<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28711
Description |
Uncharacterized protein |
Sequence | MTDRLTQLQICLDQMMEQFCAALNYVDKNHDFEPADETEMKMSDRHATVAPPEEFSNTIDELSTDIILKTRQIIRLIDSLPGVDVSTAEQLHKIDTLQKELVKVEEQKVEAIMRKEKLMKDVSGLIAFFVGGISSSREALAQPTESNEQ |
Length | 149 |
Position | Middle |
Organism | Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Torulaspora.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.387 |
Instability index | 42.21 |
Isoelectric point | 4.62 |
Molecular weight | 16884.04 |
Publications | PubMed=22123960
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | RNA polymerase II repressing transcription factor binding GO:0001103 IEA:EnsemblFungi
transcription coactivator activity GO:0003713 IEA:EnsemblFungi
transcription corepressor activity GO:0003714 IEA:EnsemblFungi
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP28711
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 61.04| 14| 15| 77| 90| 1
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59- 72 (15.40/ 7.82) IDELST.DIilKT.RQ
77- 90 (23.81/15.12) IDSLPGVDV..STAEQ
94- 107 (21.83/13.41) IDTLQKELV..KVEEQ
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 39.91| 11| 15| 27| 37| 2
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27- 37 (20.24/12.25) DKNHDFEPADE
44- 54 (19.67/11.77) DRHATVAPPEE
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|