<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28703

Description Uncharacterized protein
SequenceMSPSKYILTAPDDLHPYVPVNESHQNPEYPDFEPWKHTKEEDQILLNFVAKGFYTTSKVNFESISARSSLQESLPKLSDQLADQFSRVLRIREEEINRIPATDGRSQPSFNELCGPGFLLPSRVTLTEHRRELWLQELGSSFASLPKLSKHIPHGLKRRQVLEQCCAKQIPLKRAIWLIKCCYSMEWKIKTSKSKDSEDGRTLQPLLTKEWTDNFVYILEKLIFEMVQYDSDPAQLKRWRAEVGYFLKLLGNCYTLELIDKEVFHHWLVEFGAKVKNFEFLPLTLHILMVFWEGICGSGKGEGYNAQPLFLVSKVTEMLLSKYHMVSQNKSMINDEKYIINDIKKNGKIKDSILSTLKMLIRRVFENNSLEAFIFSHSSWDLYKPILYDITSTASNECPELTNETRKKLELISYRNESLRIRKPLVPAENGGEDTEPSGSNILKLRSVDIDLTAKLDDNPVDFDWASYLDRNMLHVTQIRQLFFWAIHPSRTTHYEANQLVAKIILLKINTVEAFQEYAVEDVIWSLVFQLAKLDRSTRSMTVALPSMYRLLNILITYGILKVPAYIRKLISSGILYLPESNDKLVHCDVLINLKISPLMKSQYNMVLRNVMEYDPSYFEKYNFDILLEKAESLKQVISGKENPDMGEYPLNIKIMTAEWYLTRICSGGPTSVDKSTLIKNFQIFCVRLDATHYFYKWIEFIVYHQLLDSIEALEALMDIMLCFGKLFSQFINDHILFTKTFILIYTKDLKNKDPNAYAVTSFMPFWKFFIKNFSSALNIDEDLRTELSAVHEEEKAKVERLGKNKQDALNVYLALNEQALKNVSWNFTEIFQTSLRGFLEGKDIASQRRPRGNLLLLMSTNIKEYNKFMSIFLKRKAFKRENLLNLIASKLLTFEQVQNVLDLATVLNLLPIDSTEHGLYFEYHKEQYILNNFETVLVACQKDFSHYYGTFLDVLLKYGTRSKFASVSNKMIARVLKNNPVTHNQILQDMLLYGVSKEEEDDDSTIDEPKAAALYSMLNFTNLWIFQAYTNYQVELISNSDASSLGTFLFEVLDYSSLNCLCAHIFDEIAKPQVLLAIIQIFEHNFFERCKFDSDSNKTYMNVVIEIITSLSQKLQGDVNISDHSFELLSRAFDQFTLLDEETLTAVELQFEITLKIFTIHQNSIFQRIVSSIENRGHDGAGRLIEGTFKLFDETTSNLRLKLMLYELLSSMKSYCIYASTTTTKFNTPAKLLNLPPFQISSFIRKTGKTDADEKADLGLQTIDPKTEDGSDRWFLFDKKESSYVCKLHCEPYHLINNYQSEGISSFNNSCLNLSLFNACFEKKNPS
Length1328
PositionKinase
OrganismTorulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Torulaspora.
Aromaticity0.11
Grand average of hydropathy-0.222
Instability index43.60
Isoelectric point6.12
Molecular weight153649.83
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28703
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.72|      36|      68|      52|      87|       1
---------------------------------------------------------------------------
   52-   87 (61.70/42.10)	GFYTTSKVNFESISARSSLQE......SLPKLSDQLADQFSR
  117-  158 (59.02/39.94)	GFLLPSRVTLTEHRRELWLQElgssfaSLPKLSKHIPHGLKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.50|      32|      69|    1167|    1208|       2
---------------------------------------------------------------------------
 1167- 1204 (43.68/52.31)	FQrIVSSIENRGH...................DGAGRLiegtFkLFDETTSNLRLKL
 1239- 1289 (49.82/26.91)	FQ.ISSFIRKTGKtdadekadlglqtidpkteDGSDRW....F.LFDKKESSYVCKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.08|      10|     126|     962|     971|       5
---------------------------------------------------------------------------
  962-  971 (18.37/12.26)	RSKFASVSNK
 1090- 1099 (20.71/14.88)	RCKFDSDSNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     193.10|      64|     126|     489|     577|       6
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  500-  572 (90.93/103.55)	LVAKIilLKINTVEAFQeyAVEDVIWSLVFQLAKLDRST..RSMTVALPSMYRLLNILI..TYGilkvpAYIRKLIS
  972- 1039 (102.17/55.82)	MIARV..LKNNPVTHNQ..ILQDMLLYGVSKEEEDDDSTidEPKAAALYSMLNFTNLWIfqAYT.....NYQVELIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.02|      31|      34|     825|     858|      14
---------------------------------------------------------------------------
  825-  858 (46.33/36.24)	SWNFTEiFQTSLRGFLEGKDIasQRRPRGNLL...LL
  860-  893 (46.69/26.45)	STNIKE.YNKFMSIFLKRKAF..KRENLLNLIaskLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28703 with Med12 domain of Kingdom Fungi
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