<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28767

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVVSAASRGAGMFMDTPEDEKTKLISCLSAFKQFWSGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKAILEKILTIPNTVSSAVVQQLLTAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWILGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTSCLASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNESDIITHFSIQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERYLRNRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKNVMNPREDNPWVPDDSYYCKLIGRLSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSSSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLHYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQAMSSGSPVPQSNPVPAPLPGAQ
Length1359
PositionTail
OrganismCavia porcellus (Guinea pig)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Caviidae> Cavia.
Aromaticity0.10
Grand average of hydropathy-0.014
Instability index45.20
Isoelectric point7.58
Molecular weight155244.67
Publications
PubMed=21993624

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28767
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      31|     337|     346|       1
---------------------------------------------------------------------------
  337-  346 (18.69/11.16)	IFFVLFQFAS
  370-  379 (19.45/11.94)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     429.35|     132|     612|     392|     533|       2
---------------------------------------------------------------------------
  392-  533 (212.91/172.23)	PVMKLFDLLYPEKEYIPVPDINKPQSTHA............FAMTCIWIHLNRKAQNDNsklqiP.IP...HSLKLHHEFLQQSLRNKSLQMNDYKIAllcNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTSCLASGSITPLpMNLLdSLTVHA
  999- 1146 (216.44/146.68)	PVTYLYNTLHYYERYLRNRDHLKRKLVHAiigslkdnrpqgWCLSDTYLKNVMNPREDN.....PwVPddsYYCKLIGRLSPGPFPNCDWRFNEFPNP...AAHALHVTCVELMALAVSGKDVGNALLNVVLKSQPLVPRENITAW.MNAI.GLIITA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.39|      25|     666|      27|      53|       3
---------------------------------------------------------------------------
   27-   53 (39.81/38.79)	TPEDEKTKLISC....LSA.FKQfwSGLSQES
  721-  750 (39.58/28.36)	TPHNWASHTLSCfpgpLQAfFKQ..NNVPQES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     220.81|      68|     711|     186|     258|       6
---------------------------------------------------------------------------
  186-  258 (111.82/68.20)	RKLYPEgKLPHWILGNLVSDFVDTFRPTARI..NSICGRcsLLPVVNNsgAICNSWKLDP.....ATLRFPLKGLLPY.DK
  923-  998 (108.99/53.29)	HKKYPE.KLYFEGLAEQVDPPVQIQSPYLPIyfGNVCLR..FLPVFDI..VIHRFLELLPvskslETLLDHLGGLYKFhDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.83|      23|     711|      61|      87|       7
---------------------------------------------------------------------------
   61-   87 (38.25/33.70)	IVKFIHGQHSPKrisfLYDCL..AMAVET
  774-  798 (38.58/23.33)	IITHFSIQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.11|      15|     677|     648|     662|      11
---------------------------------------------------------------------------
  648-  662 (26.26/19.12)	LRLITALGSSE...VQPQ
 1320- 1337 (23.84/16.57)	LRFITHISKMEpaaVPPQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28767 with Med23 domain of Kingdom Metazoa
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