<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28689

Description Piso0_002784 protein
SequenceMNMQQPNMNTWHAMYSVNDRQKIVQILTGTLSELQGNNFDAQKVANMAQEFEKFTFMKSKSREEYLMLIKQKVTQLRNTIRSHNSGGNNMGSGNQMMGQNMGSSVAQNMMGIGQQMGMGSQNMNYMQQQAPVRQQPSVLMQGQMRQGMPAQQRAPSQGQPMQPQQQPQQPQQGQKPSLPTQQQMQQLNNMIRNVPIPQALLAKIPNLPPNTNTWSQIFDLFQKKVIPSSSMPIIKEIHNTHIQLALRQHQQQKLNQLQSQRLSQQQLHQQSQQSQPSQPQPPSHQQQQAQQNHINMNVSNNPNPSKSATPVLGNASPTFNLNNLTPSQKQQFLQRQMQQRNAMASGNQNPNQSPVLHQQSTMPSSAGQGQIPGQTPQMQMNQMNQSSANKPPNFPVTPQDIMKYSADAMRLLTRLQANGQIQPNLDQAQKENFIHKYINHQKALLWKQKNGQAPNNLNAQMTNHSSNANQAQVQRRLQQDNGIGGISMPNTSQMHNQAQTTMGHPQPMVGNSSLGNRPPHVMDNQTQMNTMTSPLMQQRNLSSGGANMMPQSNDKTAKPDASTVSGLLPPLTEEMKLQLRQLIEEVSKTNVALKDMTMLLSQQEKNSVKESIVRISQQYANIDSVISYFFILTRNIEGTKRLIQMKYMTKNIMQKLQQGVILATPDLVEKLRSQYQKYFEFVKEQFNLRKQHLQQQRSQAAQVHQAPAASYPPQAQSQFINNQLRNGSIPQNVAGMPTIQESKQGAMNFGSANVWPNMMSPNNPQQQQQQQQKPPPQQQQPPQQQISSQQAMRNQRPSFANNAMMNNLSPVIPNQMPSVQGTPAAAGSFMAQKPPSRPAANKKAPAATPSSINGAPNRKRSAGRVGPQDTIPTPANNVITPASLANAIKTPNSMNTPQVPASHSNKNTPTEYSPNAQVKTTPNMGKSAEETVGDLLKDTSIDEVVMKRRSLSNVDPALFFRKALSNLLELDESTANGTASATNPSANGKQGKVKSPLSPENTPGEWTCEIKPSVIMSSFKQVDNIKDLADPDIIKVCAQIEESTAEGSMSNDAKRPLEEDDNDIENLFTEKKIKTDDIFDSVHQPINLEDWKSLMVSAMD
Length1100
PositionTail
OrganismPichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) (Hybrid yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Millerozyma.
Aromaticity0.04
Grand average of hydropathy-0.856
Instability index62.42
Isoelectric point9.79
Molecular weight122396.90
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28689
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     122.38|      28|      28|     115|     142|       1
---------------------------------------------------------------------------
  112-  139 (49.84/15.61)	IGQQMGMGSQNMNYMQQQAPVRQQPSVL
  263-  289 (40.31/10.91)	SQQQLHQQSQQSQPSQPQPPSHQQQQA.
  693-  719 (32.24/ 6.93)	LQQQRSQAAQVHQAPAASYP.PQAQSQF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     104.70|      27|      28|     494|     520|       3
---------------------------------------------------------------------------
  325-  352 (34.85/ 8.70)	TPS.QKQQfLQRQMQQRNAMASGNQNPNQ
  492-  517 (34.80/ 8.67)	S..qMHNQ.AQTTMGHPQPMVGNSSLGNR
  775-  795 (35.06/ 8.80)	PPQ.QQQP.PQQ...QISS..QQA.MRNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     153.31|      28|      28|     867|     894|       4
---------------------------------------------------------------------------
  527-  547 (31.76/10.24)	QM..N....TMTS.............PLMQQR...NLS.SG.G...AN
  736-  757 (29.58/ 8.97)	.M..P....TIQE.............S...KQGAMNFG.SA.NV.WPN
  815-  857 (26.94/ 7.45)	QM..PsvQGT.PAaagsfmaqkppsrPAANKKAPAATP.SS.INgAPN
  867-  892 (39.04/14.44)	....P..QDTIPT.............PANNVITPASLA.NA.IK.TPN
  893-  923 (25.99/ 6.90)	SMntP..Q..VPA.............SHSNKNTPTEYSpNAqVKtTPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     131.50|      26|      28|     170|     197|       5
---------------------------------------------------------------------------
  170-  195 (47.56/13.69)	PQQGQKPSLPTQQQ.MQQLNNMIRNVP
  199-  225 (36.54/10.91)	ALLAKIPNLPPNTNtWSQIFDLFQKKV
  366-  391 (47.40/13.61)	AGQGQIPGQTPQMQ.MNQMNQSSANKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     146.48|      30|      30|     400|     429|       6
---------------------------------------------------------------------------
    3-   37 (40.73/20.18)	MQ.QPNMNTWH.A..MYSVNDRQKivQILTgtlsELQGN
  400-  418 (20.85/ 6.37)	............D..IMKYSADAM..RLLT....RLQAN
  419-  450 (42.61/21.49)	GQIQPNLDQAQkEnfIHKYINHQK..ALLW....K.QKN
  451-  480 (42.28/21.26)	GQAPNNLN.AQmT..NHSSNANQA..QVQR....RLQQD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.28|      29|      50|     579|     608|       7
---------------------------------------------------------------------------
  579-  608 (42.14/30.11)	LRQLIEEvSKTNVALKDMTMLLSQQEKNSV
  632-  660 (47.35/29.56)	LTRNIEG.TKRLIQMKYMTKNIMQKLQQGV
  664-  677 (17.80/ 6.20)	TPDLVE...K..........LRSQYQK...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.27|      12|      69|     969|     984|       9
---------------------------------------------------------------------------
  969-  980 (20.88/ 7.75)	ELDESTANGTAS
 1039- 1050 (20.38/ 7.19)	QIEESTAEGSMS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28689 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HLQQQRSQAAQVHQAPAASYPPQAQSQFINNQLRNGSIPQNVAGMPTIQESKQGAMNFGSANVWPNMMSPNNPQQQQQQQQKPPPQQQQPPQQQISSQQAMRNQRPSFANNAMMNNLSPVIPNQMPSVQGTPAAAGSFMAQKPPSRPAANKKAPAATPSSINGAPNRKRSAGRVGPQDTIPTPANNVITPASLANAIKTPNSMNTPQVPASHSNKNTPTEYSPNAQVKTTPNMGKSAEETVGDLLKDTSIDEVVMKR
2) KYINHQKALLWKQKNGQAPNNLNAQMTNHSSNANQAQVQRRLQQDNGIGGISMPNTSQMHNQAQTTMGHPQPMVGNSSLGNRPPHVMDNQTQMNTMTSPLMQQRNLSSGGANMMPQSNDKTAKPDASTVSGLLPP
3) LDESTANGTASATNPSANGKQGKVKSPLSPENTPGEWTCE
4) LRNTIRSHNSGGNNMGSGNQMMGQNMGSSVAQNMMGIGQQMGMGSQNMNYMQQQAPVRQQPSVLMQGQMRQGMPAQQRAPSQGQPMQPQQQPQQPQQGQKPSLPTQQQMQQLNNMIRNVPIPQALLAKIPNLPP
5) SSSMPIIKEIHNTHIQLALRQHQQQKLNQLQSQRLSQQQLHQQSQQSQPSQPQPPSHQQQQAQQNHINMNVSNNPNPSKSATPVLGNASPTFNLNNLTPSQKQQFLQRQMQQRNAMASGNQNPNQSPVLHQQSTMPSSAGQGQIPGQTPQMQMNQMNQSSANKPPNFPVTPQDIMKYSADAMRLLTRLQANGQIQPNLDQAQKENFI
692
436
970
76
228
948
570
1009
209
434










Molecular Recognition Features






MoRF SequenceStartStop




NANANA