<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28757
Description |
Mediator of RNA polymerase II transcription subunit 6 (Fragment) |
Sequence | MSNPNDPSLDEIQWRSPQIVAQMGGLHSNTILFYFAESPFFERTSNNAVIMAQAMNNMAMYHYIQTREAFETRLKTMSGLEFIVGEEPAETGPGMGTGVWVIRKQTRRKRYQDDDEITVHASFFVVGENIYMAPTLADILASRIMTISSAIAKALPAAEAARKWRPSTGHVYTLPASQPPTTQPKPQEEKPVLDEAGKSASTAAAKHDAPSMDRVAEESLLIHLRYGGEYIDEIPITGKPGEFHLSSTGRKPVLPPQGAAAPTGISAMSGPPMINTKLDDKKDGKADKTPKSATMPKLKRKKSKMSPSVTPAAT |
Length | 314 |
Position | Head |
Organism | Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma atroviride) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Hypocreaceae> Trichoderma.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.465 |
Instability index | 53.51 |
Isoelectric point | 8.86 |
Molecular weight | 34240.72 |
Publications | PubMed=21501500
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP28757
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 59.18| 18| 18| 277| 294| 1
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277- 294 (29.64/17.72) KLDDKKDGKADKTPKSAT
297- 314 (29.54/17.64) KLKRKKSKMSPSVTPAAT
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 59.33| 17| 18| 141| 157| 2
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141- 157 (27.26/16.25) ASRIMTISSAIAKALPA
160- 176 (32.07/20.29) AARKWRPSTGHVYTLPA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 66.03| 18| 18| 235| 252| 3
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235- 252 (32.86/19.64) PITGKPGEFHLSSTGRKP
255- 272 (33.16/19.88) PPQGAAAPTGISAMSGPP
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|