<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28620
Description |
Uncharacterized protein |
Sequence | MTDRLTQLQICLDQMMEQFCATLNYIDKKHDFETIGEFEHKMTDKHATVASAEEFSNTIDELSTDIILKTRQISKLIDSLPGVDVSEDEQLRKIDILQKQLLKEEDEKVEAVKEKEKLLSNLNEVTSLFVAGISKAGTTVDSKDDPLHNDKDTSQI |
Length | 156 |
Position | Middle |
Organism | Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.550 |
Instability index | 28.62 |
Isoelectric point | 4.62 |
Molecular weight | 17728.78 |
Publications | PubMed=22123960
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | RNA polymerase II repressing transcription factor binding GO:0001103 IEA:EnsemblFungi
transcription coactivator activity GO:0003713 IEA:EnsemblFungi
transcription corepressor activity GO:0003714 IEA:EnsemblFungi
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP28620
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 43.13| 14| 15| 49| 62| 1
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49- 62 (21.77/14.28) VASAEEFSNTIDEL
67- 80 (21.36/13.90) ILKTRQISKLIDSL
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|