPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.51|      10|      28|     815|     824|      17
---------------------------------------------------------------------------
  815-  824 (18.63/11.12)	QEI..FSNSSMD
  843-  854 (14.88/ 7.39)	QPIlkFNQSFID
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28908 with Med15 domain of Kingdom Fungi
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