<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28633

Description Uncharacterized protein
SequenceMEHTDLEERSKNVADLLGVLMDINEINGGNSDTAEKMKVHAKNFEAALFAKSSSRKEYMDNMREKVTAMRNTLSSKKKSKTTDPKAATGGGAPGTVSGAANGGNMPMNMDPQMFLNQQAQLRQQAAHQLRNQQQQQQQQQQQQQRPQLTAQQQQIINQMKSAPIPRELLSRIPNIPPNVNTWQQITELAQQKRLSQQDMQIAKEIYKIHQQLLYKSKLQQRQQHQQQQTPQQQTQSQQATPVPQNGNQGQGQGQVSAMNTSLAPNKNGEYPNILGQINQIFTLEEQRVLLQEAIEACKNFRKTQYGNAMTDANIQNFIRKYINQKALRKIQNIRMAQQQFQNNNNNTNTNANTNTTNNSNHNINASVAPSNNAAQPKASSNTNNNTNNNNINLNNVSGIPTVNGMDSNSNTPNNNSSTTPGNYNNAQINNRQKNLLQTLAPTAQDIEIVKRISSEAARIPLRLSDLTNTLSPQEKDEIKRKLQLNQQLFAQVSNYAPQVYILTKSENFLKEVLQLRIFVKEILGKCSKGIYVVKLDTVDKLIIKYQKYWESMKIQLLRRQQLIQRQQQMQQQVGAQKSQTHPSQGVNNLSRQQQRVQGSLQQIHEQMQGKMQQGQPQQQQQPPPPQITQAQAQAQAQALAQAQAQAQAHAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQMQAKVQAQQRARAQAQAQAQAKAQVQTKAQLQSQTEASSQNGVISNDQISNYLQMMNNNGNLNAKMLQQQQQKINSIGGTPLSSNAELTAAGDMTKGSPAVASVSPANKEVKRAAARGKVGKKSASTAAAIVPQTMSALPADNKDSAASASTNLSPSPLTSIPINTRRLSYAQLESHISQGENPYLNEEMLLKNMNTKKAEIISRYKHRQNIFKFSKIETFLSTLADTMGIKDEDVETVYKIPQSTVDFVNGTGKKKPTKAQQRIRDQDSVTVRINNNNNVIMSSKAEPMTRSYKISNDAISSIFSDIYPIGKFAQANFFKSMPVDQDIVTNSNNITNIKKRKLDELEVSPANSNSSLMSDSKKLKIDSPEDMFVIKPEEDLKTSSKTQNSTITNAGNVWDWNQWTSI
Length1101
PositionTail
OrganismTetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
Aromaticity0.04
Grand average of hydropathy-0.861
Instability index46.14
Isoelectric point9.82
Molecular weight122294.53
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
RNA polymerase II activating transcription factor binding	GO:0001102	IEA:EnsemblFungi
TFIIE-class transcription factor complex binding	GO:0001095	IEA:EnsemblFungi
TFIIH-class transcription factor complex binding	GO:0001097	IEA:EnsemblFungi
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of invasive growth in response to glucose limitation	GO:2000219	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi
regulation of establishment of protein localization to chromosome	GO:0070202	IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly	GO:0051123	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28633
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     287.24|      34|      37|     666|     699|       2
---------------------------------------------------------------------------
  122-  178 (41.22/ 8.04)	RQQAahqlrnQ.QQQQQQQQQQQQRPQLTAQQQQiinqmksapiprellsriPNIPPN
  221-  245 (45.23/ 9.41)	RQ........QHQQQ...QTPQQ...QTQ.SQQA..................TPVPQN
  560-  592 (48.86/10.65)	QQLI......QRQQQMQQQVGAQ.KSQTHPSQGV..................NNLSRQ
  593-  626 (52.54/11.90)	QQRV......QGSLQQIHEQMQGKMQQGQPQQQQ..................QPPPPQ
  669-  702 (58.90/14.07)	QAQA......QAQAQAQAQAQAQAQAQAQAQMQA..................KVQAQQ
  703-  733 (40.50/ 7.80)	RARA......QAQAQAQAKAQVQTKAQLQSQTEA..................SSQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     146.04|      31|      31|     342|     372|       3
---------------------------------------------------------------------------
  342-  372 (56.46/24.90)	NNNNNTNT...NANTNTTNNSNHNINASVAPSNN
  375-  403 (51.55/22.10)	QPKASSNT...NNNTN.NNNINLN.NVSGIPTVN
  411-  441 (38.03/14.40)	TPNNNSSTtpgNYNNAQINNRQKNLLQTLAP...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.94|      22|      32|     796|     826|       4
---------------------------------------------------------------------------
  796-  826 (21.81/39.15)	SVSPANKevKRAAargkvGkkSASTAAAIVP
  830-  851 (38.13/26.10)	SALPADN..KDSA.....A..SASTNLSPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.11|      17|      20|    1025|    1041|       5
---------------------------------------------------------------------------
 1025- 1041 (28.98/16.03)	NSNN..ITNIKKRKLDELE
 1046- 1064 (25.13/13.01)	NSNSslMSDSKKLKIDSPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.46|      19|      51|     922|     940|       7
---------------------------------------------------------------------------
  922-  940 (32.64/20.83)	MG............IKDEDVETVYKIPQSTV
  944-  973 (20.06/ 9.93)	NGtgkkkptkaqqrIRDQDSVTV.RINNNNN
  976-  994 (29.77/18.34)	MS............SKAEPMTRSYKISNDAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.16|      14|      21|     183|     196|       8
---------------------------------------------------------------------------
  183-  196 (22.69/13.91)	QQITELAQQ....KRLSQ
  203-  220 (18.47/ 9.69)	KEIYKIHQQllykSKLQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.04|      12|      15|     305|     316|      12
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  305-  316 (22.12/15.10)	YGNAMTDANIQN
  321-  332 (20.92/13.78)	YINQKALRKIQN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28633 with Med15 domain of Kingdom Fungi
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