<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28709

Description Uncharacterized protein
SequenceMAGTQNQSASATPVSPAPVGAHRNRLTECFDDIMKVAAEMMVQQQLKTVQLDSAVVNGFSQAQQRVLSEKIHMFHAILDDLQTTLTKSKSYVGTIHEIALEKQKVKEKERADLRKRQEEEEQRKNKEQEEKARREEMEKKADGQRQQQSRPDTGLGFPLETGGGILPDFSAASRDFGGSPSLPISVNQSAAATTPRPIPDSQPSPQSELQQSRASDLGGMSNMDISMFPGLESSGFDMGNFNNGTNGTSRPVESTETTERNGEPNTNEEPGALSMGDNGEDYLTLNDFNDMNIGWSAGGDSGDLDLNGFNI
Length311
PositionTail
OrganismTorulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Torulaspora.
Aromaticity0.05
Grand average of hydropathy-0.840
Instability index63.60
Isoelectric point4.72
Molecular weight33883.87
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblFungi
cytosol	GO:0005829	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
RNA polymerase II repressing transcription factor binding	GO:0001103	IEA:EnsemblFungi
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly	GO:0051123	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28709
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.36|      17|      18|     104|     121|       1
---------------------------------------------------------------------------
  104-  121 (22.96/18.00)	KVKEKERADlRKRQEEEE
  122-  138 (28.41/17.61)	QRKNKEQEE.KARREEME
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.78|      20|      20|     261|     280|       2
---------------------------------------------------------------------------
  245-  265 (26.27/ 9.70)	TNGTSRPVESTETTErNGEPN
  266-  286 (28.51/11.01)	TNEEPGALSMGDNGEdYLTLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.04|      16|      19|     162|     179|       3
---------------------------------------------------------------------------
  162-  177 (29.98/18.97)	GGGILPDFSAASRDFG
  224-  239 (26.06/ 9.44)	DISMFPGLESSGFDMG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28709 with Med2 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KQKVKEKERADLRKRQEEEEQRKNKEQEEKARREEMEKKADGQRQQQSRPDTGLGFPLETGGGILPDFSAASRDFGGSPSLPISVNQSAAATTPRPIPDSQPSPQSELQQSRASDLGGMSNMDISMFPGLESSGFDMGNFNNGTNGTSRPVESTETTERNGEPNTNEEPGALSMGDNGEDYLTLNDFNDMNIGWSAGGD
102
300










Molecular Recognition Features






MoRF SequenceStartStop




1) EDYLTLNDFNDMNIGW
280
295