<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28639
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MSNNDNNDISSLYPPPPPYIKFFTDENVEKLEEYQKGRKRDDVDGGTNGELANEDRLETALDFLIPPPIPTSGQYRVFGSTWQVKDKLPDLESMGLTQLYKKSDQDSSADDQPREVDYQYKIQELRKLLKSLLLNYLELVGILSINPDKFEEKVVNIKTILVNIHHLLNAYRPHQSRESLIMLLEAQLEYKKGEIEHIKSVCKQVKDKLEEIKSIKV |
Length | 217 |
Position | Middle |
Organism | Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.682 |
Instability index | 32.51 |
Isoelectric point | 5.26 |
Molecular weight | 25091.24 |
Publications | PubMed=22123960
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP28639
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 65.16| 18| 49| 1| 18| 1
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1- 18 (36.54/17.96) MSNND..NNDISSLYPPPPP
51- 70 (28.61/12.96) LANEDrlETALDFLIPPPIP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 123.08| 42| 53| 120| 162| 2
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120- 162 (62.19/47.21) YKIQELRKLLKSLL...LNYL..ELVGILSINpDKFEEKVVNIKTILV
171- 217 (60.88/40.73) YRPHQSRESLIMLLeaqLEYKkgEIEHIKSVC.KQVKDKLEEIKSIKV
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