<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28823

Description Uncharacterized protein
SequenceSLAPLAPGDMSGTAAAGLRPQSNLRKMVAVLEVISSLRKYPITKETLEEKGLGKLVDVSKQSKKQGAAKWAKKLLQSSWSQCPGSRRSLAAPRDGRLGRWRRSQLLAKGGSGGPPKTVHDVKNPKGLQALPGQTPAPEEASDLVDPRPLPKVSRSSHNALVPNSHTSGILCSLEGRGQAHPQDNLLEHNVHDQQSSEIPVKPGRPHSSSPSPGQPPGPCLQEKAVLQQQHRGDKTPCLPPPKCPLHCSVSPGNSLLEPSFAGQQSSDSPWVLCLAPLPLLGSRHSMPGSVFMLLPAQPSCPPPPRGGQVRHREQPQGHHGLAAPGCKAGCWPQQQSLSPGDSPSGLLQGSGAVSSGGSDSTKKRYQPREYTVDLVRQAIEVNIMPVGFKRVETGHHGMMRHIKPPTQKQPARTDGPVHPKQSSTELDRQEAEAKAPLQSPFRQTEWTELWHREIIPDIPRYPGHTSVPRRRITCCHRLACRPQGPAPSLPVPEAGREHLARTKKLQVLLSQDRPIDLPGLTQKITQDNLNRILARQWPGVNGCQDTQGNWYHWTQCIWVDWEDDCRPLSIQLCLL
Length575
PositionUnknown
OrganismOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Strepsirrhini> Lorisiformes> Galagidae> Otolemur.
Aromaticity0.04
Grand average of hydropathy-0.684
Instability index74.26
Isoelectric point9.56
Molecular weight62719.79
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28823
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     265.05|      58|     159|     130|     187|       1
---------------------------------------------------------------------------
  130-  187 (99.80/39.44)	LPGQ..TPAPEEASDLVDPRPLPKVSRSSHNALVPNSHTSGILCSLEGRGQAHPQDN...LLE
  211-  257 (84.53/32.24)	SPGQ..PPGPC....LQEKAVLQQQHRGDKTPCLPPPKCP.LHCSV......SPGNS...LLE
  294-  348 (80.73/30.45)	LPAQpsCPPPPRGGQ.VRHREQPQ....GHHGLAAPGCKAG..CWPQQQSLS.PGDSpsgLLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     221.32|      56|      67|     394|     449|       2
---------------------------------------------------------------------------
  361-  392 (31.13/ 9.50)	...................TKKRYQPREYTVDLVRQAIEVNI.MPVGFKRVE....
  394-  449 (98.24/45.03)	GHHGMMRHIKPPTQKQPARTDGPVHPKQSSTELDRQEAEAKAPLQSPFRQTEWTEL
  463-  517 (91.95/41.71)	GHTSVPRRRITCCHRLACRPQGPA.PSLPVPEAGREHLARTKKLQVLLSQDRPIDL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28823 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AGCWPQQQSLSPGDSPSGLLQGSGAVSSGGSDSTKKRYQPREYT
2) PVGFKRVETGHHGMMRHIKPPTQKQPARTDGPVHPKQSSTELDRQEAEAKAPLQSPFR
3) QCPGSRRSLAAPRDGRLGRWRRSQLLAKGGSGGPPKTVHDVKNPKGLQALPGQTPAPEEASDLVDPRPLPKVSRSSHNALVPNSHTSGILCSLEGRGQAHPQDNLLEHNVHDQQSSEIPVKPGRPHSSSPSPGQPPGPCLQEKAVLQQQHRGDKTPCLPPPKC
4) VFMLLPAQPSCPPPPRGGQVRHREQPQGHHGLAAPGC
328
385
81
290
371
442
243
326










Molecular Recognition Features






MoRF SequenceStartStop




1) AAKWAKKLLQ
2) RLGRWRRSQLLAKG
67
96
76
109