<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28644

Description Uncharacterized protein
SequenceMDLDWRSTLSNQERSKYITELAQILADISQVNGSNRANFDLEKLKKTAEQFETSLYASSSSKEFYLDAMRKRIAAMDAAKKKTLANQKQKAVHAAAAFNAGLPGNMNPTMNPQVFLNQQAQARQHAARPMRAGGMEGSAASAAAAAAGANQAQMLLLRQQQQPQQQPQQQLQQPQQQGIPSNLAAAAQAKRAQLSIQRQQLINEMKVAEIPRELLQRMPNMPPGVTTWQQVTELAQQKRLTQNDLQIAKQVYQMHQQLLIKSKMQQANVNQMNAQQQQPQPAQVPHHQQQQQQHPSNFQQKAMLAQQTAAAAAAAAQQQQQQQQQRPMASQQPQEVPNVLNKLNQLFSPAEQKALYENGKKLVQDLQLAGKLPASLNQQQQILYIKKYINQMVLKKLQQNMRLTQHMGVAGSNGQQQPLPNQVTGRMTPAMSQLSQFQHQQLPQAQPPPPQQQHQQQQQQQQHQKPPQQQQPLPQAQPQQQQQPQPSQHPQHQQQLLQQPQSHKLQSVQQHQQQQAVNPMAQRQYVNPGLNKPVMGGVVPQQVVHQQQAQQQAQQQAQQHQAQQQAQQQAQQQTQQQTIRQSPPQPQQVPKISLPRPTEQDMMVLKRINTEVAKSPLRLSNITNQLTMEQKQAIKNKLQGNQQLLSNVDNFIPTLYLITRNEENVRQLLQIRMLAKEIMDHASKGVFIVPPDVVDKVIFRYQKYYEFIKEQLLRRHQQMLSSRQQPPQQQQQQTQQPGQVKATPAPVGLQQTPPVATNTDIAMQQQRVQGSFQQMQQQIRQQQVKNQQQAQQQAQQQQAQQQAQQQAQQQAQQQAQQQAQQQQAQQQAQQQQAQQQAQQQAQQQQAQQQAQQQAQQQAQQQAQQQQAQQQAQQQQLHVQQQAQQQAHAQLQQSMQLASAPNRLTPQTAIGAAHIPVSAPVNVPSSKVTNDSMKSVGSATPVPGNLTSSAASPMLGRQSVGPGSVAQSQKPLPLKGTPTNTSPSENPYRQDELRLKDLALKKAEIVSRFKHRQEVFSKSSVDLFLSTLADCIGVKDEAVELVSKISPNMINHINGTGKKKITKAQQRIRDQDAVDCYIKDNKLVMQSKFSQGARLYAIHDKELGYCFKDIYGPTDTVDLILDNTECTEETTNKKRSHDSLEISPAESDSSLLNDSKKIKIDSPDDLFMNSNVTLDNKEVAPIGLGLGVDLNDTGTNIWNWNYWESL
Length1205
PositionTail
OrganismEremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582) (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Eremothecium.
Aromaticity0.03
Grand average of hydropathy-0.950
Instability index65.86
Isoelectric point9.75
Molecular weight135641.85
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28644
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.34|      23|      23|     800|     822|       1
---------------------------------------------------------------------------
  451-  472 (42.62/ 6.68)	QQQHQQQQQQQQHQKPPQQ.QQP
  800-  822 (50.40/ 9.56)	QQQAQQQAQQQAQQQAQQQAQQQ
  825-  844 (44.32/ 7.31)	QQQAQ...QQQAQQQAQQQAQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.18|      29|      29|     847|     875|       2
---------------------------------------------------------------------------
  559-  587 (48.80/ 8.36)	QHQAQQQAQQQAQQQTQQQTIRQSPPQPQ
  847-  875 (59.38/12.32)	QQQAQQQAQQQAQQQAQQQQAQQQAQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     167.89|      38|      39|     264|     301|       3
---------------------------------------------------------------------------
  270-  311 (63.87/12.62)	NQMNAQQQQPQPAQVPHHQQQQQQHPSNFQQK..................aMlaqQTAAA
  475-  517 (57.96/10.57)	QAQPQQQQQPQPSQHPQHQQQLLQQPQSHKLQ..............svqqhQ...QQQAV
  717-  768 (46.07/ 6.44)	QQMLSSRQQP.PQ....QQQQQTQQPGQVKATpapvglqqtppvatntdiaM...QQQRV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.65|      23|      23|     915|     937|       4
---------------------------------------------------------------------------
  898-  911 (18.95/ 8.23)	..SAP.....NRLTPQT.....AIGA
  915-  937 (41.85/28.82)	PVSAPVNVPSSKVTNDSM...KSVGS
  940-  960 (23.85/12.63)	PV..PGNLTSS..AASPMlgrQSVG.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.97|      16|      23|     588|     608|       6
---------------------------------------------------------------------------
  588-  603 (29.74/27.37)	QVPK..ISLPRPTEQDMM
  611-  628 (21.23/ 6.08)	EVAKspLRLSNITNQLTM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.41|      30|      39|     116|     154|       9
---------------------------------------------------------------------------
  116-  146 (46.92/11.13)	LNQQAQARQHAARPMRAGGMEGsAASAAAAA
  157-  186 (56.49/20.59)	LRQQQQPQQQPQQQLQQPQQQG.IPSNLAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     186.08|      48|     314|     319|     396|      11
---------------------------------------------------------------------------
  331-  378 (79.43/31.55)	QQPQEVPNVLNKLNQLFSPAEQ..KALY......ENGKKLVQDLQLAGKL...........PASLNQ
  629-  695 (58.84/ 9.83)	EQKQAIKNKLQGNQQLLSNVDNfiPTLYlitrneENVRQLLQIRMLAKEImdhaskgvfivPPDVVD
  966- 1001 (47.81/ 6.68)	.QSQK.PLPLKGTPTNTSPSEN..P..Y......RQDELRLKDLALKK...................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.61|      17|      35|    1137|    1153|      13
---------------------------------------------------------------------------
 1137- 1153 (28.02/22.02)	DSLEISPAESDSSL.LND
 1174- 1191 (24.60/18.35)	DNKEVAPIGLGLGVdLND
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28644 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAAAAAAAQQQQQQQQQRPMASQQPQEVPNVLNKLN
2) AQMLLLRQQQQPQQQPQQQLQQPQQQGIPSNLAAAAQAK
3) AQQQQLHVQQQAQQQAHAQLQQSMQLASAPNRLTPQTAIGAAHIPVSAPVNVPSSKVTNDSMKSVGSATPVPGNLTSSAASPMLGRQSVGPGSVAQSQKPLPLKGTPTNTSPSENPYRQDEL
4) HQQMLSSRQQPPQQQQQQTQQPGQVKATPAPVGLQQTPPVATNTDIAMQQQR
5) MNPTMNPQVFLNQQAQARQHAARPMRAGGMEGSAASAAA
6) QNMRLTQHMGVAGSNGQQQPLPNQVTGRMTPAMSQLSQFQHQQLPQAQPPPPQQQHQQQQQQQQHQKPPQQQQPLPQAQPQQQQQPQPSQHPQHQQQLLQQPQSHKLQSVQQHQQQQAVNPMAQRQYVNPGLNKPVMGGVVPQQVVHQQQAQQQAQQQAQQHQAQQQAQQQAQQQTQQQTIRQSPPQPQQVPKISLPRPTEQDMMVLKR
7) SKMQQANVNQMNAQQQQPQPAQVPHHQQQQQQHPSNFQQKAMLA
309
152
871
716
106
399
262
344
190
992
767
144
607
305










Molecular Recognition Features






MoRF SequenceStartStop




NANANA