<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28775

Description Uncharacterized protein
SequenceAVEVWSDDKCVDKGNDGWDATTGSQCGGAAVSAVQGYGEQAHLCKPEPQKTFSVFQDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGVGDEGLKARKNKQESFPTLETVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLGKILSDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSNHVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADAEPGARMTCRLLLHLFRAPQACFLPQAAGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVSSLKNEEFAMRSLRRDGNADDIWTASQTVKSCGKSISIETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTDGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLNNNSSNPGMSLFNPNSIGSAEASSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQDDTKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTRDVIACEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRMDRKVIKYEEQHHLLLYHTHPMPKPRSYYLEPLPLPPEEEEEEPTSPISQEPERKSAELSDQGKTTADEEKKTKGRKRKTKSSSRVDEYPQSNIYRVPPNYSPISSQMMHHPQSTLWGYNLMGQPQQPGFFLQNQSLTPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMMQPPSLHAITSQQQLIQMKLLQQQQQQRLLRQAQARPFQQGQPGDQAAVFATQARPSPQLPQYPGLQQAQTMPQGYTMYGTQMPLQQTAQQQAGGLVLSPSYNSRVYPTAHSSPALMERLRQIQQQPSGYVQQQASPYLQPLTSSQRLNHQALQQSPLVAGGIDAVLTSAHPSLPSVPLPQDPMRPRQPQARQQQRLLQPPPQPQQPQQPPQPQQTSQTQNQTLGLQAMQPQQPLFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQQGVAPYGHSSHF
Length1486
PositionKinase
OrganismCavia porcellus (Guinea pig)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Caviidae> Cavia.
Aromaticity0.06
Grand average of hydropathy-0.462
Instability index60.47
Isoelectric point8.22
Molecular weight165472.26
Publications
PubMed=21993624

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28775
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     236.89|      26|      26|    1387|    1412|       1
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 1220- 1245 (24.85/ 6.04)	.QQL.IQMK.L..LQQQQQ.......Q......RLLrQA...QARPF
 1268- 1299 (33.14/10.48)	PQYP.GL.Q.Q..AQTMPQgytmygtQ......MPL.QQ...TAQQQ
 1315- 1339 (27.89/ 7.67)	PTAH.SSPAlM..ERLRQI.......Q......Q...QP...SGYVQ
 1341- 1367 (28.61/ 8.05)	QASPyLQPL.T..SSQRLN.......H......QAL.QQ...SPLVA
 1387- 1412 (54.27/21.80)	PQDP.MRPR.Q..PQARQQ.......Q......RLL.QP...PPQPQ
 1414- 1436 (37.17/12.64)	PQQP.PQPQ.Q..TSQTQN.......Q......TL.......GLQAM
 1438- 1474 (30.97/ 9.31)	PQQP.LFPR.QglQQTQQQ.......QqtaalvRQL.QKqlsSNQPQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.02|      23|      28|     456|     479|       2
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  449-  463 (19.47/ 8.26)	.........LPSLLAA..ACGDADAE
  464-  489 (35.80/27.81)	PGARMTCRlLLHLFRApqACFLPQAA
  494-  508 (22.76/11.44)	PGIRSSCD..RHLLAA..A.......
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.12|      21|      27|     870|     896|       3
---------------------------------------------------------------------------
  657-  685 (31.50/13.96)	QNLEQWTLRQSWLELQLMIkqclkdpgSG
  876-  896 (38.61/35.65)	QRSTQWTTDWALLLLQIIT........SG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.17|      16|      27|     205|     221|       4
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  205-  221 (22.97/18.15)	LLLKSSSLAGSYtTGLC
  235-  250 (29.21/18.28)	LILNPDQTAQVF.EGLC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.83|      17|      28|     791|     807|       5
---------------------------------------------------------------------------
  791-  807 (27.67/14.85)	KERDRQKQKSMSLLSQQ
  818-  834 (26.16/13.64)	KGQDEQREGLLTSLQNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.41|      25|      28|    1056|    1080|       6
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 1056- 1080 (45.59/26.70)	THPM...PKPRSYYLEPLPLPPEEEEEE
 1082- 1109 (32.30/16.61)	TSPIsqePERKSAELSDQGKTTADEEKK
 1123- 1140 (23.52/ 9.95)	VDEY...PQSNIYRVPPNYSP.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.28|      10|      35|     600|     613|      10
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  600-  613 (16.51/16.11)	HCLKEperlCTDKE
  636-  645 (19.77/ 8.55)	HGIKE....CTDGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.76|      12|      30|      73|      84|      11
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   73-   84 (22.32/14.53)	GVGKERDEARHQ
  105-  116 (21.44/13.67)	GVGDEGLKARKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.09|      12|      44|     223|     234|      13
---------------------------------------------------------------------------
  223-  234 (25.00/18.47)	CIVAVL.RRYHSC
  268-  280 (20.08/13.29)	CILAYLyDLYVSC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.91|      31|      37|    1149|    1180|      14
---------------------------------------------------------------------------
 1149- 1180 (54.21/31.86)	PQSTLWGYNLMGQpQQPGFFLQNQSLTPGGSR
 1189- 1219 (54.70/27.68)	PTNTKQALSNMLQ.RRSGAMMQPPSLHAITSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.35|      36|     250|     736|     784|      15
---------------------------------------------------------------------------
  736-  784 (48.35/58.71)	TRQNGIKTFLSSSERRGvwlvapliarLPTSVQGRVlkaAGEELEKGQH
  988- 1023 (63.01/41.38)	TKGNKIAGFDSIDKKQG..........LQVSTKQKV...SPWDLFEGQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.17|      21|      27|     518|     539|      17
---------------------------------------------------------------------------
  518-  539 (30.82/23.74)	FAvLKAIMMLGDAK...IGSNNVSS
  545-  568 (30.35/18.37)	FA.MRSLRRDGNADdiwTASQTVKS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28775 with Med12 domain of Kingdom Metazoa
Unable to open file!