<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28632

Description Uncharacterized protein
SequenceMNVTRNNTLEFFNTVESLENLEDKLVMNNFENKDILMEKISSTQKSILPIRLLFNEFIQTMALLNDGKGHKTENNNEEALAKFYLVRDKLVRLSECLQNLSSDMSNLKPLFDLISEYSLKNNSKQFDPLETLKQIDNDVFNSQAALATNAADSQNNGKTKAKNSTSTAATPNSSVNTPITNLGSQTILSNTNASVPALATTPTTVTKGASVASASSKSVTANLSSVNVPAATTKKPRKPRQTKKSTATSKKLQSNSAASPMNPPTPSNITANKRANKASAQTAQSTGNMLGMNGSQQNVAGNMNNNNNNNMVQRNNSISMNSQDFMAMQYKNGNGNGNAPMNNQMMNNQMINNQMINNQMLNQQQMKMNNMGNMNMGNMGNMGNMNNINNMNGMSNMNNMNGMNNVNNMGNMANMNNMNNMANMNNMNNMNNMNHMGNMNNMKMNMNSITPANILSMNVPQDVNAINTNNKTTANKTNKASKSNKPAKTNQTQGQSQSRNQPQAQQTGSQSIGNLDMNEFDLLDLNNLDFGGNIDFGNSMDFA
Length543
PositionTail
OrganismTetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
Aromaticity0.03
Grand average of hydropathy-0.799
Instability index34.11
Isoelectric point9.56
Molecular weight59354.87
Publications
PubMed=22123960

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP28632
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     302.47|      41|      41|     369|     409|       1
---------------------------------------------------------------------------
  288-  320 (50.14/10.09)	.NMLGM.N.....GSQQNVaGN..MNN....N......NNNNM..V.QRNNSIS..M
  321-  368 (44.39/ 8.04)	NSQDFM.AMqyknGN.GN..GNapMNN.qmMN..NQMIN.NQMinN.QMLNQQQmkM
  369-  409 (87.04/23.25)	NNMGNM.NM....GNMGNM.GN..MNN...INNMNGMSNMNNM..N.GMNNVNN..M
  410-  451 (70.15/17.22)	GNMANMnNM....NNMANM.NN..MNN...MNNMNHMGNMNNM..KmNMNSIT...P
  452-  495 (50.74/10.30)	ANILSM.NV....PQDVNA.IN..TNNkttANKTNKASKSNKP..A.KTNQTQG..Q
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.72|      27|      63|     196|     222|       4
---------------------------------------------------------------------------
  196-  222 (43.56/24.10)	PALAT....TPTTVT..KGASVASASSKSVTAN
  229-  255 (30.42/14.78)	PAATTkkprKPRQTK..K....STATSKKLQSN
  260-  286 (32.74/16.43)	PMNPP....TPSNITanKRANKASAQTAQST..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.94|      25|      44|      10|      36|       5
---------------------------------------------------------------------------
   10-   36 (36.53/24.40)	EFFNTVESLENLEDKLVMNNfeNKDIL
   56-   80 (42.41/22.39)	EFIQTMALLNDGKGHKTENN..NEEAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.34|      10|      18|     513|     522|       6
---------------------------------------------------------------------------
  513-  522 (19.48/11.44)	GNLDM.NEFDL
  532-  542 (15.87/ 7.83)	GNIDFgNSMDF
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28632 with Med3 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ALATNAADSQNNGKTKAKNSTSTAATPNSSVNTPITNLGSQTILSNTNASVPALATTPTTVTKGASVASASSKSVTANLSSVNVPAATTKKPRKPRQTKKSTATSKKLQSNSAASPMNPPTPSNITANKRANKASAQTAQSTGNMLGMNGSQQNVAGNMNNNNNNNMVQRNNSISMNSQDFMAMQYKNGNGNGNAPMNNQMMNNQMINNQMINNQMLNQQQMKMNNMGN
2) GMSNMNNMNGMNNVNNMGNMANMNNMNNMANMNNMNNMNNMNHMGNMNNMKMN
3) ITPANILSMNVPQDVNAINTNNKTTANKTNKASKSNKPAKTNQTQGQSQSRNQPQAQQTGSQSIGNLDMN
145
393
449
373
445
518

Molecular Recognition Features

MoRF SequenceStartStop
1) EFDLLDLNN
2) FMAMQ
519
325
527
329