<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28686

Description Piso0_002784 protein
SequenceMNMQQPNMNTWHAMYSVNDRQKIVQILTGTLSELQGNNFDAQKVANMAQEFEKFTFMKSKSREEYLMSIKQKVTQLRNTIRSHNSGGNNMSSGNQMMGQNMGSSMTPNMMGMGQQMGMGSQNMNYMQQQAPVRQQPSVLMQGQMRQGMPAQQRPPSQGQPMQPQQQPQQPQQGQKPPLPTQQQMRQLNNMIRNVPIPQALLAKIPNLPPNTNTWSQIFDLFPKKVIPSSSIPIIKEIHNTHIQLALRQHQQQKLNQLQSQRLSQQQLHQQSQQSQASQPQPPSHQQQQAQQNHINMNVSNNPNPSKSGTPVSGNASPNFNLNNLTPSQKQQFLQRQMQQRNAMASGNQNPNQSPVLHQQSTIPSSVGQGQMPGQTPQQMQMNQMNQSNANKPPNFQVTPQDVMKYSADAMRLLTRLQANGQIQPNLDQAQKENFIHKYINHQKALLWKQKNGQAPNNLNTQMTNPSNTANQAQVQRRLQQDNGIGGISMPNASQIYNQAQATMGHQQPMVGNSSLGNRPPHVMDNQAQMNTMTSPLIQQRNLSTGGANMMPQTNDKAAKPDASTVSGLLPPLTEEMKLQLRQLIEEVSKTNVALKDMTMLLSQQEKNSVKESIVRISQQYANIDSVISYFFILTRNIEGTKRLIQMKYMTTNIMQKLQQGVILATPDLVEKLRSQYQKYFEFVKEQFNLRKQHLQQQRSQAGQVHQPPAASYPPQAQSQFINNQLRNGSIPQNVAGMPTIQESKKGAMNFGSANVWPNMMSPNNPQQQQQQPPQQQMSSQQAMRNQRPSFANNAMMNNLSPVIPNQMPSVQGTPAAAGSFMAQKPPSRPSTNKKAPAATPSSINGAPNKKRSAARVGPQDTIPTPANNVITPASLANAIKTPNSMNTPQVPTSHSNKNTPTEYSPNAQVKTTPNMGKSAEETVGDLLKDTSIDEVVMKRRSLSNVDPALFFRKALSNLLELDESTTNGAASATNPSANGKQGKVKSPLSPENTPGEWTCEIKPSVIMSSFKQIDNIKDLADPDIIKVCASIEENSAEGSMPNDAKRLLEEDDNDIENLFTEKKIKTDDIFDSVHQPINLEDWKSLMVSAMD
Length1091
PositionTail
OrganismPichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) (Hybrid yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Millerozyma.
Aromaticity0.04
Grand average of hydropathy-0.849
Instability index59.51
Isoelectric point9.78
Molecular weight121433.88
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28686
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.67|      26|      28|     497|     524|       1
---------------------------------------------------------------------------
  479-  504 (34.68/ 7.91)	QQDNGIGGISMPN.ASQI.YNQAQ.ATMG
  505-  533 (30.99/12.18)	HQQPMVGNSSLGNrPPHVmDNQAQmNTMT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     275.67|      34|      34|     741|     774|       2
---------------------------------------------------------------------------
  133-  171 (42.77/11.43)	R.QQ.P...SvlmQGQM.....RQGmpAQQRPP.SQGQPMQPQQQPQQPQ
  256-  290 (33.73/ 7.16)	Q.LQ.SqrlS...QQQL.....HQQ..SQQ...sQASQPQPPSHQQQQAQ
  334-  363 (36.18/ 8.31)	QrQM.Q...Q...RNAM.....ASG..NQN..P.N.QSP..VLHQQSTIP
  695-  719 (31.59/ 6.15)	Q.QQ.R...S...QAGQ.....VHQ..P....P.AASYP..PQAQSQ...
  740-  773 (61.53/20.29)	I.QE.S...K...KGAM.....NFG..SANVWP.NMMSPNNPQQQQQQPP
  774-  809 (34.01/ 7.29)	Q.QQmS...S...QQAMrnqrpSFA..N.NAMM.NNLSPVIP...NQMPS
  884-  913 (35.87/ 8.17)	S.MN.T...P...QVPT.....SHS..NKNT.P.TEYSPN...AQVKTTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     444.38|      84|     193|     172|     255|       3
---------------------------------------------------------------------------
    4-   98 (87.71/29.86)	..QQPN.....MNTWHAM..YSVNDRQKIVQILtgtlselqgNNFDAQ.......KVANMAQEFEKF..TFMKSK..SreeyLMSIKQ.K.VTQLRNTIRSHNSggnnmssgnQMMG
  172-  255 (147.61/55.31)	QGQKPP.....LPTQQQM..RQLNNMIRNVPIP.........QALLAKIP.NLPPNTNTWSQIFDLFPKKVIPSS..S....IPIIKEIH.NTHIQLALRQHQQ.........QKLN
  291-  332 (50.33/13.98)	QNH............INM..NVSNN.....PNP.........SKSGTPVSgNASPN.......FNL..NNLTPSQ..................KQQF....................
  368-  426 (80.66/26.87)	QGQ.MP.....GQTPQQM...QMNQMNQS.............NA.......NKPPN.......FQVTPQDVMKYSadA....MRLLTRLQaNGQIQPNL..................
  428-  474 (36.54/ 8.13)	QAQKENfihkyINHQKALlwKQ.....KNGQAP.........NNLNTQMT.N.PSNTANQAQV......................................................
  541-  582 (41.54/10.25)	...........................................NLSTGGA.NMMPQTNDKAAK....PDASTVSG..L....LPPLTE.....EMKLQLRQ................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.06|      17|      88|     842|     858|       4
---------------------------------------------------------------------------
  820-  836 (25.43/11.47)	FMAQKPPSRPSTNKKAP
  842-  858 (26.62/12.39)	SINGAPNKKRSAARVGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28686 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALLWKQKNGQAPNNLNTQMTNPSNTANQAQVQRRLQQDNGIGGISMPNASQIYNQAQATMGHQQPMVGNSSLGNRPPHVMDNQAQMNTMTSPLIQQRNLSTGGANMMPQTNDKAAKPDASTVSGLLP
2) EIHNTHIQLALRQHQQQKLNQLQSQRLSQQQLHQQSQQSQASQPQPPSHQQQQAQQNHINMNVSNNPNPSKSGTPVSGNASPNFNLNNLTPSQKQQFLQRQMQQRNAMASGNQNPNQSPVLHQQSTIPSSVGQGQMPGQTPQQMQMNQMNQSNANKPPNFQVTPQDVMK
3) KQHLQQQRSQAGQVHQPPAASYPPQAQSQFINNQLRNGSIPQNVAGMPTIQESKKGAMNFGSANVWPNMMSPNNPQQQQQQPPQQQMSSQQAMRNQRPSFANNAMMNNLSPVIPNQMPSVQGTPAAAGSFMAQKPPSRPSTNKKAPAATPSSINGAPNKKRSAARVGPQDTIPTPANNVITPASLANAIKTPNSMNTPQVPTSHSNKNTPTEYSPNAQVKTTPNMGKSAEETVGDLLKDTSIDEVVMKR
4) LDESTTNGAASATNPSANGKQGKVKSPLSPENTPGEWTC
5) MSIKQKVTQLRNTIRSHNSGGNNMSSGNQMMGQNMGSSMTPNMMGMGQQMGMGSQNMNYMQQQAPVRQQPSVLMQGQMRQGMPAQQRPPSQGQPMQPQQQPQQPQQGQKPPLPTQQQMRQLNNMIRNVPIPQALLAKIPNLPP
444
236
691
961
67
570
404
939
999
209










Molecular Recognition Features






MoRF SequenceStartStop




NANANA