<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28615
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MNEAIVNVHLEDVPKTSSLISWSKNGLIAYVSPCKQSKHNLLLTYLESVNGHSWRLAPPQPVEVKLENNFVPELSLLCWSTLSTDLAVSDVYGNFYIFLAGVGMVDSKDSLPSYELTSYNHMEMIYRDVINQNIKSPINPGAFIIAFKWLNIEKPQILNKPASLINLQQSYVYTYGVNQYAPHGVSHPIPTKQACLALRRNGTLMLYYQGEHKVEYHRVSTNLHDKPMMISNASIGFTNDKEILITTYDNLSGEISTYLATIDWGFLVESAKRQKTDPHYHTPKENQNLPTISLTKIHEMKPLPEYKEGNIYPLRCIDIVSASAEKESKASILISYGAVKIYRYEVVNTVETISDAFSELGTKMNALVESTHPKTIELKDTISRNGSIQSIIIGPSDLHCMILYESGYIDVLDTKTWEVINTSNRQFPPRTITTAFEVGFAFPEIKHKDQLVLAVSPNMTSVVYTEVYNETDDLTLKPIEKVRNTGFQPRDLFATSVALAYRHAYACYTNTFTDDLIILIQFEVQRLRSLLFRQMPDKNDSIKLMLKKFLESIISEAHKSINFQLDAFSKESVDKLLSNPPLQKLLSLQLILGEAQGNSVMSDIAWIVLNLRSTNFGIMFSLSSIYRQISKKKPSEDTLQDSIARGECIISLIGNIKWLMDLMAYFNQELLQLSYFRNDTENSKLNLSNSVVLPIILSKVPRLFLMYAISSMGKTHEILKKLHKDLAESNKLFTPMKEALNRYFTICSGAPLTLSLFEQYLRECDALIAKELTTRLASKEKGYSLKIEQKLVCQGELADDVKDIARILVDRYAHNITREMKVSELYFYNTEWLNIGFNKPARSIEDSSIIVYPQVSNKKVVPRLKLDRDIDALRKIYIYDGKIRRCTRCRSVSLVSDPLVFESPTAIGLWTMVFQRTCICGNTWVNI |
Length | 927 |
Position | Tail |
Organism | Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.149 |
Instability index | 39.81 |
Isoelectric point | 7.79 |
Molecular weight | 105490.47 |
Publications | PubMed=19465905
PubMed=22192698
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP28615
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 146.52| 47| 55| 559| 607| 1
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559- 607 (69.35/51.24) KSINFQLdAFSKESVDKLLS.NPPLQKLLSLQLILGEAQgNSVMSDIAWI
612- 659 (77.17/47.56) RSTNFGI.MFSLSSIYRQISkKKPSEDTLQDSIARGECI.ISLIGNIKWL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 55.76| 17| 54| 6| 23| 2
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6- 23 (28.09/24.28) VNVHLED..VPKTsSLISWS
62- 80 (27.67/18.20) VEVKLENnfVPEL.SLLCWS
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 135.60| 44| 55| 217| 271| 4
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217- 263 (66.58/64.76) HRVSTNLH.DKPMMISN.ASIGFTNDKEI.LITTYDNlsGEISTyLATID
272- 318 (69.01/38.23) KRQKTDPHyHTPKENQNlPTISLTKIHEMkPLPEYKE..GNIYP.LRCID
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 135.70| 42| 59| 402| 447| 5
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402- 447 (64.50/43.91) ILYESGYIDVLDTKTWEVINTSNRQFPPRTItTAFEVGFAFpeiKH
462- 503 (71.21/37.53) VVYTEVYNETDDLTLKPIEKVRNTGFQPRDL.FATSVALAY...RH
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 66.82| 22| 215| 108| 131| 8
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108- 131 (33.31/31.06) KDSLPSYeLTSYNHMEmIYR.DVIN
326- 348 (33.51/20.68) KESKASI.LISYGAVK.IYRyEVVN
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 167.56| 52| 680| 148| 211| 9
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148- 211 (76.08/84.33) KWLNIEkpqiLNKPASLINlqQSYVYTYgvNQYAPHGVSHPIPTKQACLALRRngtlMLYYQGE
831- 882 (91.48/63.00) EWLNIG....FNKPARSIE..DSSIIVY..PQVSNKKVVPRLKLDRDIDALRK....IYIYDGK
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