<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28768

Description Uncharacterized protein
SequenceDSCKVQDKKTASNRPSTTISGQNSSHSGNKPDPPPVLRVDDRQRLARERREEREKQLAAREIVWLEREERARLHYEKHLEERKKRLEEQRLKEERRRAAVEEKRRQRLEEDKERLEAVVRRTMERSQKPRQKYNRWSWGGPLHGSPRIHSSDPDRRSVSTMNLSKHVDPVISKRLSSSSATLLNSPDRARRLQLSPWESNVVNRLLTPTHSFLARSKSTAALSGDAVIPICPRSASCSPIIMPYKAAHSRNPVDRPKFFVTPPEGSARRRTVHGTTGHKRDRENVPFHLTSGIRRTLSPANPKARSPASSRLWLPSKSLPHLPGTPRPAFSLPPGSVKAAPAQARPPSPGNIRPGKREAKGEPEKKDPEKDPQTTGRAPLVKVAEVAAQEVTPVEPEAPAPAPAPAPAPAPTSPPAPASVPATPSAVPATAAPKVSAGTTDPEEATRLLAEKRRLAREQREKEERERREKEELERVAEERARWEEEARRLEAEQARREQQLRLERERAETERAQKQVRCARAGRTISKEEEARVREETERVRQERERHFQREEQERLERKKRLEEIMKRTRRTEAADKKTLDQRNGDIAKGALAGGTGISNENFEESITLPIGSKPSRLDVINRENPEIPLNPILAFEEEETLGPLPQVDGVQTQQTAEVI
Length661
PositionTail
OrganismCavia porcellus (Guinea pig)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Caviidae> Cavia.
Aromaticity0.03
Grand average of hydropathy-1.133
Instability index77.02
Isoelectric point10.05
Molecular weight74786.21
Publications
PubMed=21993624

Function

Annotated function 
GO - Cellular Component
cytosol	GO:0005829	IEA:Ensembl
microtubule cytoskeleton	GO:0015630	IEA:Ensembl

GO - Biological Function
GO - Biological Process
microtubule cytoskeleton organization	GO:0000226	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28768
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     189.93|      26|      26|     393|     418|       1
---------------------------------------------------------------------------
  299-  324 (41.55/16.85)	PANPKA.RSPASSRLW.....LPSK.SLPHLPG
  325-  350 (31.37/10.58)	T......PRPAFSLPPgsvkaAPAQ.ARPPSPG
  354-  380 (32.99/11.57)	PGKREA.KGEPEKKDP.....EKDPqTTGRAPL
  393-  418 (51.06/22.70)	PVEPEA.PAPAPAPAP.....APAP.TSPPAPA
  421-  445 (32.96/11.55)	PATPSAvPATA.AP.K.....VSAG.TTDPEEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     138.13|      27|      27|     458|     484|       2
---------------------------------------------------------------------------
   80-  109 (29.57/ 7.09)	EERK.KRLE.EQRLKEERRRAAvEEkrRQRL..E
  110-  136 (28.98/ 6.82)	EDKE.RLEAvVRRTMERSQKPR.QK..YNRW...
  458-  484 (50.00/16.27)	EQRE.KEER.ERREKEELERVA.EE..RARW..E
  522-  551 (29.59/ 7.10)	AGRTiSKEE.EARVREETERVR.QE..RERHfqR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.97|      17|      52|     498|     518|       3
---------------------------------------------------------------------------
  498-  516 (21.28/18.53)	EQQLrLERERaETERAQKQ
  563-  579 (24.69/ 6.40)	LEEI.MKRTR.RTEAADKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     104.24|      27|      32|     148|     175|       4
---------------------------------------------------------------------------
  148-  171 (38.42/21.44)	..........IHSSDPDRRSVSTMNLSKHVDPVI
  173-  202 (32.57/18.54)	KRLssssatlLNSPDRARR....LQLSPWESNVV
  203-  228 (33.24/14.45)	NRL....ltpTHSFLA..RSKSTAALSG..DAVI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28768 with Med29 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DSCKVQDKKTASNRPSTTISGQNSSHSGNKPDPPPVLRVDDRQRLARERREE
2) NPVDRPKFFVTPPEGSARRRTVHGTTGHKRDRENVPFHLTSGIRRTLSPANPKARSPASSRLWLPSKSLPHLPGTPRPAFSLPPGSVKAAPAQARPPSPGNIRPGKREAKGEPEKKDPEKDPQTTGRAPLVKVAEVAAQEVTPVEPEAPAPAPAPAPAPAPTSPPAPASVPATPSAVPATAAPKVSAGTTDPEEATRLLAEKRRLAREQREKEERERREKEELERVAEERARWEEEARRLEAEQARREQQLRLERERAETERAQKQVRCARAGRTISKEEEARVREETERVRQERERHFQREEQERLERKKRLEEIMKRTRRTEAADKKTLDQRNGDIAKGALAGGTGISNENFEESITLPIGSKPSRLDVINRENPEIPLNPILAFEEEETLGPLPQVDGVQTQQTAEVI
3) PRQKYNRWSWGGPLHGSPRIHSSDPDRRSVSTMNLSKHVDPVI
4) YEKHLEERKKRLEEQRLKEERRRAAVEEKRRQRLEEDKERLEAVVRRTMERS
1
251
129
75
52
661
171
126










Molecular Recognition Features






MoRF SequenceStartStop




1) AEVAAQEVTPVE
2) EATRLL
3) IIMPYKA
4) KYNRWSWGGP
384
444
240
132
395
449
246
141