<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28637

Description Uncharacterized protein
SequenceMNPAKYVLIPPDELHPLVEDNDGKFKNSYPDFEPWVHTRQDDEIMLHFVAKGYYSSSKVNFESISARSSMQESLPKLADELANQFSDIIKIRELEINKISSEAETYNSDTRFSILSGPGFSLPSRMTLSDQRKDQWLNDLSSPYVSLTQMSKFLPHGLKRRGLLEQCCLRKVPIIKAIWLLKCCYSMEWTQLKLKSKDNKDHKDDKEINSQLLKEWTENFIYILEKMLLDMANYYNDPEKLKNWKSGIQYYLKLLGNCYRLELIDKQIFLYWLVEFVGKVENLEYFPLTFHILTIFWQDITTVAENDALMKPLFLVTKITDILLHKYVTISQSRSMISDEKYIINDIKKNNKIKESFLLMIRNLICDLFQNQLLEIFLFPSAKWEIYKPYLYEITNYLGNSEDIHNEAKKKLELISYRNESLKINSTLRSSNVNADELTSVENKNVDLHHVKLNCIDTVLAQALDDNSIDFDWASYVDREITQLSQVVQLVLWAISPSKRKHYEAHQIVARIILLIINSLANLREYVIEDIIWSVVFQIPKLSDEERTLFISLPDLYRLLNTLVNYGIVKVPTYIRKLISSGILYLTSSDDKFFHCTVLINLKISPLMKNQYNMVLRNVMEYDSHYFEDYNFDTINNQVEILRPELMSGESFDYDTLTYNTKTLLGEKILSSICGEELIMVNKQILLKNFDILCVKLDTFHLFYKWVEYIVYHQLIDNTETLEILCDILLRYSKLFSQYINDHILFTKTLILIYTKIVKVNDNVAYSVSSLMPFWKFFMKSFPYAIKYDENLRNELGAIYEEEKLKADKLCKDRFLLKSINEALHGNIANSTGSTFNFPEVFQTNLRTFLSENIDNATRKNSRYMMMLLMNVNRRDYNKFIAVYLKRKTFKIEDLIYLISYKLLTFEQIQNTLTMDFVLTVLSYNHSESSRYNEHIQFYAISKASYISSNFKSIIHSTMKKIDELYEFFLDILVEFGTYSKHLENTIEAIVQFLKDEKCSHYDLIIDLINYGVENKDKDDTQEIVLNESNNLYEFLDFTNLWIFQGYTKYLLQKYLLESNDFERTREFLFETVLASRYSCLCSRLFWAISDPEIMKAVITIFEERFFKNCLDDSEEYNVMWEVIIEIITSLSQQLKVNNNRTSSQSIGVANTRSPSLNNIDFISKNYNTDSWDLNSEDTAEVSSFSIYIESFDAIISHFAKMDKDKLLGMRCKLDSFLKISILNQISIFNFVTKLIKKNEVKYLNDLLENIFTLFHKISFDLSLELMLYEILSSLKSYCIFFATTENSKNKNQNSQSNTNSGSSNISISKAPDKKNNAFVIPSILMELSPFKVSSFTRKERVDEIDDNISLGINTVDTTRENTNRKKSPNNFFFYDKVQNTYLCKFYDEPYHCINNYQSEATSDSFNNSCLNLSFFDAVYERKNPK
Length1426
PositionKinase
OrganismTetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
Aromaticity0.12
Grand average of hydropathy-0.250
Instability index36.60
Isoelectric point5.61
Molecular weight167476.95
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28637
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.93|      37|      57|     654|     693|       1
---------------------------------------------------------------------------
  654-  693 (58.69/43.50)	YDTLTYNTKTLlgeKILSSIC..GEELI..MVNKQILLKNFDIL
  712-  752 (56.24/33.89)	YHQLIDNTETL...EILCDILlrYSKLFsqYINDHILFTKTLIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     191.35|      50|      53|     835|     884|       2
---------------------------------------------------------------------------
  782-  829 (50.95/28.32)	.FPYAI.KYDENLRNELGaiyeeEKLKADKLCKDRF...LLKSI...NEAL...HGN.IA..
  835-  884 (85.01/52.45)	TFNFPE.VFQTNLRTFLS.....ENIDNATRKNSRYMMMLLMNV...NRRD...YNKFIAVY
  889-  939 (55.39/31.47)	TFKIEDlIYLISYKLLTF.....EQIQNT......LTMDFVLTVlsyNHSEssrYNEHIQFY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     141.42|      39|     788|     526|     626|       4
---------------------------------------------------------------------------
  585-  626 (67.17/105.77)	YLTSSDDKFFHCtvlINLKISPLMKNQYNMVLRNVMEYDSHY
 1382- 1420 (74.26/21.35)	YLCKFYDEPYHC...INNYQSEATSDSFNNSCLNLSFFDAVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.98|      35|     788|     373|     454|       5
---------------------------------------------------------------------------
  336-  370 (58.50/70.77)	MIS..DEKYIINDIKKNNKIKESFLLMIRNLICDLFQ
  414-  450 (50.48/20.54)	LISyrNESLKINSTLRSSNVNADELTSVENKNVDLHH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.11|      17|     788|     526|     547|       6
---------------------------------------------------------------------------
  526-  545 (26.26/25.64)	YvieDIIWSVVFQ.IPKLSDE
 1117- 1134 (25.85/10.19)	Y...NVMWEVIIEiITSLSQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28637 with Med12 domain of Kingdom Fungi
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