<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28601

Description Uncharacterized protein
SequenceMNINNGVPNGNNMAGVPSWHGMYTGEERQRVVQIIMDTLSDLHGTNPNFDFQKLTKMAQDFERIVYEKSPSRDDYLKAIKSKVSQLRLQKQQVNGGQSVSPNNQVNQQQQQISQQMARNASNTNPNMGPANPQNLQFLQQQAQARNQSQAQIQARQQQLRQMVNSQQGQGMQSSRPLGAVQPNPQQQTTQQQSQQQQQQQQQTNFTQRQALNANGPTGADQQVPPQLLQLIRSSPIPPPLLTKIPNLPKGVTTWNQIFDCIKRKVISQDILPLVRDIHSTHMQLVMRQQQQKMNVRNEGNIAGNNTNQINDNELKTNQGNPPIGQVNFNNLTPQQRQQLLQRQRESQQQRQLSSGANQPGPGLNQDFGQQGLPQQQGLSQQGPPRPVPQQPVPAQKAPFQHPQSQQQQQHQQQPQQSFDQRPPQFQVTQQDYAKYSNDALTLLNRLQQQKQIAGQLDSNMKETFIRKYILHQKNQLWKQQIAAQSGSTGLGIQNAQSQAQQPIPQIAPNVPIPMQSNGGNSQGKQVPISQQGSPMIGTSNTPSMKPNMAPSNNLSSPVPNQRGPVMNDSSAPPGRAGPAAANPSLSSLLPPLTDEAKLRLRQLIEEVSRNNVLLRDVTTLLSPKDKGAVRDSMNRIQEEYGNVDSIISYFYLFTKNIEGTKRLIQMKYMTKNILENLKRGVYLAGPDLLDKLRNQYAKYFDYVKEQISQRRQQIVGGRNPGVPPQPHAIQGQQQQPPLPPGQQQQSQPRGPPQPQMQAQGVQPMVQNAQGVIEQMFGNSNVQNSPHLFAPTFNQSPQQLNQGLPPQIPQQQQQQQQQFANQGMPMVGGLGPQPTQQQMQMNQTWGNAGNVQNNMQQQFAPNGQQQGVQQVPLQQRNSVSQTKPKKAPPKKKRNSTAAAAATPNAIASSIKTPHNVATPQIQNSLQSPQIKSTPAPSAPTPKPNAPPSVPATTAPSTGPATVSGTTPNTHTTPEIDIFSMSSDSVKRRELSLTDPQQFFVESLRKLLELDGQSKESRVNSAATLCAISTSFRQVQEIDEVCENVF
Length1044
PositionTail
OrganismCandida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.04
Grand average of hydropathy-0.932
Instability index67.48
Isoelectric point10.07
Molecular weight115768.30
Publications
PubMed=19465905
PubMed=22192698

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28601
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     679.32|      84|      84|      46|     129|       1
---------------------------------------------------------------------------
   46-  129 (143.00/40.50)	NP.NFDFQKLTKMAQDFER..I.V...................YEK.SP.SRD..D...........................YLKAIKSKVSQL..R..LQKQQV...NGGQ..S......VSP.....N......N....QVNQ........QQQQISQ.......Q...MARN......ASN.TN.......................PNMGP
  131-  216 (78.09/17.95)	NPqNLQF..LQQQAQA...........................RNQ.SQ.AQ...................................IQARQQQL..RqmVNSQQG...QGMQ..SsrplgaVQP.....NpqqqttQ....QQSQ........QQQQQQQ.......QtnfTQRQ......A...LN.......................AN.GP
  244-  324 (74.37/16.66)	IP.NLP.KGVTTWNQIFDC..I.....................KRK.VI.SQDilP...........................LVRDIHSTHMQLvmR..QQQQKMnvrNEGN..I......AGN.....N.....tN....QIND........NELKTNQ.........................GN.......................PPIG.
  325-  402 (51.18/ 8.60)	..................Q..V.N...................FNNlTPqQRQ..Q...........................LLQ..RQRESQ.......QQRQL...SSGA..N.......QP.....G......P....GLNQdfgqqglpQQQGLSQ.......Q..gPPRPvpqqpvPAQ.KA.......................PFQHP
  403-  459 (62.28/12.46)	QS.QQQQQHQQQPQQSFDQ..R.P...................PQF.QV.TQQ..D...........................YAKYSNDALTLL.nR..LQ....................................................QQKQIAG.......Q...LDSN........................................
  460-  550 (45.56/ 6.65)	............MKETFIRkyI.L...................HQK..............................................NQL..W....KQQI....AAQ..S......GSTglgiqN......A....Q.SQ........AQQPIPQiapnvpiP...MQSN......GGN.SQgkqvpisqqgspmigtsntpsmkPNMAP
  558-  641 (64.42/13.21)	VP.NQRGPVMNDSSAPPGR..AgP...................AAA.NP.SLS..S...........................LLPPLTDE.AKL..R..L.RQLI......E..E......VSR.....N......NvllrDVTT........LLSPKDK.......G...AVRD......SMNrIQ.......................EEYG.
  650-  751 (78.44/18.08)	......FYLFTKNIEGTKR..L.I...................QMK.YM.TK....nilenlkrgvylagpdlldklrnqyakYFDYVKEQISQ.......RRQQI...VGGRnpG......VPP.....Q......P....HAIQ........GQQQQPP.......L...PPGQ......QQQ.SQ.......................PR.GP
  753-  828 (81.97/19.30)	QP.QMQAQGVQPMVQNAQG..V.IeqmfgnsnvqnsphlfaptFNQ.SP......................................................QQL...NQG..........LPP.................QIPQ........QQQQQQQ.......Q...FANQ......GM...........................PMVGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.81|      12|      15|     931|     942|       2
---------------------------------------------------------------------------
  931-  942 (25.60/15.62)	STPAPSAPTPKP
  947-  958 (21.22/11.29)	SVPATTAPSTGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.03|      18|      67|     773|     790|       3
---------------------------------------------------------------------------
  773-  790 (36.26/18.48)	EQM.....FGNS.NVQNS.PHLFAP
  836-  860 (22.12/ 7.92)	QQMqmnqtWGNAgNVQNNmQQQFAP
  873-  888 (27.64/12.04)	QQ.......RNS.VSQTK.PKKAPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.50|      20|      53|     911|     930|       5
---------------------------------------------------------------------------
  911-  930 (36.87/19.37)	TPHNVATPQIQN.SLQSPQIK
  965-  985 (30.63/14.83)	TPNTHTTPEIDIfSMSSDSVK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28601 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DIHSTHMQLVMRQQQQKMNVRNEGNIAGNNTNQINDNELKTNQGNPPIGQVNFNNLTPQQRQQLLQRQRESQQQRQLSSGANQPGPGLNQDFGQQGLPQQQGLSQQGPPRPVPQQPVPAQKAPFQHPQSQQQQQHQQQPQQSFDQRPPQFQVTQQDYAK
2) LRLQKQQVNGGQSVSPNNQVNQQQQQISQQMARNASNTNPNMGPANPQNLQFLQQQAQARNQSQAQIQARQQQLRQMVNSQQGQGMQSSRPLGAVQPNPQQQTTQQQSQQQQQQQQQTNFTQRQALNANGPTGADQQVPPQLLQLIRSSPIPPPLLTKIPNLP
3) LWKQQIAAQSGSTGLGIQNAQSQAQQPIPQIAPNVPIPMQSNGGNSQGKQVPISQQGSPMIGTSNTPSMKPNMAPSNNLSSPVPNQRGPVMNDSSAPPGRAGPAAANPSLSSL
4) RRQQIVGGRNPGVPPQPHAIQGQQQQPPLPPGQQQQSQPRGPPQPQMQAQGVQPMVQNAQGVIEQMFGNSNVQNSPHLFAPTFNQSPQQLNQGLPPQIPQQQQQQQQQFANQGMPMVGGLGPQPTQQQMQMNQTWGNAGNVQNNMQQQFAPNGQQQGVQQVPLQQRNSVSQTKPKKAPPKKKRNSTAAAAATPNAIASSIKTPHNVATPQIQNSLQSPQIKSTPAPSAPTPKPNAPPSVPATTAPSTGPATVSGTTPNTHTTPEIDIFSMSSDSVKRRELSLTD
276
86
476
710
434
248
588
993










Molecular Recognition Features






MoRF SequenceStartStop




1) KAPPKKKRNSTA
885
896