<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28797

Description Mediator complex subunit 25
SequenceMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGYTTESLVQKIVQRGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPADVSQDPRHMVLVRGLVLPVGGGSASGPLQPKQPVPLPPTAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINALQQAAPGVGPPFSQAPAPPLPPGPPGAPKPPPASQPSLVSTVATGPGLAPPAQPGAASMAGTVAPGGVSGPSPAQLGAPALSGQQSVTNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGGQQAPPGLGPILEDQPRPSQNLLQLRPPQPQNQGTVGASGATGQPQPQGTTQPPPGAPQGPPGAAPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPSRAPLPGQMLLSGAPRGPVPQPGLQPSVMEDDILMDLI
Length746
PositionUnknown
OrganismOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Strepsirrhini> Lorisiformes> Galagidae> Otolemur.
Aromaticity0.05
Grand average of hydropathy-0.241
Instability index58.17
Isoelectric point8.86
Molecular weight78170.89
Publications









Function






Annotated function


GO - Cellular Component
nucleoplasm	GO:0005654	IEA:Ensembl

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28797
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     462.50|      62|      62|     209|     270|       2
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  198-  253 (93.58/21.52)	.....AA..PPALLEPLQ.........P........PADVS..QD........PRHMVLVRGLVL.....PVGGGSASGP.LQPK...................Q..PV.PLP...PTAP.S
  254-  315 (66.80/13.18)	GATLSAA..PQQPLPPVPP.....qyqV........PGNLSaaQ.............VAAQNAVE.....AAKNQKA.G..LGPR..................fS..PInALQ...QAAP.G
  317-  366 (76.63/16.24)	GPPFSQA..PA...PPLPP.......gP........PGAPK..PP........PASQ...PSLVS.....TV....ATGPgLAP..........................PAQ...PGAA.S
  367-  435 (62.22/11.76)	MAG.TVA..PGGVSGPSPA....qlgaP........ALSGQ..QS........VTNKLLAWSGVLewqekP.KPASVDAN.TKLT...................R..SL.PCQ...VYVN.H
  436-  506 (56.43/ 9.95)	GENLKTEqwPQKLIMQLIPqqllttlgPlfrnsrmvQFHFT..N..........KDLESLKGLYR.....IMGNGFA.GC............................V.HFP...HTAP.C
  557-  639 (62.15/11.73)	GMGGQQA..P.PGLGPILE........D........QPRPS..QNllqlrppqPQN....QG........TVGASGATGQ.PQPQgttqpppgapqgppgaapgP..PP.PGPilrPQNP..
  676-  714 (44.68/ 6.29)	............AL..LPP........P........HQGLG..Q.........PQ...LGPPLLH.....P........P...PA...................QswPA.QLP...SRAPlP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28797 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSASGPLQPKQPVPLPPTAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINALQQAAPGVGPPFSQAPAPPLPPGPPGAPKPPPASQPSLVSTVATGPGLAPPAQPGAASMAGTVAPGGVSGPSPAQLGAPALS
2) HKQVQQQKLEQQRGMGGQQAPPGLGPILEDQPRPSQNLLQLRPPQPQNQGTVGASGATGQPQPQGTTQPPPGAPQGPPGAAPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPSRAPLPGQMLLSGAPRGPVPQPGLQPSVMEDDILMD
233
544
390
744










Molecular Recognition Features






MoRF SequenceStartStop




NANANA