<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28605

Description Nuclear pore protein
SequenceMFANKSSGPTFGGGLNFGQPQQQQPQQQPQQQPQQQQQQQQQQQPQVTIGSTTQSTINPPTSLNTTQIDITASLDNSSSDKILKDLLESASNLPKSHIKYNNLGSIRLTLDELERKSQQLRKEAEADCASGNNNNNAKAHYLLAGAGVVATGDIEDELNKIQFPKSTSFYQPASAETVESHLKRRKEESILNTIEQSFAVASNDFDNYINANISIDWKARREQLRKSMGIKDSAKFKEEAAKLSVVWKSTSAAANIFTPLTTTKTASLKQISREKFENYAQVIYALNESRLVDEPFSLCLNFYELNKLQDDLKSKQVAEAWKILQNLTSEKFAKTSQEKKFANYDEVDLQNEISLKSKQFLEGQFLNYIEHIYVKHEKPQNFLPGTNINKVSFFIHQVILKNEPELVNKTLLVNGTPIWALIYYLMRAGLYADANEIVTKNGELFNKFDRNFPVYMKSFVNDHKLSSNLGERIHSEFSQQFQYILNDIDTSVNFDPYKYSVYKIIGKCDLSNPSLPQAVNLSVEDWLWFHLSIINESESSIFENYSLTNLQSKVLSLGAKYFTSSNNPLYLKTLILTGLYELAIQYCYDFINEADAVHLAIGLAYYGALHVYNSNKNEVISVTNNKYEINFGRIIGSYTTAFKISDPKVACEYLITIALVDAQLSHDALKELLLVTREFGALIGELYPETGFIEPGVLELQRKLIGLEDINAFQHDIVRATAIKCEDEGRVFDALLLYQLARDYEATVLLMNNKLADIIATSELDKSISSGGTIDNNLVLLSEHIWRNLCQTSYISKVSPQAKQTCDLLISIIKIRDLFVKRQWREVIAKINKLDLIPADAQDDLLKVRSYSDLITNNKLDENLVKVLPSLLVLVMTCISNLNYEVLARKFQPLSSEREELSRWKKIARNCVVYAGMVQYKMPREVYSLLISLEASL
Length937
PositionTail
OrganismCandida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.09
Grand average of hydropathy-0.305
Instability index42.33
Isoelectric point5.86
Molecular weight106229.46
Publications
PubMed=19465905
PubMed=22192698

Function

Annotated function 
GO - Cellular Component
membrane	GO:0016020	IEA:UniProtKB-KW
nuclear pore	GO:0005643	IEA:UniProtKB-SubCell

GO - Biological Function
structural constituent of nuclear pore	GO:0017056	IEA:InterPro

GO - Biological Process
mRNA transport	GO:0051028	IEA:UniProtKB-KW
protein transport	GO:0015031	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28605
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     165.91|      44|      48|     631|     678|       1
---------------------------------------------------------------------------
   49-   87 (50.33/29.12)	.....IGS...TTQSTINPPTSL..NTTQIDItASLDNSSSDKILKDLL
  630-  673 (76.26/60.85)	NFGRIIGS.Y.TTAFKISDPKVA..CEYLITI.ALVDAQLSHDALKELL
  678-  716 (39.32/23.28)	EFGALIGElYpETGF..IEPGVLelQRKLIGL.EDINA.FQHD......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     218.18|      41|      41|     301|     341|       2
---------------------------------------------------------------------------
  169-  205 (40.25/22.83)	.FYQpasAETVESH..LKRR..K.EES............................IL.NTIEQSFAVASN..D..F
  207-  276 (31.52/16.19)	NYIN...AN.ISID..WKARreQLRKSmgikdsakfkeeaaklsvvWKstsaaanIFTPLTTTKTASLKQisREKF
  282-  300 (26.05/12.03)	VIYA...LN........ESR..LVDEP...................FS.......LC..................L
  301-  341 (67.50/43.56)	NFYE...LNKLQDD..LKSK..QVAEA...................WK.......ILQNLTSEKFAKTSQ..EKKF
  342-  382 (52.86/32.42)	ANYD...EVDLQNEisLKSK..QFLEG....................Q.......FL.NYIEHIYVKHEK..PQNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.82|      12|      41|     397|     409|       3
---------------------------------------------------------------------------
  397-  409 (16.63/15.36)	QVILKNePELVNK
  436-  447 (21.19/13.85)	EIVTKN.GELFNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.10|      25|      41|     538|     562|       4
---------------------------------------------------------------------------
  538-  562 (41.75/26.19)	ESSIFENYSLTNLQSKV.LSLGAKYF
  581-  606 (39.35/24.27)	ELAIQYCYDFINEADAVhLAIGLAYY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     142.64|      35|      80|     753|     789|       5
---------------------------------------------------------------------------
  753-  789 (53.73/42.14)	NKLADII...ATSELDKSISSGGTIDNNlvLLSEHIWRNL
  796-  826 (43.06/27.19)	SKVSP.Q...AKQTCDLLISII.KIRD...LFVKRQWRE.
  832-  868 (45.86/29.46)	NKL.DLIpadAQDDLLKVRSYSDLITNN..KLDENLVKVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.64|      12|      19|      19|      30|       6
---------------------------------------------------------------------------
   19-   30 (26.90/15.75)	QPQQQQPQQQPQ
   35-   46 (25.74/14.81)	QQQQQQQQQQPQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28605 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MFANKSSGPTFGGGLNFGQPQQQQPQQQPQQQPQQQQQQQQQQQPQVTIGSTTQSTINPPTSLNTTQIDITASLD
1
75










Molecular Recognition Features






MoRF SequenceStartStop




NANANA