<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28820

Description Uncharacterized protein
SequenceTAALPSPQQMRDRLLQAVDAQSNIRDTATVLEVISILETYPITKKALEDTRLGRVINNVRKQSQNQEVAQRAKKLLRSWQKFLEPLPRDEVEPRRPAGAAGRVDGGAPDCRPRVGSAGPGKTLGGAKNPQDLRAPPDERLEKEECHKRRQTKSDVASPGPLPKVPRSSREPLVPSSSPLTTGGIPGPHSSSGRAHQEDRQWKPNARDGRRGKSPVKEARPRTGSAGRGQTPGPCLQEKAEVLQQQPRGDKTPCPPQPKRPLDCSFRPGKSPLGHSSAGPQSSRAPRTSVPIPSPLTQVLHAGQVSPSQPSMPTKRRTHMPATGERPAPCLEQAQGHQGLAGTGLKAELSPEAAEPLLPGPGSRLDSRKGDRAFSSSGGSDNTKGRHRPHEGTVKMAGQGAQANEEPVQLKKRKLSFDPVTRQVKTLTQKQPERTDSPVQAERPRAELERPEAKAKAKASLPSPFQQRKGKELSAKEMIPSDLHLQISPLPSWSSSSLHAPGARPLVPQYLKQEENTRPGAPKQQVLVPQAPHTDLPGLTREVTRDDVHRIQACQWPGVNGCQDTQGNWYNWTQCMSVDREDGSGPLTILPYVCLD
Length595
PositionUnknown
OrganismOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Strepsirrhini> Lorisiformes> Galagidae> Otolemur.
Aromaticity0.03
Grand average of hydropathy-0.950
Instability index65.70
Isoelectric point9.92
Molecular weight64656.18
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28820
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.08|      16|      17|     202|     217|       1
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  202-  217 (24.50/ 7.20)	KPNARDGRRGKSPVKE
  245-  257 (22.54/ 6.01)	QP..R.GDKTPCPPQP
  259-  274 (26.04/ 8.14)	RPLDCSFRPGKSPLGH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.37|      15|      15|     448|     462|       3
---------------------------------------------------------------------------
  448-  462 (24.22/12.11)	ERPEAKAKAKASLPS
  466-  480 (25.15/12.81)	QRKGKELSAKEMIPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     366.38|      85|     183|     108|     192|       5
---------------------------------------------------------------------------
   41-   92 (52.55/16.23)	............................................PITKKALEDTRLGRVINNVRKQSQNqEV...............................AQRA..KKLLRSWQKF..L.....EPLPRDEVE.......
  108-  192 (157.48/62.62)	PD.................C....RPRVGSAG..PGKTLGGAKNPQDLRAPPDERLEKEECHKRRQTKS.DV...............................ASPGPLPKVPRSSREP..LVPS.SSPLTTGGIPGPHSSSG
  199-  308 (70.56/24.19)	RQwkpnardgrrgkspvkeA....RPRTGSAG..RGQTPG....PC.LQ.......EKAEVLQ.........qqprgdktpcppqpkrpldcsfrpgksplghSSAG..PQ...SSRAPrtSVPI.PSPLTQVLHAGQVSPSQ
  309-  377 (85.79/30.93)	PS.................MptkrRTHMPATGerPAPCLEQAQGHQGL.......................................................AGTGLKAELSPEAAEP..LLPGpGSRLDSRKGDRAFSSSG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28820 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FLEPLPRDEVEPRRPAGAAGRVDGGAPDCRPRVGSAGPGKTLGGAKNPQDLRAPPDERLEKEECHKRRQTKSDVASPGPLPKVPRSSREPLVPSSSPLTTGGIPGPHSSSGRAHQEDRQWKPNARDGRRGKSPVKEARPRTGSAGRGQTPGPCLQEKAEVLQQQPRGDKTPCPPQPKRPLDCSFRPGKSPLGHSSAGPQSSRAPRTSVPIPSPLTQVLHAGQVSPSQPSMPTKRRTHMPATGERPAPCLEQAQGHQGLAGTGLKAELSPEAAEPLLPGPGSRLDSRKGDRAFSSSGGSDNTKGRHRPHEGTVKMAGQGAQANEEPVQLKKRKLSFDPVTRQVKTLTQKQPERTDSPVQAERPRAELERPEAKAKAKASLPSPFQQRKGKELSAKEMIPSDLHLQISPLPSWSSSSLHAPGARPLVPQYLKQEENTRPGAPKQQVLVPQAPHTDLPGLTREVT
82
543










Molecular Recognition Features






MoRF SequenceStartStop




1) CLQEKAEVLQQQ
2) PTKRRTHMPAT
3) VQLKKRKLSF
234
312
407
245
322
416