<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28801

Description Transcription elongation factor A2
SequenceMGKEEEIARIARRLDKMVTKKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLLEGTRSPRGGGGRARVPQEDRRRQREEAEPLKPLRTKGQPLAKATVDASDAKTRERGRGMPLPTSSSKDASEAVDPSRKRSEMPRMPSTPRITTFPPVPVTCDAVRNKCREMLSAALQTDHDHVAIGADLERLSAQIEEYILCDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCSKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKFC
Length344
PositionUnknown
OrganismOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Strepsirrhini> Lorisiformes> Galagidae> Otolemur.
Aromaticity0.03
Grand average of hydropathy-0.730
Instability index61.67
Isoelectric point9.60
Molecular weight38589.00
Publications









Function






Annotated function


GO - Cellular Component
centrosome	GO:0005813	IEA:Ensembl
nucleoplasm	GO:0005654	IEA:Ensembl

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28801
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.91|      24|      27|     291|     314|       1
---------------------------------------------------------------------------
  291-  314 (45.60/29.39)	HQMARTGGTQ.TDLFTCSKC..RKKNC
  318-  344 (37.31/22.88)	QVQTRSSDEPmTTFVVCNECgnRWKFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.53|      15|      20|     125|     139|       2
---------------------------------------------------------------------------
  125-  139 (29.30/17.60)	DASDAKTRERGRG.MP
  147-  162 (21.23/10.79)	DASEAVDPSRKRSeMP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.65|      21|      27|     164|     184|       3
---------------------------------------------------------------------------
  164-  184 (39.61/22.73)	MPSTPRITTFPPVPVTCDAVR
  190-  210 (35.04/19.48)	MLSAALQTDHDHVAIGADLER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.47|      37|      40|      10|      49|       4
---------------------------------------------------------------------------
   13-   49 (59.01/43.13)	RLDKMVTKKSAEGAMDLLREL.KAMPVTLHLLQSTRVG
   51-   88 (54.46/31.64)	SVNALRKQSSDEEVIALAKSLiKSWKKLLEGTRSPRGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.22|      12|      18|     220|     232|       5
---------------------------------------------------------------------------
  220-  232 (18.92/16.01)	LCDVGNTDMKyKN
  241-  252 (21.30/12.09)	LKDAKNPDLR.RN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28801 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KLLEGTRSPRGGGGRARVPQEDRRRQREEAEPLKPLRTKGQPLAKATVDASDAKTRERGRGMPLPTSSSKDASEAVDPSRKRSEMPRMPSTPRITTFPPVPV
77
178










Molecular Recognition Features






MoRF SequenceStartStop




1) LIKSWKKLLEG
71
81