<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28610

Description Uncharacterized protein
SequenceMCLHSVACVVQYQTSGDNSCTQFFEWLEVDPRTVSTRSLSHQGLQTTMASKIKSRNKLLSSHKKSSLTKSSVKDELVAMKYVMDRPGLPVYAFEDLSKDDIPPMKQTEEVMAEANELTYPDFIPWKDHTQVRKEEVKSNESDDRTYLSKGYFEAPQVGNEYYSGRNLVSATLFQSNENCLNVVSELSRYLANAYTSRNENINKIRHNAGHFKIPQKVTLTATKRESWLNDLSNPNIPLKKIGEKIPHGIRSKLLIDALCTRATPINRALWFTKCVLFSELLTLRRKHQSKILDSNSPEKFELHWLQEWTQQIVGYMEKMSQDIGHIDGAVAKEYYIKKLGYLREFISSLYAETLLDKQYFLSLILKPLGDGFPIDSDTVSHLLSIRQMEDTEDYDVSIQEDLGFTIDYGQRFAALVWVKTFWNDIIGCDYLAKELSESLLLNYFYTTKLSRYPKWFLPEHLRNNLTRSLHDLVIYLFKRNTNNFVIPGNWVLTGDALVSIVSQEMGNVQSNESKKLADQLELINYRNESLIINSNQVETDMNFSSESQVAGKSINGDAKNFRDDRKYCGQQSSSKSPNILEQLDHLRFNEKLAQKILPQMGNQSNDKWKQNLHTIFFWSVSPWRHSAFQNENLSIVCNFLRKSVFSQAEKSVKMEFENEILECIFASLESDSELVDNRKLYIMINELYQLKLITIGSYLRKLIASGVFYTTTDDSKSQKGPNESTQNHLQCLTNLPVLNNKQCDSILRKWNTEGLDFKGTFEKMKKQLQSEILETLFTNKGIIPSDHFEKQWSSIQIGLKFLLVNWFTDEFKTRLVNSPKLVVFTQDILADLYKFYSISDNLPVFFKIIVPTILRNESRMAILYLDGLYFISKLIMRHFKLLKQFVDTSNKSTIANIFRLIMQNYKDLSQRESVAYNFHQVWSFVDSITEKDGTSSRKRKWGDAVSDPENFGIPTYRKDNLETPMQIQSVDLALDHTPKLTDNYSSDDFKNDLAALRVSNSVLLKSESEVNGLKAIAGNTNIDNHLSYWYSKVDCISESEETAIVRLWRHFAAGIAVDVVEKTISSAVSDVLHSACQTNLKILMIKKLVIYDIISLKGVVSLLTNNGKEQLQSLLLQMLLEPDFPNNMALSAAKYQLYRISVYFFKEKNKKQYTCLILQGLTARNLHSCLLDNKEEVKHFLSHSLVTEGRHILSELLVNTSRDDCFDLLNLCLNKSKEDYVGSLSKFEQSIDEINEFNKPFYQALLSILSFSLNVEDKSSATARWEVFIETYLNRTRSEGSSKNLLFGSLFCWVPWQHKLIILEILENKVFTQPLDDTTTVTLTMNGAAINSIAVGFLDTFLSSTVNAVSSPNPFITKFTEFLSRVNTTINRIIIEERHDSLDTLLSIILKLLIIHMSTLCAFIAKNLGDELAENMVKRLISIVDSKYLERQNSKLRVLFHDLLLVMKTSVNDEITTLAGEMLPISNGLQEQQPSPEEARHKEANVIESIATTSQVQHLFAIPQFDDENPFKNTLDDSLVKCAIMLSSDELAFGGDANYINGSNFKLEVPKTDSLNIPSFMGNILSNEKNNRREGSHSRTCVHPFRIRTYELLEDTSHSLNDGCVNLSLFDGYVARENPP
Length1620
PositionKinase
OrganismCandida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.09
Grand average of hydropathy-0.305
Instability index40.96
Isoelectric point6.13
Molecular weight185442.19
Publications
PubMed=19465905
PubMed=22192698

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28610
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.00|      37|     108|     922|     966|       1
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  119-  155 (68.45/36.97)	YPDFIPWKDHTQVRKEEVKSNESDDRTY....LSKGYFEAP
  924-  964 (60.55/44.57)	FVDSITEKDGTSSRKRKWGDAVSDPENFgiptYRKDNLETP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     248.48|      87|     112|     298|     390|       2
---------------------------------------------------------------------------
  284-  385 (127.60/98.20)	RRKHQskildsnspEKF...........ELHWLQEWTQQIVGYmEKMSQDIGhiDGAVAKEYYIKKLG.....YLREFISSLYAETLLDKQYFLsliLKPLGDGFPIDSD...TVSHLLSI
  386-  500 (120.87/75.82)	RQMEDtedydvsiqEDLgftidygqrfaALVWVKTFWNDIIGC.DYLAKELS..ESLLLNYFYTTKLSrypkwFLPEHLRNNLTRSLHDLVIYL...FKRNTNNFVIPGNwvlTGDALVSI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.47|      23|     111|     645|     671|       3
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  645-  667 (37.79/19.46)	FSQAEKSVKMEFENEILECIFAS
  757-  779 (36.69/18.52)	FKGTFEKMKKQLQSEILETLFTN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.39|      29|     111|    1192|    1250|       4
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 1221- 1250 (45.33/76.67)	VGSLSKFEQS.IDEINEFNkPFYQALLSILS
 1335- 1364 (46.07/15.82)	VGFLDTFLSStVNAVSSPN.PFITKFTEFLS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     195.97|      63|     106|    1376|    1438|       5
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 1376- 1438 (101.93/78.53)	EERHDSLDTLLSIILKLLIIHMSTLCAFIAKN.LGDELAENMVKRLISIV........DSKYLERQNSKLRV
 1478- 1549 (94.04/71.76)	EARHKEANVIESIATTSQVQHLFAIPQFDDENpFKNTLDDSLVKCAIMLSsdelafggDANYINGSNFKLEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.77|      18|     140|      93|     110|       6
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   93-  110 (32.45/17.32)	FEDLSKDDIPPMKQTEEV
  228-  245 (31.31/16.48)	LNDLSNPNIPLKKIGEKI
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.29|      25|     428|     620|     644|       8
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  620-  644 (45.90/34.58)	VSPWRHSAFQNENLSIVCNFLRKSV
 1045- 1066 (29.15/18.84)	VRLWRHFA.AGIAVDVVEKTISS..
 1068- 1089 (36.24/25.50)	VSDVLHSACQT.NLKIL..MIKKLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.42|      14|     428|     729|     742|       9
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  729-  742 (27.17/17.60)	LQCLT..NLP..VLNNKQ
 1158- 1175 (16.25/ 7.24)	LQGLTarNLHscLLDNKE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28610 with Med12 domain of Kingdom Fungi
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