Description | Mediator of RNA polymerase II transcription subunit 22 |
Sequence | MSNQVLYERLGQSTELISTKLIELIKYSSVDETLEENEDKFQENSKITSATTSILMVNNQTTQLIKGIQDLLVLSRTIREKWLLNQIPEETTEQEGIDKQELDNLKELLKKTMNEIVGQE |
Length | 120 |
Position | Head |
Organism | Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Tetrapisispora. |
Aromaticity | 0.03 |
Grand average of hydropathy | -0.578 |
Instability index | 37.19 |
Isoelectric point | 4.58 |
Molecular weight | 13843.51 |
Publications | PubMed=22123960 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 PIRNR:PIRNR007936 |
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi |
Binary Interactions |
Repeats | >MDP28617 No repeats found |
MoRF Sequence | Start | Stop |
1) GIDKQELDNLKELLKK 2) ISTKLIELIKYSSVDETLEENEDKFQ 3) LIKGIQDLLVLSRTIREKWLLNQIPEETTE 4) NSKITSATTSILM 5) VLYERL | 96 17 64 44 5 | 111 42 93 56 10 |
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