<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28669
Description |
Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MEESLPTRWEIELEFVQSLANIQYLNYLAQNNYLNDERFLNYLKYLEYWKNPNYAKYLVYPNCLHILTLLQSEDFRKSIINPDFMNTLMNDMVKRWQDPESGTDASPSIKTETKDSSIPDSTSPAQISSSENAVAGDSAVKN |
Length | 142 |
Position | Middle |
Organism | Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) (Hybrid yeast) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Debaryomycetaceae> Millerozyma.
|
Aromaticity | 0.11 |
Grand average of hydropathy | -0.617 |
Instability index | 68.55 |
Isoelectric point | 4.56 |
Molecular weight | 16443.15 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP28669
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 58.02| 15| 18| 19| 33| 1
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19- 33 (27.47/16.16) LANIQYLNYLAQNNY
40- 54 (30.56/18.66) LNYLKYLEYWKNPNY
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 47.06| 14| 14| 94| 107| 2
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94- 107 (27.05/17.07) KRWQDPESGTDA.SP
110- 124 (20.01/11.16) KTETKDSSIPDStSP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 43.56| 13| 18| 56| 70| 3
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56- 70 (19.72/15.77) KYLVYPNCLHilTLL
77- 89 (23.84/12.89) KSIINPDFMN..TLM
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