<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28821

Description Uncharacterized protein
SequenceIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEAALRGLAGAAGSANGGAHNCRPEVGVAGTPKSIHDLKNRNDIQRLPGQRLDRLGTRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGIGGSPESFPSPLDGSGHMGPEGSRLERENDKHSGKIPVNAVRPHTNSPGLSKPSGPCLQGKASVLQQQDRVDETPGLPHPKGLPRCSFSPRNSRHEGSFARQQSSYAPKGSVPSPSPRPQALDAMQVPSPLELLPSAESPVRWLEQPEGHQRPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQPRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKLHVLVPHDPPTDLPGLTREVTQDDLDRIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNVLPYVCLD
Length547
PositionUnknown
OrganismOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Strepsirrhini> Lorisiformes> Galagidae> Otolemur.
Aromaticity0.04
Grand average of hydropathy-0.909
Instability index55.07
Isoelectric point9.39
Molecular weight60220.93
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28821
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     239.59|      42|      44|     133|     174|       1
---------------------------------------------------------------------------
  133-  174 (79.48/30.25)	GH...P.GPP.....P...K..VSK.........AS..HD.P..LVPNSSPLP.TNGIGGSPESFPSPLDG
  176-  220 (48.73/16.07)	GH...M.GPE....gS...R..LER.........ENdkHS.G..KIPVNAVRPhTNSPGLSKPSGPC.LQG
  238-  293 (40.68/12.36)	PH...PkGLPrcsfsP...R..NSRhegsfarqqSS..YA.PkgSVPSPSPRP.Q...ALDAMQVPSPLEL
  295-  331 (38.05/11.15)	PS...A.ESP.....V...RwlEQP.........EG..HQrP..LLPRA.........GFSPDSSKADSDA
  356-  396 (32.67/ 8.66)	GQvaeA.GVK.....PvrlK..ERK.........LT..FD.P..MTRQIKPLT.QK....EPVRADSP...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.96|      13|      22|     436|     450|       3
---------------------------------------------------------------------------
  436-  450 (17.34/15.87)	YLSRQSSllSSSGAQ
  461-  473 (22.62/13.53)	YLKQEES..TRRGAR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28821 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EAALRGLAGAAGSANGGAHNCRPEVGVAGTPKSIHDLKNRNDIQRLPGQRLDRLGTRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGIGGSPESFPSPLDGSGHMGPEGSRLERENDKHSGKIPVNAVRPHTNSPGLSKPSGPCLQGKASVLQQQDRVDETPGLPHPKGLPRCSFSPRNSRHEGSFARQQSSYAPKGSVPSPSPRPQALDAMQVPSPLELLPSAESPVRWLEQPEGHQRPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQPRTELDKQEAKASLQSPFEQTNW
2) RRGARKLHVLVPHDPPTDLPGLTREVTQDDLDRIQAHQWP
67
469
424
508










Molecular Recognition Features






MoRF SequenceStartStop




1) KKKKRYRPRDYTVNLD
340
355