<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28647

Description Uncharacterized protein
SequenceMPPSKYILTPPEDLHPLAAKSANSQNVYPDFDPWAHNEVEDKILLSFVAKGHYNSAKVNFESISARSSLQESLPKVADMLAEQFSKVVNLREQTINKVSSVPDKSIGGKPRFTDLAGPGFSLPNRVTLTDQRKSQWLQELSSPNVSLFKLCRSIPHGFKRKQILEQCYLRQIPLQRAIWLIKSSYSMEWKSLMSKLKPGQINKTIISQLYNLWTNNMVSIMERLVFEMPKYYNDNAQLKVWKLRVSYYINLLGNCYSMGLMDKAVFNHWLVEFVEKVENFEFLPLTLHLLNVFWCGICPLTNDLDSSNDTFLISKITSVLLQKYHIVSQSKSMINDENYIINDLQRNAKLKENILFRIKSYILDIFHNQSLEAFIMPNQNWDTYKNCLYEIIALEKIVGEQYTVIKRKMELITYRNDSLKFNSFIQCPKGSPLLCDSESSMDYNSKYDLHSLLNVQFLDYEMTAILDNVAPGYDWSLFVQQKFTCIKQVNQMILWACHPSRKARYDGPHLVAKLLLLKANCQENPQEYSNIEDKIWSLVFHFSKLNEADLTNILNLTSLYGLLNIFISYGIIKVPTYIRKLISSGIMYIPDSKDKFFHCELLINLKISPLMKNQYNMVLKNIMEYDPTYFMQFSYEKLQLLLAAVKEEMLQDNFENLSSLPTSVKIWVSEWYLSYVCSSFDGTLKQVDKATVIKNFTIFGIQLNEIFHFYKWVEFIVYHQLLSDMDSLGSLIDILLCYENLFPILINDQILFIKTILHIYSKELRFKDKILYELIELNPFWKFFMKSFPYLVEIDSDLQLQLGEVYESERNRVERLMKSNSDVVTLYCDINDIKGESSSKFGIHNFPSIFQQNLKILLKSVDEDTGDKARKGLLLLMFANIGDYNKFMSIFLKRKDFSTKQLIKLISLKLLTLDLVHKVIGDEFLSDIIIHKEYNYGLWFELHKKTFIKKNFKLVASLYQNSDDIEEHKFFIDLLVEYGTYSKLQEQVTNIICNYLKEHRRDYSLIVELLKYGVPEGLLEPIKCVNPTELYRQLNFTSVWIFQALTKYYTEALLNNDLNDGQTMSNFVFDIIDLTQYDVTCSHVFDMVTQVDVIEKLLQVVEADFFQKCLSDEPDDVQFLAVMIETIMKLSRKVTQGNGGITMTEKSFQLLQRSMVKFRQMDKEALSNAEMKLNIYLKIFTVHQKFIFQKICDTLRNSINSDGSNLVTALRELFENTGFNLKLKLLLYDILSSLKSFVIYESTKKGEYTLDQRKIQVPEELHNLPPFHISSFLDEHPSTTMNDFSLLGLVEHQVQSEGEETSHFFIYNKETKEYECSLYVEPFQLLMNHQNREPSMNGHCFNDTALSLSLFDARFDKKNPT
Length1361
PositionKinase
OrganismEremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582) (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Eremothecium.
Aromaticity0.12
Grand average of hydropathy-0.166
Instability index35.23
Isoelectric point6.13
Molecular weight158867.83
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28647
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.82|      29|      56|     782|     812|       1
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  629-  647 (22.38/ 9.52)	.YFMQ.FSY.....EKLQLLLAAVKE.......
  782-  812 (46.89/34.86)	KFFMKSFPYLveIDSDLQLQLGEVYE..SERNR
  840-  870 (43.55/26.06)	KFGIHNFPSI..FQQNLKILLKSVDEdtGDKAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     298.64|      97|     486|     169|     294|       2
---------------------------------------------------------------------------
  169-  271 (156.66/147.50)	L.RQIPLQRAIWLIKSSYSMewksLMSKLKPGQINKTIISQlYNLWTNNM...VSIMERLVFEMPKYYND...NAQLKVWKLRVSYYiNLLGNC.YSMGLMDKAVFNHWLV
  300-  404 (141.97/80.22)	LtNDLDSSNDTFLISKITSV....LLQKYHIVSQSKSMIND.ENYIINDLqrnAKLKENILFRIKSYILDifhNQSLEAFIMPNQNW.DTYKNClYEIIALEKIVGEQYTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.67|      26|      59|     688|     715|       3
---------------------------------------------------------------------------
  688-  715 (43.00/32.65)	DKATVIKnfTIFGIQLNEI.FH...FYKWVEF
  748-  777 (34.67/19.13)	DQILFIK..TILHIYSKELrFKdkiLYELIEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.30|      23|      55|    1057|    1111|       4
---------------------------------------------------------------------------
 1057- 1080 (34.59/75.00)	DLNDGQTMSNFVFDIIDLTQyDVT
 1113- 1135 (37.71/ 9.71)	EPDDVQFLAVMIETIMKLSR.KVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.76|      26|      59|    1266|    1291|       5
---------------------------------------------------------------------------
 1266- 1291 (47.34/27.08)	PFHI.SSFLDEHPSTT...MNDFSL.LGLVE
 1322- 1352 (34.42/17.79)	PFQLlMNHQNREPSMNghcFNDTALsLSLFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.08|      41|     171|     412|     463|       6
---------------------------------------------------------------------------
  412-  456 (69.28/59.41)	ITYRND.SLkfnsFIQ....CPKGSPLL....CDSESSMDYNSKYDLHSLL....NVQ
  469-  522 (55.80/26.53)	VAPGYDwSL....FVQqkftCIKQVNQMilwaCHPSRKARYDGPHLVAKLLllkaNCQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.25|      23|     485|      32|      59|       8
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   32-   59 (29.36/32.97)	DPWAHNEVEDKIlLSFVAkgHYnsAKVN
  524-  546 (43.89/26.51)	NPQEYSNIEDKI.WSLVF..HF..SKLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.26|      26|      49|     883|     908|       9
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  883-  908 (43.43/25.65)	DYNKFMSIFLKRKDFSTKQLIKLISL
  933-  958 (45.83/27.48)	EYNYGLWFELHKKTFIKKNFKLVASL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28647 with Med12 domain of Kingdom Fungi
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