<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28854

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKNLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRTPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTSENEIITHFSAQGSSPLFLCLLWKMLLDTDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEGHLRDRTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNPREENPWVPDDAYYCKLIGRLLANLQGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDCIVNVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEALIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADRYSSHLNYMDPICDFLYHMKYMFTGDSVKDQVEKIICNLRPALKLRLRFITHISKMEPAAVSQQPLSSGSPAQQPSQVPVNVALPVTQ
Length1370
PositionTail
OrganismTaeniopygia guttata (Zebra finch) (Poephila guttata)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Passeroidea> Estrildidae> Estrildinae> Taeniopygia.
Aromaticity0.10
Grand average of hydropathy-0.029
Instability index45.63
Isoelectric point7.19
Molecular weight156805.34
Publications
PubMed=20360741

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP28854
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.96|      16|      16|     995|    1010|       1
---------------------------------------------------------------------------
  995- 1010 (31.70/21.40)	YKFHDRPVTYLYNTL.H
 1012- 1028 (25.26/15.48)	YEGHLRDRTNLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     219.22|      52|     299|     847|     968|       2
---------------------------------------------------------------------------
  188-  230 (42.70/12.10)	........RKLYPEgKLPHWLLGNLVSDFVDtFRP...TARINSICGRcsLLPV..
  917-  968 (100.03/109.63)	WHTKHMSYHKKYPE.KLYFEGLAEQVNPPVQ.IQPQYLPIYFGNVCLR..FLPVFD
 1216- 1260 (76.49/16.79)	WHHSSIGQLSLIPK....F..LTEALIPIVK.TEFQLLYVY..HLVGP..FLQRFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.30|      30|      85|    1029|    1061|       3
---------------------------------------------------------------------------
 1029- 1061 (49.99/41.14)	AIIGSLKDnrPLgW.CLSDTYLKCAMNP..REENPW
 1151- 1183 (47.30/27.75)	LIITALPE..PY.WiVLHDCIVNVINSPslTSETEW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.27|      17|     299|     262|     336|       4
---------------------------------------------------------------------------
  243-  261 (28.00/13.01)	LDPTT..LRFPLKglLPYDKD
  263-  281 (28.27/86.83)	FEPQTalLRYVLE..QPYSRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.65|      15|      30|     490|     505|      10
---------------------------------------------------------------------------
  490-  505 (23.45/22.22)	LPMGvLVETIYGNGNM
  523-  537 (26.20/18.90)	LPMN.LLDSLTVHAKM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      32|     339|     348|      12
---------------------------------------------------------------------------
  339-  348 (18.69/11.21)	IFFVLFQFAS
  372-  381 (19.45/12.00)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.54|      17|     462|     634|     650|      15
---------------------------------------------------------------------------
  634-  650 (31.77/22.34)	PQTNQNQLHL.CVESTAL
 1098- 1115 (27.77/18.44)	PNPAAHALHVtCVELMAL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28854 with Med23 domain of Kingdom Metazoa

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